Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs.
Porcine cysticercosis, an infection caused by Taenia solium metacestodes, is continuously being reported in low-income countries of Latin America, Asia, and sub-Saharan Africa. The disease was declared eradicable by the International Task Force for Diseases Eradication (ITFDE) in 1993, and it is lis...
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ftdoajarticles:oai:doaj.org/article:e4e1c47ef780407595e577daf6dd1a65 2023-05-15T15:06:20+02:00 Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. Ernatus Martin Mkupasi Chummy Sikalizyo Sikasunge Helena Aminiel Ngowi Maria Vang Johansen 2013-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0002200 https://doaj.org/article/e4e1c47ef780407595e577daf6dd1a65 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3723597?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002200 https://doaj.org/article/e4e1c47ef780407595e577daf6dd1a65 PLoS Neglected Tropical Diseases, Vol 7, Iss 7, p e2200 (2013) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2013 ftdoajarticles https://doi.org/10.1371/journal.pntd.0002200 2022-12-31T12:40:38Z Porcine cysticercosis, an infection caused by Taenia solium metacestodes, is continuously being reported in low-income countries of Latin America, Asia, and sub-Saharan Africa. The disease was declared eradicable by the International Task Force for Diseases Eradication (ITFDE) in 1993, and it is listed among the 17 WHO Neglected Tropical Diseases and Neglected Zoonoses that are potentially eradicable. In view of that, WHO has proposed a step-wise approach to its elimination, including chemotherapy of infected pigs. Different drugs have been tested on porcine cysticercosis with varying efficacies. These include flubendazole, fenbendazole, albendazole, albendazole sulphoxide, oxfendazole, praziquantel, and nitazoxanide. This review summarises available information on the efficacies and adverse effects shown by these drugs in pigs. Oxfendazole has shown to be effective for the control of porcine cysticercosis; however, it needs to be integrated with other control approaches. There is a need for standardised guidelines for evaluating the efficacy of anthelmintics against porcine cysticercosis, and more efficacy studies are needed since the conclusions so far are based on a limited number of studies using few infected pigs. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 7 7 e2200 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Ernatus Martin Mkupasi Chummy Sikalizyo Sikasunge Helena Aminiel Ngowi Maria Vang Johansen Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Porcine cysticercosis, an infection caused by Taenia solium metacestodes, is continuously being reported in low-income countries of Latin America, Asia, and sub-Saharan Africa. The disease was declared eradicable by the International Task Force for Diseases Eradication (ITFDE) in 1993, and it is listed among the 17 WHO Neglected Tropical Diseases and Neglected Zoonoses that are potentially eradicable. In view of that, WHO has proposed a step-wise approach to its elimination, including chemotherapy of infected pigs. Different drugs have been tested on porcine cysticercosis with varying efficacies. These include flubendazole, fenbendazole, albendazole, albendazole sulphoxide, oxfendazole, praziquantel, and nitazoxanide. This review summarises available information on the efficacies and adverse effects shown by these drugs in pigs. Oxfendazole has shown to be effective for the control of porcine cysticercosis; however, it needs to be integrated with other control approaches. There is a need for standardised guidelines for evaluating the efficacy of anthelmintics against porcine cysticercosis, and more efficacy studies are needed since the conclusions so far are based on a limited number of studies using few infected pigs. |
format |
Article in Journal/Newspaper |
author |
Ernatus Martin Mkupasi Chummy Sikalizyo Sikasunge Helena Aminiel Ngowi Maria Vang Johansen |
author_facet |
Ernatus Martin Mkupasi Chummy Sikalizyo Sikasunge Helena Aminiel Ngowi Maria Vang Johansen |
author_sort |
Ernatus Martin Mkupasi |
title |
Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. |
title_short |
Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. |
title_full |
Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. |
title_fullStr |
Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. |
title_full_unstemmed |
Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. |
title_sort |
efficacy and safety of anthelmintics tested against taenia solium cysticercosis in pigs. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2013 |
url |
https://doi.org/10.1371/journal.pntd.0002200 https://doaj.org/article/e4e1c47ef780407595e577daf6dd1a65 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 7, Iss 7, p e2200 (2013) |
op_relation |
http://europepmc.org/articles/PMC3723597?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002200 https://doaj.org/article/e4e1c47ef780407595e577daf6dd1a65 |
op_doi |
https://doi.org/10.1371/journal.pntd.0002200 |
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PLoS Neglected Tropical Diseases |
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7 |
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7 |
container_start_page |
e2200 |
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