Cutaneous disseminated sporotrichosis associated with diabetes: A case report and literature review.
Background Cutaneous disseminated sporotrichosis (CDS), also called hematogenous sporotrichosis, is a rare condition that usually affects immunocompromised patients. The current work presents the case of a woman with diabetes mellitus associated with CDS. Case presentation A 59-year-old woman with d...
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ftdoajarticles:oai:doaj.org/article:e4b7b52def1d4f368f2ebf2b1136af5f 2023-11-12T04:13:13+01:00 Cutaneous disseminated sporotrichosis associated with diabetes: A case report and literature review. Xiujiao Xia Huilin Zhi Zehu Liu 2023-09-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0011647 https://doaj.org/article/e4b7b52def1d4f368f2ebf2b1136af5f EN eng Public Library of Science (PLoS) https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011647&type=printable https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0011647 https://doaj.org/article/e4b7b52def1d4f368f2ebf2b1136af5f PLoS Neglected Tropical Diseases, Vol 17, Iss 9, p e0011647 (2023) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2023 ftdoajarticles https://doi.org/10.1371/journal.pntd.0011647 2023-10-22T00:42:50Z Background Cutaneous disseminated sporotrichosis (CDS), also called hematogenous sporotrichosis, is a rare condition that usually affects immunocompromised patients. The current work presents the case of a woman with diabetes mellitus associated with CDS. Case presentation A 59-year-old woman with diabetes mellitus presented with a two-year history of ulcerated rashes on the left ankle and both sides of the jaw. Physical examination revealed three annular areas of erythematous and raised plaque with an ulcer over the left ankle and both sides of the jaw. Based on laboratory findings, elevated blood glucose concentration and decreased white cell count were observed. Sporothrix globosa was identified in the mycological culture of biopsied tissue from the three lesions and this was confirmed by DNA sequencing. The skin lesions healed after two-month itraconazole therapy. Conclusions Diabetes is a risk factor for disseminated sporotrichosis, which may be induced by hematogeneous spread, repeated inoculation, or autoinoculation. This study raises awareness among clinicians, with regard to the notion that people with possibly altered immune function are potentially vulnerable to severe clinical forms of sporotrichosis. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 17 9 e0011647 |
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Directory of Open Access Journals: DOAJ Articles |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Xiujiao Xia Huilin Zhi Zehu Liu Cutaneous disseminated sporotrichosis associated with diabetes: A case report and literature review. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Cutaneous disseminated sporotrichosis (CDS), also called hematogenous sporotrichosis, is a rare condition that usually affects immunocompromised patients. The current work presents the case of a woman with diabetes mellitus associated with CDS. Case presentation A 59-year-old woman with diabetes mellitus presented with a two-year history of ulcerated rashes on the left ankle and both sides of the jaw. Physical examination revealed three annular areas of erythematous and raised plaque with an ulcer over the left ankle and both sides of the jaw. Based on laboratory findings, elevated blood glucose concentration and decreased white cell count were observed. Sporothrix globosa was identified in the mycological culture of biopsied tissue from the three lesions and this was confirmed by DNA sequencing. The skin lesions healed after two-month itraconazole therapy. Conclusions Diabetes is a risk factor for disseminated sporotrichosis, which may be induced by hematogeneous spread, repeated inoculation, or autoinoculation. This study raises awareness among clinicians, with regard to the notion that people with possibly altered immune function are potentially vulnerable to severe clinical forms of sporotrichosis. |
format |
Article in Journal/Newspaper |
author |
Xiujiao Xia Huilin Zhi Zehu Liu |
author_facet |
Xiujiao Xia Huilin Zhi Zehu Liu |
author_sort |
Xiujiao Xia |
title |
Cutaneous disseminated sporotrichosis associated with diabetes: A case report and literature review. |
title_short |
Cutaneous disseminated sporotrichosis associated with diabetes: A case report and literature review. |
title_full |
Cutaneous disseminated sporotrichosis associated with diabetes: A case report and literature review. |
title_fullStr |
Cutaneous disseminated sporotrichosis associated with diabetes: A case report and literature review. |
title_full_unstemmed |
Cutaneous disseminated sporotrichosis associated with diabetes: A case report and literature review. |
title_sort |
cutaneous disseminated sporotrichosis associated with diabetes: a case report and literature review. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2023 |
url |
https://doi.org/10.1371/journal.pntd.0011647 https://doaj.org/article/e4b7b52def1d4f368f2ebf2b1136af5f |
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Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 17, Iss 9, p e0011647 (2023) |
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https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011647&type=printable https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0011647 https://doaj.org/article/e4b7b52def1d4f368f2ebf2b1136af5f |
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https://doi.org/10.1371/journal.pntd.0011647 |
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PLOS Neglected Tropical Diseases |
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