Community-wide benefits of targeted indoor residual spray for malaria control in the Western Kenya Highland
Abstract Background Interest in indoor residual spray (IRS) has been rekindled in recent years, as it is increasingly considered to be a key component of integrated malaria management. Regular spraying of each human dwelling becomes less and less practical as the control area increases. Where malari...
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ftdoajarticles:oai:doaj.org/article:e6d2477aa6b24890b631692177ac56a4 2023-05-15T15:18:20+02:00 Community-wide benefits of targeted indoor residual spray for malaria control in the Western Kenya Highland Minakawa Noboru Githeko Andrew K Zhou Guofa Yan Guiyun 2010-03-01T00:00:00Z https://doi.org/10.1186/1475-2875-9-67 https://doaj.org/article/e6d2477aa6b24890b631692177ac56a4 EN eng BMC http://www.malariajournal.com/content/9/1/67 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-67 1475-2875 https://doaj.org/article/e6d2477aa6b24890b631692177ac56a4 Malaria Journal, Vol 9, Iss 1, p 67 (2010) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2010 ftdoajarticles https://doi.org/10.1186/1475-2875-9-67 2022-12-31T08:36:49Z Abstract Background Interest in indoor residual spray (IRS) has been rekindled in recent years, as it is increasingly considered to be a key component of integrated malaria management. Regular spraying of each human dwelling becomes less and less practical as the control area increases. Where malaria transmission is concentrated around focal points, however, targeted IRS may pose a feasible alternative to mass spraying. Here, the impact of targeted IRS was assessed in the highlands of western Kenya. Methods Indoor residual spray using lambda-cyhalothrin insecticide was carried out during the last week of April 2005 in 1,100 targeted houses, located in the valley bottom areas of Iguhu village, Kakamega district of western Kenya. Although the uphill areas are more densely populated, valleys are believed to be malaria transmission hotspots. The aim of the study was to measurably reduce the vector density and malaria transmission in uphill areas by focusing control on these hotspots. A cohort of 1,058 children from 1-5 yrs of age was randomly selected from a 4 km by 6 km study area for the baseline malaria prevalence survey after pre-clearing malaria infections during the third week of April 2005, and the prevalence of Plasmodium infections was tested bi-weekly. Seasonal changes in mosquito densities 12 months before the IRS and 12 months after the IRS was monitored quarterly based on 300 randomly selected houses. Monthly parasitological surveys were also carried out in the same area with 129-661 randomly selected school children of age 6-13 yrs. Results The result of monthly parasitological surveys indicated that malaria prevalence in school children was reduced by 64.4% in the intervention valley area and by 46.3% in the intervention uphill area after 12 months of follow-ups in contrast to nonintervention areas (valley or uphill). The cohort study showed an average of 4.5% fewer new infections biweekly in the intervention valley compare to nonintervention valley and the relative reduction in incidence rate by week ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Lambda ENVELOPE(-62.983,-62.983,-64.300,-64.300) Malaria Journal 9 1 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Minakawa Noboru Githeko Andrew K Zhou Guofa Yan Guiyun Community-wide benefits of targeted indoor residual spray for malaria control in the Western Kenya Highland |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Interest in indoor residual spray (IRS) has been rekindled in recent years, as it is increasingly considered to be a key component of integrated malaria management. Regular spraying of each human dwelling becomes less and less practical as the control area increases. Where malaria transmission is concentrated around focal points, however, targeted IRS may pose a feasible alternative to mass spraying. Here, the impact of targeted IRS was assessed in the highlands of western Kenya. Methods Indoor residual spray using lambda-cyhalothrin insecticide was carried out during the last week of April 2005 in 1,100 targeted houses, located in the valley bottom areas of Iguhu village, Kakamega district of western Kenya. Although the uphill areas are more densely populated, valleys are believed to be malaria transmission hotspots. The aim of the study was to measurably reduce the vector density and malaria transmission in uphill areas by focusing control on these hotspots. A cohort of 1,058 children from 1-5 yrs of age was randomly selected from a 4 km by 6 km study area for the baseline malaria prevalence survey after pre-clearing malaria infections during the third week of April 2005, and the prevalence of Plasmodium infections was tested bi-weekly. Seasonal changes in mosquito densities 12 months before the IRS and 12 months after the IRS was monitored quarterly based on 300 randomly selected houses. Monthly parasitological surveys were also carried out in the same area with 129-661 randomly selected school children of age 6-13 yrs. Results The result of monthly parasitological surveys indicated that malaria prevalence in school children was reduced by 64.4% in the intervention valley area and by 46.3% in the intervention uphill area after 12 months of follow-ups in contrast to nonintervention areas (valley or uphill). The cohort study showed an average of 4.5% fewer new infections biweekly in the intervention valley compare to nonintervention valley and the relative reduction in incidence rate by week ... |
format |
Article in Journal/Newspaper |
author |
Minakawa Noboru Githeko Andrew K Zhou Guofa Yan Guiyun |
author_facet |
Minakawa Noboru Githeko Andrew K Zhou Guofa Yan Guiyun |
author_sort |
Minakawa Noboru |
title |
Community-wide benefits of targeted indoor residual spray for malaria control in the Western Kenya Highland |
title_short |
Community-wide benefits of targeted indoor residual spray for malaria control in the Western Kenya Highland |
title_full |
Community-wide benefits of targeted indoor residual spray for malaria control in the Western Kenya Highland |
title_fullStr |
Community-wide benefits of targeted indoor residual spray for malaria control in the Western Kenya Highland |
title_full_unstemmed |
Community-wide benefits of targeted indoor residual spray for malaria control in the Western Kenya Highland |
title_sort |
community-wide benefits of targeted indoor residual spray for malaria control in the western kenya highland |
publisher |
BMC |
publishDate |
2010 |
url |
https://doi.org/10.1186/1475-2875-9-67 https://doaj.org/article/e6d2477aa6b24890b631692177ac56a4 |
long_lat |
ENVELOPE(-62.983,-62.983,-64.300,-64.300) |
geographic |
Arctic Lambda |
geographic_facet |
Arctic Lambda |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 9, Iss 1, p 67 (2010) |
op_relation |
http://www.malariajournal.com/content/9/1/67 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-67 1475-2875 https://doaj.org/article/e6d2477aa6b24890b631692177ac56a4 |
op_doi |
https://doi.org/10.1186/1475-2875-9-67 |
container_title |
Malaria Journal |
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9 |
container_issue |
1 |
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1766348529766236160 |