Responses of the Macroalga Ulva prolifera Müller to Ocean Acidification Revealed by Complementary NMR- and MS-Based Omics Approaches
Ocean acidification (OA) is a dramatic perturbation of seawater environments due to increasing anthropogenic emissions of CO 2 . Several studies indicated that OA frequently induces marine biota stress and a reduction of biodiversity. Here, we adopted the macroalga Ulva prolifera as a model and appl...
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ftdoajarticles:oai:doaj.org/article:e692d048e40946998a23f560face0656 2023-05-15T17:49:54+02:00 Responses of the Macroalga Ulva prolifera Müller to Ocean Acidification Revealed by Complementary NMR- and MS-Based Omics Approaches Carlos Sanchez-Arcos Debora Paris Valerio Mazzella Mirko Mutalipassi Maria Costantini Maria Cristina Buia Eric von Elert Adele Cutignano Valerio Zupo 2022-11-01T00:00:00Z https://doi.org/10.3390/md20120743 https://doaj.org/article/e692d048e40946998a23f560face0656 EN eng MDPI AG https://www.mdpi.com/1660-3397/20/12/743 https://doaj.org/toc/1660-3397 doi:10.3390/md20120743 1660-3397 https://doaj.org/article/e692d048e40946998a23f560face0656 Marine Drugs, Vol 20, Iss 743, p 743 (2022) ocean acidification (OA) Ulva prolifera metabolomics lipidomics LC-MS NMR Biology (General) QH301-705.5 article 2022 ftdoajarticles https://doi.org/10.3390/md20120743 2022-12-30T19:31:11Z Ocean acidification (OA) is a dramatic perturbation of seawater environments due to increasing anthropogenic emissions of CO 2 . Several studies indicated that OA frequently induces marine biota stress and a reduction of biodiversity. Here, we adopted the macroalga Ulva prolifera as a model and applied a complementary multi-omics approach to investigate the metabolic profiles under normal and acidified conditions. Our results show that U. prolifera grows at higher rates in acidified environments. Consistently, we observed lower sucrose and phosphocreatine concentrations in response to a higher demand of energy for growth and a higher availability of essential amino acids, likely related to increased protein biosynthesis. In addition, pathways leading to signaling and deterrent compounds appeared perturbed. Finally, a remarkable shift was observed here for the first time in the fatty acid composition of triglycerides, with a decrease in the relative abundance of PUFAs towards an appreciable increase of palmitic acid, thus suggesting a remodeling in lipid biosynthesis. Overall, our studies revealed modulation of several biosynthetic pathways under OA conditions in which, besides the possible effects on the marine ecosystem, the metabolic changes of the alga should be taken into account considering its potential nutraceutical applications. Article in Journal/Newspaper Ocean acidification Directory of Open Access Journals: DOAJ Articles Marine Drugs 20 12 743 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
ocean acidification (OA) Ulva prolifera metabolomics lipidomics LC-MS NMR Biology (General) QH301-705.5 |
spellingShingle |
ocean acidification (OA) Ulva prolifera metabolomics lipidomics LC-MS NMR Biology (General) QH301-705.5 Carlos Sanchez-Arcos Debora Paris Valerio Mazzella Mirko Mutalipassi Maria Costantini Maria Cristina Buia Eric von Elert Adele Cutignano Valerio Zupo Responses of the Macroalga Ulva prolifera Müller to Ocean Acidification Revealed by Complementary NMR- and MS-Based Omics Approaches |
topic_facet |
ocean acidification (OA) Ulva prolifera metabolomics lipidomics LC-MS NMR Biology (General) QH301-705.5 |
description |
Ocean acidification (OA) is a dramatic perturbation of seawater environments due to increasing anthropogenic emissions of CO 2 . Several studies indicated that OA frequently induces marine biota stress and a reduction of biodiversity. Here, we adopted the macroalga Ulva prolifera as a model and applied a complementary multi-omics approach to investigate the metabolic profiles under normal and acidified conditions. Our results show that U. prolifera grows at higher rates in acidified environments. Consistently, we observed lower sucrose and phosphocreatine concentrations in response to a higher demand of energy for growth and a higher availability of essential amino acids, likely related to increased protein biosynthesis. In addition, pathways leading to signaling and deterrent compounds appeared perturbed. Finally, a remarkable shift was observed here for the first time in the fatty acid composition of triglycerides, with a decrease in the relative abundance of PUFAs towards an appreciable increase of palmitic acid, thus suggesting a remodeling in lipid biosynthesis. Overall, our studies revealed modulation of several biosynthetic pathways under OA conditions in which, besides the possible effects on the marine ecosystem, the metabolic changes of the alga should be taken into account considering its potential nutraceutical applications. |
format |
Article in Journal/Newspaper |
author |
Carlos Sanchez-Arcos Debora Paris Valerio Mazzella Mirko Mutalipassi Maria Costantini Maria Cristina Buia Eric von Elert Adele Cutignano Valerio Zupo |
author_facet |
Carlos Sanchez-Arcos Debora Paris Valerio Mazzella Mirko Mutalipassi Maria Costantini Maria Cristina Buia Eric von Elert Adele Cutignano Valerio Zupo |
author_sort |
Carlos Sanchez-Arcos |
title |
Responses of the Macroalga Ulva prolifera Müller to Ocean Acidification Revealed by Complementary NMR- and MS-Based Omics Approaches |
title_short |
Responses of the Macroalga Ulva prolifera Müller to Ocean Acidification Revealed by Complementary NMR- and MS-Based Omics Approaches |
title_full |
Responses of the Macroalga Ulva prolifera Müller to Ocean Acidification Revealed by Complementary NMR- and MS-Based Omics Approaches |
title_fullStr |
Responses of the Macroalga Ulva prolifera Müller to Ocean Acidification Revealed by Complementary NMR- and MS-Based Omics Approaches |
title_full_unstemmed |
Responses of the Macroalga Ulva prolifera Müller to Ocean Acidification Revealed by Complementary NMR- and MS-Based Omics Approaches |
title_sort |
responses of the macroalga ulva prolifera müller to ocean acidification revealed by complementary nmr- and ms-based omics approaches |
publisher |
MDPI AG |
publishDate |
2022 |
url |
https://doi.org/10.3390/md20120743 https://doaj.org/article/e692d048e40946998a23f560face0656 |
genre |
Ocean acidification |
genre_facet |
Ocean acidification |
op_source |
Marine Drugs, Vol 20, Iss 743, p 743 (2022) |
op_relation |
https://www.mdpi.com/1660-3397/20/12/743 https://doaj.org/toc/1660-3397 doi:10.3390/md20120743 1660-3397 https://doaj.org/article/e692d048e40946998a23f560face0656 |
op_doi |
https://doi.org/10.3390/md20120743 |
container_title |
Marine Drugs |
container_volume |
20 |
container_issue |
12 |
container_start_page |
743 |
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1766156420836753408 |