Assessing dehydration status in dengue patients using urine colourimetry and mobile phone technology.
Background Dengue is a systemic and dynamic disease with symptoms ranging from undifferentiated fever to dengue shock syndrome. Assessment of patients' severity of dehydration is integral to appropriate care and management. Urine colour has been shown to have a high correlation with overall ass...
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ftdoajarticles:oai:doaj.org/article:e19d653b33304539b66af0bfc5d9a673 2023-05-15T15:15:30+02:00 Assessing dehydration status in dengue patients using urine colourimetry and mobile phone technology. Natalie Chew Abdul Muhaimin Noor Azhar Aida Bustam Mohamad Shafiq Azanan Crystal Wang Lucy C S Lum 2020-09-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0008562 https://doaj.org/article/e19d653b33304539b66af0bfc5d9a673 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0008562 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008562 https://doaj.org/article/e19d653b33304539b66af0bfc5d9a673 PLoS Neglected Tropical Diseases, Vol 14, Iss 9, p e0008562 (2020) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.1371/journal.pntd.0008562 2022-12-31T07:36:44Z Background Dengue is a systemic and dynamic disease with symptoms ranging from undifferentiated fever to dengue shock syndrome. Assessment of patients' severity of dehydration is integral to appropriate care and management. Urine colour has been shown to have a high correlation with overall assessment of hydration status. This study tests the feasibility of measuring dehydration severity in dengue fever patients by comparing urine colour captured by mobile phone cameras to established laboratory parameters. Methodology/principal findings Photos of urine samples were taken in a customized photo booth, then processed using Adobe Photoshop to index urine colour into the red, green, and blue (RGB) colour space and assigned a unique RGB value. The RGB values were then correlated with patients' clinical and laboratory hydration indices using Pearson's correlation and multiple linear regression. There were strong correlations between urine osmolality and the RGB of urine colour, with r = -0.701 (red), r = -0.741 (green), and r = -0.761 (blue) (all p-value <0.05). There were strong correlations between urine specific gravity and the RGB of urine colour, with r = -0.759 (red), r = -0.785 (green), and r = -0.820 (blue) (all p-value <0.05). The blue component had the highest correlations with urine specific gravity and urine osmolality. There were moderate correlations between RGB components and serum urea, at r = -0.338 (red), -0.329 (green), -0.360 (blue). In terms of urine biochemical parameters linked to dehydration, multiple linear regression studies showed that the green colourimetry code was predictive of urine osmolality (β coefficient -0.082, p-value <0.001) while the blue colourimetry code was predictive of urine specific gravity (β coefficient -2,946.255, p-value 0.007). Conclusions/significance Urine colourimetry using mobile phones was highly correlated with the hydration status of dengue patients, making it a potentially useful hydration status tool. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 14 9 e0008562 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Natalie Chew Abdul Muhaimin Noor Azhar Aida Bustam Mohamad Shafiq Azanan Crystal Wang Lucy C S Lum Assessing dehydration status in dengue patients using urine colourimetry and mobile phone technology. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Dengue is a systemic and dynamic disease with symptoms ranging from undifferentiated fever to dengue shock syndrome. Assessment of patients' severity of dehydration is integral to appropriate care and management. Urine colour has been shown to have a high correlation with overall assessment of hydration status. This study tests the feasibility of measuring dehydration severity in dengue fever patients by comparing urine colour captured by mobile phone cameras to established laboratory parameters. Methodology/principal findings Photos of urine samples were taken in a customized photo booth, then processed using Adobe Photoshop to index urine colour into the red, green, and blue (RGB) colour space and assigned a unique RGB value. The RGB values were then correlated with patients' clinical and laboratory hydration indices using Pearson's correlation and multiple linear regression. There were strong correlations between urine osmolality and the RGB of urine colour, with r = -0.701 (red), r = -0.741 (green), and r = -0.761 (blue) (all p-value <0.05). There were strong correlations between urine specific gravity and the RGB of urine colour, with r = -0.759 (red), r = -0.785 (green), and r = -0.820 (blue) (all p-value <0.05). The blue component had the highest correlations with urine specific gravity and urine osmolality. There were moderate correlations between RGB components and serum urea, at r = -0.338 (red), -0.329 (green), -0.360 (blue). In terms of urine biochemical parameters linked to dehydration, multiple linear regression studies showed that the green colourimetry code was predictive of urine osmolality (β coefficient -0.082, p-value <0.001) while the blue colourimetry code was predictive of urine specific gravity (β coefficient -2,946.255, p-value 0.007). Conclusions/significance Urine colourimetry using mobile phones was highly correlated with the hydration status of dengue patients, making it a potentially useful hydration status tool. |
format |
Article in Journal/Newspaper |
author |
Natalie Chew Abdul Muhaimin Noor Azhar Aida Bustam Mohamad Shafiq Azanan Crystal Wang Lucy C S Lum |
author_facet |
Natalie Chew Abdul Muhaimin Noor Azhar Aida Bustam Mohamad Shafiq Azanan Crystal Wang Lucy C S Lum |
author_sort |
Natalie Chew |
title |
Assessing dehydration status in dengue patients using urine colourimetry and mobile phone technology. |
title_short |
Assessing dehydration status in dengue patients using urine colourimetry and mobile phone technology. |
title_full |
Assessing dehydration status in dengue patients using urine colourimetry and mobile phone technology. |
title_fullStr |
Assessing dehydration status in dengue patients using urine colourimetry and mobile phone technology. |
title_full_unstemmed |
Assessing dehydration status in dengue patients using urine colourimetry and mobile phone technology. |
title_sort |
assessing dehydration status in dengue patients using urine colourimetry and mobile phone technology. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2020 |
url |
https://doi.org/10.1371/journal.pntd.0008562 https://doaj.org/article/e19d653b33304539b66af0bfc5d9a673 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 14, Iss 9, p e0008562 (2020) |
op_relation |
https://doi.org/10.1371/journal.pntd.0008562 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008562 https://doaj.org/article/e19d653b33304539b66af0bfc5d9a673 |
op_doi |
https://doi.org/10.1371/journal.pntd.0008562 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
14 |
container_issue |
9 |
container_start_page |
e0008562 |
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