Antihyperglycemic effect of Ocimum plants: A short review

• Published in: Asian Pacific Journal of Tropical Biomedicine
• Main Authors: Raiya Adiba Antora, Rabeta Mohd Salleh
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wolters Kluwer Medknow Publications 2017
• Subjects: Antihyperglycemic effect; Hyperglycemia; Diabetes mellitus; Bioactive compounds; Arctic medicine. Tropical medicine; RC955-962; Biology (General); QH301-705.5; Arctic
• Online Access: https://doi.org/10.1016/j.apjtb.2017.07.010; https://doaj.org/article/e0df54c999a540ea8738e5c98a86100f

This present review provides information on the antihyperglycemic effect of the plants belonging to the genus Ocimum. The species of this genus which mostly show significant antihyperglycemic effects are Ocimum tenuiflorum L., Ocimum basilicum L., Ocimum gratissimum L. and Ocimum canum L. The results were shown in both in vitro and in vivo studies. The anti-hyperglycemic activities of different extracts from all these species are reported here. Aqueous extracts are common to show a satisfactory result for all the species. The results for ethanol, methanol, ethyl-acetate, petroleum ether extracts, chloroform and hexane fraction of ethanol extract are also presented here. Some of the results showed a better effect than the standard medicine. Eugenol is the most important bioactive compound among all the components for reducing blood glucose level. Other components include polyphenols, caffeic acid, p-coumaric acid compound and chichoric acid, which are reportedly found in these species. There are fewer studies performed to identify the phytochemical components which are responsible for these plants blood glucose, serum glucose and plasma glucose lowering effect. This review presents the studies which have been done lately to establish the antihyperglycemic effects of these plants with a view to identify the core components responsible for this activity in near future.