The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya
Abstract Background Health facility stock-outs of artemether-lumefantrine (AL), the common first-line therapy for uncomplicated malaria across Africa, adversely affect effective malaria case-management. They have been previously reported on various scales in time and space, however the magnitude of...
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ftdoajarticles:oai:doaj.org/article:e093f9a27c5b434ea208c8d076c5efd3 2023-05-15T15:17:53+02:00 The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya Sudoi Raymond K Githinji Sophie Nyandigisi Andrew Muturi Alex Snow Robert W Zurovac Dejan 2012-02-01T00:00:00Z https://doi.org/10.1186/1475-2875-11-37 https://doaj.org/article/e093f9a27c5b434ea208c8d076c5efd3 EN eng BMC http://www.malariajournal.com/content/11/1/37 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-37 1475-2875 https://doaj.org/article/e093f9a27c5b434ea208c8d076c5efd3 Malaria Journal, Vol 11, Iss 1, p 37 (2012) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2012 ftdoajarticles https://doi.org/10.1186/1475-2875-11-37 2022-12-31T08:27:31Z Abstract Background Health facility stock-outs of artemether-lumefantrine (AL), the common first-line therapy for uncomplicated malaria across Africa, adversely affect effective malaria case-management. They have been previously reported on various scales in time and space, however the magnitude of the problem and trends over time are less clear. Here, 2010-2011 data are reported from public facilities in Kenya where alarming stock-outs were revealed in 2008. Methods Data were collected between January 2010 and June 2011 as part of 18 monthly cross-sectional surveys undertaken at nationally representative samples of public health facilities. The primary monitoring indicator was total stock-out of all four weight-specific AL packs. The secondary indicators were stock-outs of at least one AL pack and individual stock-outs for each AL pack. Monthly proportions and summary means of the proportions over the monitoring period were measured for each indicator. Stock-out trends were assessed using linear regression. Results The number of surveyed facilities across 18 time points ranged between 162 and 176 facilities. The stock-out means of the proportion of health facilities were 11.6% for total AL stock-out, 40.6% for stock-out of at least one AL pack, and between 20.5% and 27.4% for stock-outs of individual AL packs. Monthly decrease of the total AL stock-out was 0.005% (95% CI: -0.5 to +0.5; p = 0.983). Monthly decrease in the stock-out of at least one AL pack was 0.7% (95% CI: -1.5 to +0.3; p = 0.058) while stock-outs of individual AL packs decreased monthly between 0.2% for AL 24-pack and 0.7% for AL six-pack without statistical significance for any of the weight-specific packs. Conclusions Despite lower levels of AL stock-outs compared to the reports in 2008, the stock-outs at Kenyan facilities during 2010-2011 are still substantial and of particular worry for the most detrimental:- simultaneous absence of any AL pack. Only minor decrease was observed in the stock-outs of individual AL packs. Recently launched ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 11 1 37 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Sudoi Raymond K Githinji Sophie Nyandigisi Andrew Muturi Alex Snow Robert W Zurovac Dejan The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Health facility stock-outs of artemether-lumefantrine (AL), the common first-line therapy for uncomplicated malaria across Africa, adversely affect effective malaria case-management. They have been previously reported on various scales in time and space, however the magnitude of the problem and trends over time are less clear. Here, 2010-2011 data are reported from public facilities in Kenya where alarming stock-outs were revealed in 2008. Methods Data were collected between January 2010 and June 2011 as part of 18 monthly cross-sectional surveys undertaken at nationally representative samples of public health facilities. The primary monitoring indicator was total stock-out of all four weight-specific AL packs. The secondary indicators were stock-outs of at least one AL pack and individual stock-outs for each AL pack. Monthly proportions and summary means of the proportions over the monitoring period were measured for each indicator. Stock-out trends were assessed using linear regression. Results The number of surveyed facilities across 18 time points ranged between 162 and 176 facilities. The stock-out means of the proportion of health facilities were 11.6% for total AL stock-out, 40.6% for stock-out of at least one AL pack, and between 20.5% and 27.4% for stock-outs of individual AL packs. Monthly decrease of the total AL stock-out was 0.005% (95% CI: -0.5 to +0.5; p = 0.983). Monthly decrease in the stock-out of at least one AL pack was 0.7% (95% CI: -1.5 to +0.3; p = 0.058) while stock-outs of individual AL packs decreased monthly between 0.2% for AL 24-pack and 0.7% for AL six-pack without statistical significance for any of the weight-specific packs. Conclusions Despite lower levels of AL stock-outs compared to the reports in 2008, the stock-outs at Kenyan facilities during 2010-2011 are still substantial and of particular worry for the most detrimental:- simultaneous absence of any AL pack. Only minor decrease was observed in the stock-outs of individual AL packs. Recently launched ... |
format |
Article in Journal/Newspaper |
author |
Sudoi Raymond K Githinji Sophie Nyandigisi Andrew Muturi Alex Snow Robert W Zurovac Dejan |
author_facet |
Sudoi Raymond K Githinji Sophie Nyandigisi Andrew Muturi Alex Snow Robert W Zurovac Dejan |
author_sort |
Sudoi Raymond K |
title |
The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya |
title_short |
The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya |
title_full |
The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya |
title_fullStr |
The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya |
title_full_unstemmed |
The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya |
title_sort |
magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in kenya |
publisher |
BMC |
publishDate |
2012 |
url |
https://doi.org/10.1186/1475-2875-11-37 https://doaj.org/article/e093f9a27c5b434ea208c8d076c5efd3 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 11, Iss 1, p 37 (2012) |
op_relation |
http://www.malariajournal.com/content/11/1/37 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-37 1475-2875 https://doaj.org/article/e093f9a27c5b434ea208c8d076c5efd3 |
op_doi |
https://doi.org/10.1186/1475-2875-11-37 |
container_title |
Malaria Journal |
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11 |
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1 |
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37 |
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