Natural antibacterial remedy for respiratory tract infections

• Published in: Asian Pacific Journal of Tropical Biomedicine
• Main Author: Reham F. El-Kased
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wolters Kluwer Medknow Publications 2016
• Subjects: Klebsiella pneumonia; Staphylococcus aureus; Streptococcus pyogenes; Pseudomonas aeruginosa; Streptococcus pneumonia; Honey; MIC; MBC; Antibacterial activity; Arctic medicine. Tropical medicine; RC955-962; Biology (General); QH301-705.5; Arctic
• Online Access: https://doi.org/10.1016/j.apjtb.2015.12.002; https://doaj.org/article/e598d777566743009f8b25c3ecbd2f61

Objective: To evaluate the antibacterial activity of Egyptian honey against bacteria causing respiratory tract infections. Methods: Sputum and throat swab specimens were used, from which five bacterial species were isolated, namely, Klebsiella pneumonia, Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa and Streptococcus pneumonia were isolated, identified and grown on suitable media for further identification or confirmation. Different concentrations (100%, 75% and 25%) of honey and simulated honey solution were used for activity assay and estimation of minimum inhibitory concentration and minimum bactericidal concentration. Results: All the tested bacterial isolates were completely susceptible to the 75% concentrations of honey and to the 100% concentration of the simulated honey solution. This may be due to the high osmotic pressure exerted by the high sugar content in both honey samples. Moderate susceptibility of the isolated bacteria to honey at 100% v/v concentration, and resistance to honey at 25% concentration and the 75% and 25% concentrations of simulated honey solution, indicated the presence of other antimicrobial components responsible for the activity other than the osmotic pressure. Therefore, it was suggested that honey showed distinguished antibacterial activities against the most common bacteria causing respiratory infections with varied sensitivity. Conclusions: Honey, a non-toxic, nutritious, safe for human consumption and cheap natural antibacterial agent, should be globalized.