Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review
One of the most widely distributed soft coral species, found especially in shallow waters of the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus Sacrophyton . The total number of species belonging to it was estimated to be 40. Sarcophyton species are considered to be a...
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ftdoajarticles:oai:doaj.org/article:e41f674af14e42aa94c08479224a4ea3 2023-05-15T15:05:41+02:00 Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review Yasmin A. Elkhawas Ahmed M. Elissawy Mohamed S. Elnaggar Nada M. Mostafa Eman Al-Sayed Mokhtar M. Bishr Abdel Nasser B. Singab Osama M. Salama 2020-01-01T00:00:00Z https://doi.org/10.3390/md18010041 https://doaj.org/article/e41f674af14e42aa94c08479224a4ea3 EN eng MDPI AG https://www.mdpi.com/1660-3397/18/1/41 https://doaj.org/toc/1660-3397 1660-3397 doi:10.3390/md18010041 https://doaj.org/article/e41f674af14e42aa94c08479224a4ea3 Marine Drugs, Vol 18, Iss 1, p 41 (2020) sacrphyton soft coral terpenoids antimicrobial antitumor antidiabetic anti-inflammatory Biology (General) QH301-705.5 article 2020 ftdoajarticles https://doi.org/10.3390/md18010041 2022-12-30T20:09:32Z One of the most widely distributed soft coral species, found especially in shallow waters of the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus Sacrophyton . The total number of species belonging to it was estimated to be 40. Sarcophyton species are considered to be a reservoir of bioactive natural metabolites. Secondary metabolites isolated from members belonging to this genus show great chemical diversity. They are rich in terpenoids, in particular, cembranoids diterpenes, tetratepenoids, triterpenoids, and ceramide, in addition to steroids, sesquiterpenes, and fatty acids. They showed a broad range of potent biological activities, such as antitumor, neuroprotective, antimicrobial, antiviral, antidiabetic, antifouling, and anti-inflammatory activity. This review presents all isolated secondary metabolites from species of genera Sacrophyton , as well as their reported biological activities covering a period of about two decades (1998−2019). It deals with 481 metabolites, including 323 diterpenes, 39 biscembranoids, 11 sesquiterpenes, 53 polyoxygenated sterols, and 55 miscellaneous and their pharmacological activities. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Pacific Marine Drugs 18 1 41 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
sacrphyton soft coral terpenoids antimicrobial antitumor antidiabetic anti-inflammatory Biology (General) QH301-705.5 |
spellingShingle |
sacrphyton soft coral terpenoids antimicrobial antitumor antidiabetic anti-inflammatory Biology (General) QH301-705.5 Yasmin A. Elkhawas Ahmed M. Elissawy Mohamed S. Elnaggar Nada M. Mostafa Eman Al-Sayed Mokhtar M. Bishr Abdel Nasser B. Singab Osama M. Salama Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
topic_facet |
sacrphyton soft coral terpenoids antimicrobial antitumor antidiabetic anti-inflammatory Biology (General) QH301-705.5 |
description |
One of the most widely distributed soft coral species, found especially in shallow waters of the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus Sacrophyton . The total number of species belonging to it was estimated to be 40. Sarcophyton species are considered to be a reservoir of bioactive natural metabolites. Secondary metabolites isolated from members belonging to this genus show great chemical diversity. They are rich in terpenoids, in particular, cembranoids diterpenes, tetratepenoids, triterpenoids, and ceramide, in addition to steroids, sesquiterpenes, and fatty acids. They showed a broad range of potent biological activities, such as antitumor, neuroprotective, antimicrobial, antiviral, antidiabetic, antifouling, and anti-inflammatory activity. This review presents all isolated secondary metabolites from species of genera Sacrophyton , as well as their reported biological activities covering a period of about two decades (1998−2019). It deals with 481 metabolites, including 323 diterpenes, 39 biscembranoids, 11 sesquiterpenes, 53 polyoxygenated sterols, and 55 miscellaneous and their pharmacological activities. |
format |
Article in Journal/Newspaper |
author |
Yasmin A. Elkhawas Ahmed M. Elissawy Mohamed S. Elnaggar Nada M. Mostafa Eman Al-Sayed Mokhtar M. Bishr Abdel Nasser B. Singab Osama M. Salama |
author_facet |
Yasmin A. Elkhawas Ahmed M. Elissawy Mohamed S. Elnaggar Nada M. Mostafa Eman Al-Sayed Mokhtar M. Bishr Abdel Nasser B. Singab Osama M. Salama |
author_sort |
Yasmin A. Elkhawas |
title |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_short |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_full |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_fullStr |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_full_unstemmed |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_sort |
chemical diversity in species belonging to soft coral genus sacrophyton and its impact on biological activity: a review |
publisher |
MDPI AG |
publishDate |
2020 |
url |
https://doi.org/10.3390/md18010041 https://doaj.org/article/e41f674af14e42aa94c08479224a4ea3 |
geographic |
Arctic Pacific |
geographic_facet |
Arctic Pacific |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Marine Drugs, Vol 18, Iss 1, p 41 (2020) |
op_relation |
https://www.mdpi.com/1660-3397/18/1/41 https://doaj.org/toc/1660-3397 1660-3397 doi:10.3390/md18010041 https://doaj.org/article/e41f674af14e42aa94c08479224a4ea3 |
op_doi |
https://doi.org/10.3390/md18010041 |
container_title |
Marine Drugs |
container_volume |
18 |
container_issue |
1 |
container_start_page |
41 |
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1766337335535861760 |