Antimicrobial activity of crude extracts prepared from fungal mycelia
Objective: To evaluate the in vitro antimicrobial property of three different partitioned extracts (petroleum ether, ethanol and water) prepared from some fungal mycelia. Methods: Seven fungal mycelia were prepared, initially extracted with acidified ethanol (0.2 mol/L HCl in 80% ethanol), yielding...
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Wolters Kluwer Medknow Publications
2017
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ftdoajarticles:oai:doaj.org/article:e6ab63eb26734a52b1d850651e1312b3 2023-05-15T15:06:34+02:00 Antimicrobial activity of crude extracts prepared from fungal mycelia Andriy Synytsya Jutamart Monkai Roman Bleha Anna Macurkova Tomas Ruml Juhee Ahn Ekachai Chukeatirote 2017-03-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2016.12.011 https://doaj.org/article/e6ab63eb26734a52b1d850651e1312b3 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169116311406 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.12.011 https://doaj.org/article/e6ab63eb26734a52b1d850651e1312b3 Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 3, Pp 257-261 (2017) Antimicrobial activity Disc diffusion Fungal mycelia Partitioned extracts Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2016.12.011 2022-12-30T23:36:18Z Objective: To evaluate the in vitro antimicrobial property of three different partitioned extracts (petroleum ether, ethanol and water) prepared from some fungal mycelia. Methods: Seven fungal mycelia were prepared, initially extracted with acidified ethanol (0.2 mol/L HCl in 80% ethanol), yielding the raw crude extracts. The obtained extracts were then further partitioned with petroleum ether (F1), ethanol (F2) and water (F3). All the fractions were tested for antimicrobial activity using the disc diffusion assay. Results: Our data showed that all the fractions could inhibit the testing bacteria. However, the inhibitory activity was found to be dependent on (i) the fungal strains used; (ii) the solvent extracted; and (iii) the testing bacteria assayed. In general, the ethanolic extracts (F2) derived from all fungi displayed highest inhibitory activity against the testing bacteria except for Chaetomium sp. Conclusions: The findings of the present study concluded that the extracts prepared from the fungal mycelia had the bioactive compounds with antibacterial property. This study is a pioneering work and further study should be carried out for development of the new drug leads. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 3 257 261 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Antimicrobial activity Disc diffusion Fungal mycelia Partitioned extracts Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Antimicrobial activity Disc diffusion Fungal mycelia Partitioned extracts Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Andriy Synytsya Jutamart Monkai Roman Bleha Anna Macurkova Tomas Ruml Juhee Ahn Ekachai Chukeatirote Antimicrobial activity of crude extracts prepared from fungal mycelia |
topic_facet |
Antimicrobial activity Disc diffusion Fungal mycelia Partitioned extracts Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To evaluate the in vitro antimicrobial property of three different partitioned extracts (petroleum ether, ethanol and water) prepared from some fungal mycelia. Methods: Seven fungal mycelia were prepared, initially extracted with acidified ethanol (0.2 mol/L HCl in 80% ethanol), yielding the raw crude extracts. The obtained extracts were then further partitioned with petroleum ether (F1), ethanol (F2) and water (F3). All the fractions were tested for antimicrobial activity using the disc diffusion assay. Results: Our data showed that all the fractions could inhibit the testing bacteria. However, the inhibitory activity was found to be dependent on (i) the fungal strains used; (ii) the solvent extracted; and (iii) the testing bacteria assayed. In general, the ethanolic extracts (F2) derived from all fungi displayed highest inhibitory activity against the testing bacteria except for Chaetomium sp. Conclusions: The findings of the present study concluded that the extracts prepared from the fungal mycelia had the bioactive compounds with antibacterial property. This study is a pioneering work and further study should be carried out for development of the new drug leads. |
format |
Article in Journal/Newspaper |
author |
Andriy Synytsya Jutamart Monkai Roman Bleha Anna Macurkova Tomas Ruml Juhee Ahn Ekachai Chukeatirote |
author_facet |
Andriy Synytsya Jutamart Monkai Roman Bleha Anna Macurkova Tomas Ruml Juhee Ahn Ekachai Chukeatirote |
author_sort |
Andriy Synytsya |
title |
Antimicrobial activity of crude extracts prepared from fungal mycelia |
title_short |
Antimicrobial activity of crude extracts prepared from fungal mycelia |
title_full |
Antimicrobial activity of crude extracts prepared from fungal mycelia |
title_fullStr |
Antimicrobial activity of crude extracts prepared from fungal mycelia |
title_full_unstemmed |
Antimicrobial activity of crude extracts prepared from fungal mycelia |
title_sort |
antimicrobial activity of crude extracts prepared from fungal mycelia |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2016.12.011 https://doaj.org/article/e6ab63eb26734a52b1d850651e1312b3 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 3, Pp 257-261 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169116311406 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.12.011 https://doaj.org/article/e6ab63eb26734a52b1d850651e1312b3 |
op_doi |
https://doi.org/10.1016/j.apjtb.2016.12.011 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
3 |
container_start_page |
257 |
op_container_end_page |
261 |
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1766338148636295168 |