Humoral immune response of patients bitten by the snake Bothrops erythromelas Resposta imune humoral em pacientes picados pela serpente Bothrops erythromelas
INTRODUCTION: Snake envenomings are a health problem in rural areas of tropical and subtropical countries, but little is known regarding the immune response presented by bitten individuals. The IgM production of patients bitten by Bothrops erythromelas snake was analyzed to identify the effectivenes...
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2010
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ftdoajarticles:oai:doaj.org/article:e285403e8ff2411499c987ad1ff16c96 2023-05-15T15:08:07+02:00 Humoral immune response of patients bitten by the snake Bothrops erythromelas Resposta imune humoral em pacientes picados pela serpente Bothrops erythromelas Karla Patricia Oliveira Luna Edeneide Maria Xavier Vanessa Peruhype Magalhães Pascoal Olindo Assis Martins-Filho Valéria Rêgo Alves Pereira 2010-12-01T00:00:00Z https://doi.org/10.1590/S0037-86822010000600027 https://doaj.org/article/e285403e8ff2411499c987ad1ff16c96 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822010000600027 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 doi:10.1590/S0037-86822010000600027 0037-8682 1678-9849 https://doaj.org/article/e285403e8ff2411499c987ad1ff16c96 Revista da Sociedade Brasileira de Medicina Tropical, Vol 43, Iss 6, Pp 731-732 (2010) Veneno ofídico Western blotting IgM Bothrops erythromelas Snake venom Arctic medicine. Tropical medicine RC955-962 article 2010 ftdoajarticles https://doi.org/10.1590/S0037-86822010000600027 2022-12-30T21:27:05Z INTRODUCTION: Snake envenomings are a health problem in rural areas of tropical and subtropical countries, but little is known regarding the immune response presented by bitten individuals. The IgM production of patients bitten by Bothrops erythromelas snake was analyzed to identify the effectiveness of treatment in this type of envenomation. METHODS: Bothrops erythromelas venom was submitted to electrophoresis and transferred to a nitrocellulose sheet, following incubation with patients' sera. RESULTS: A 38 KDa protein was detected before and 24 h after therapy. CONCLUSIONS: The result suggests that this protein could be used as a marker for individuals envenomed by Bothrops. erythromelas. INTRODUÇÃO: Envenenamentos ofídicos consistem problema de saúde pública em áreas rurais de países tropicais e subtropicais, mas pouco sabe-se sobre a resposta imune apresentada pelos indivíduos picados, por isso a avaliação da produção de IgM por pacientes picados por Bothrops erythromelas identificando a eficácia do tratamento nesse tipo de envenenamento. MÉTODOS: O veneno de Bothrops erythromelas foi submetido a eletroforese e transferido para nitrocelulose, seguindo incubação com soro de pacientes. RESULTADOS: Foi observada proteína de 38KDa antes e 24 horas após o tratamento. CONCLUSÕES: Os resultados sugerem que essa proteína poderia ser utilizada como marcador para indivíduos envenenados pela serpente Bothrops erythromelas. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 43 6 731 732 |
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Veneno ofídico Western blotting IgM Bothrops erythromelas Snake venom Arctic medicine. Tropical medicine RC955-962 |
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Veneno ofídico Western blotting IgM Bothrops erythromelas Snake venom Arctic medicine. Tropical medicine RC955-962 Karla Patricia Oliveira Luna Edeneide Maria Xavier Vanessa Peruhype Magalhães Pascoal Olindo Assis Martins-Filho Valéria Rêgo Alves Pereira Humoral immune response of patients bitten by the snake Bothrops erythromelas Resposta imune humoral em pacientes picados pela serpente Bothrops erythromelas |
topic_facet |
Veneno ofídico Western blotting IgM Bothrops erythromelas Snake venom Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: Snake envenomings are a health problem in rural areas of tropical and subtropical countries, but little is known regarding the immune response presented by bitten individuals. The IgM production of patients bitten by Bothrops erythromelas snake was analyzed to identify the effectiveness of treatment in this type of envenomation. METHODS: Bothrops erythromelas venom was submitted to electrophoresis and transferred to a nitrocellulose sheet, following incubation with patients' sera. RESULTS: A 38 KDa protein was detected before and 24 h after therapy. CONCLUSIONS: The result suggests that this protein could be used as a marker for individuals envenomed by Bothrops. erythromelas. INTRODUÇÃO: Envenenamentos ofídicos consistem problema de saúde pública em áreas rurais de países tropicais e subtropicais, mas pouco sabe-se sobre a resposta imune apresentada pelos indivíduos picados, por isso a avaliação da produção de IgM por pacientes picados por Bothrops erythromelas identificando a eficácia do tratamento nesse tipo de envenenamento. MÉTODOS: O veneno de Bothrops erythromelas foi submetido a eletroforese e transferido para nitrocelulose, seguindo incubação com soro de pacientes. RESULTADOS: Foi observada proteína de 38KDa antes e 24 horas após o tratamento. CONCLUSÕES: Os resultados sugerem que essa proteína poderia ser utilizada como marcador para indivíduos envenenados pela serpente Bothrops erythromelas. |
format |
Article in Journal/Newspaper |
author |
Karla Patricia Oliveira Luna Edeneide Maria Xavier Vanessa Peruhype Magalhães Pascoal Olindo Assis Martins-Filho Valéria Rêgo Alves Pereira |
author_facet |
Karla Patricia Oliveira Luna Edeneide Maria Xavier Vanessa Peruhype Magalhães Pascoal Olindo Assis Martins-Filho Valéria Rêgo Alves Pereira |
author_sort |
Karla Patricia Oliveira Luna |
title |
Humoral immune response of patients bitten by the snake Bothrops erythromelas Resposta imune humoral em pacientes picados pela serpente Bothrops erythromelas |
title_short |
Humoral immune response of patients bitten by the snake Bothrops erythromelas Resposta imune humoral em pacientes picados pela serpente Bothrops erythromelas |
title_full |
Humoral immune response of patients bitten by the snake Bothrops erythromelas Resposta imune humoral em pacientes picados pela serpente Bothrops erythromelas |
title_fullStr |
Humoral immune response of patients bitten by the snake Bothrops erythromelas Resposta imune humoral em pacientes picados pela serpente Bothrops erythromelas |
title_full_unstemmed |
Humoral immune response of patients bitten by the snake Bothrops erythromelas Resposta imune humoral em pacientes picados pela serpente Bothrops erythromelas |
title_sort |
humoral immune response of patients bitten by the snake bothrops erythromelas resposta imune humoral em pacientes picados pela serpente bothrops erythromelas |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2010 |
url |
https://doi.org/10.1590/S0037-86822010000600027 https://doaj.org/article/e285403e8ff2411499c987ad1ff16c96 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 43, Iss 6, Pp 731-732 (2010) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822010000600027 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 doi:10.1590/S0037-86822010000600027 0037-8682 1678-9849 https://doaj.org/article/e285403e8ff2411499c987ad1ff16c96 |
op_doi |
https://doi.org/10.1590/S0037-86822010000600027 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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43 |
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6 |
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731 |
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732 |
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