Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish
Abstract Background Confined within the freezing Southern Ocean, the Antarctic notothenioids have evolved to become both cold adapted and cold specialized. A marked signature of cold specialization is an apparent loss of the cellular heat shock response (HSR). As the HSR has been examined in very fe...
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ftdoajarticles:oai:doaj.org/article:e037356fe41a4b9898f6d63de02ff84b 2023-05-15T13:44:03+02:00 Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish Kevin T. Bilyk Luis Vargas-Chacoff C.-H.Christina Cheng 2018-09-01T00:00:00Z https://doi.org/10.1186/s12862-018-1254-6 https://doaj.org/article/e037356fe41a4b9898f6d63de02ff84b EN eng BMC http://link.springer.com/article/10.1186/s12862-018-1254-6 https://doaj.org/toc/1471-2148 doi:10.1186/s12862-018-1254-6 1471-2148 https://doaj.org/article/e037356fe41a4b9898f6d63de02ff84b BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-16 (2018) Antarctic fish Notothenioid Cold-specialization Cellular stress response Stenothermal Thermal stress Evolution QH359-425 article 2018 ftdoajarticles https://doi.org/10.1186/s12862-018-1254-6 2022-12-31T07:19:43Z Abstract Background Confined within the freezing Southern Ocean, the Antarctic notothenioids have evolved to become both cold adapted and cold specialized. A marked signature of cold specialization is an apparent loss of the cellular heat shock response (HSR). As the HSR has been examined in very few notothenioid species to-date, it remains unknown whether HSR loss pervades the Antarctic radiation, or whether the broader cellular responses to heat stress has sustained similar loss. Understanding the evolutionary status of these responses in this stenothermal taxon is crucial for evaluating its adaptive potential to ocean warming under climate change. Results In this study, we used an acute heat stress protocol followed by RNA-Seq analyses to study the evolution of cellular-wide transcriptional responses to heat stress across three select notothenioid lineages - the basal temperate and nearest non-Antarctic sister species Eleginops maclovinus serving as ancestral proxy, the cryopelagic Pagothenia borchgrevinki and the icefish Chionodraco rastrospinosus representing cold-adapted red-blooded and hemoglobinless Antarctic notothenioids respectively. E. maclovinus displayed robust cellular stress responses including the ER Unfolded Protein Response and the cytosolic HSR, cementing the HSR as a plesiomorphy that preceded Antarctic notothenioid radiation. While the transcriptional response to heat stress was minimal in P. borchgrevinki, C. rastrospinosus exhibited robust responses in the broader cellular networks especially in inflammatory responses despite lacking the classic HSR and UPR. Conclusion The disparate patterns observed in these two archetypal Antarctic species indicate the evolutionary status in cellular ability to mitigate acute heat stress varies even among Antarctic lineages, which may affect their adaptive potential in coping with a warming world. Article in Journal/Newspaper Antarc* Antarctic Icefish Southern Ocean Directory of Open Access Journals: DOAJ Articles Antarctic Southern Ocean The Antarctic BMC Evolutionary Biology 18 1 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Antarctic fish Notothenioid Cold-specialization Cellular stress response Stenothermal Thermal stress Evolution QH359-425 |
spellingShingle |
Antarctic fish Notothenioid Cold-specialization Cellular stress response Stenothermal Thermal stress Evolution QH359-425 Kevin T. Bilyk Luis Vargas-Chacoff C.-H.Christina Cheng Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
topic_facet |
Antarctic fish Notothenioid Cold-specialization Cellular stress response Stenothermal Thermal stress Evolution QH359-425 |
description |
Abstract Background Confined within the freezing Southern Ocean, the Antarctic notothenioids have evolved to become both cold adapted and cold specialized. A marked signature of cold specialization is an apparent loss of the cellular heat shock response (HSR). As the HSR has been examined in very few notothenioid species to-date, it remains unknown whether HSR loss pervades the Antarctic radiation, or whether the broader cellular responses to heat stress has sustained similar loss. Understanding the evolutionary status of these responses in this stenothermal taxon is crucial for evaluating its adaptive potential to ocean warming under climate change. Results In this study, we used an acute heat stress protocol followed by RNA-Seq analyses to study the evolution of cellular-wide transcriptional responses to heat stress across three select notothenioid lineages - the basal temperate and nearest non-Antarctic sister species Eleginops maclovinus serving as ancestral proxy, the cryopelagic Pagothenia borchgrevinki and the icefish Chionodraco rastrospinosus representing cold-adapted red-blooded and hemoglobinless Antarctic notothenioids respectively. E. maclovinus displayed robust cellular stress responses including the ER Unfolded Protein Response and the cytosolic HSR, cementing the HSR as a plesiomorphy that preceded Antarctic notothenioid radiation. While the transcriptional response to heat stress was minimal in P. borchgrevinki, C. rastrospinosus exhibited robust responses in the broader cellular networks especially in inflammatory responses despite lacking the classic HSR and UPR. Conclusion The disparate patterns observed in these two archetypal Antarctic species indicate the evolutionary status in cellular ability to mitigate acute heat stress varies even among Antarctic lineages, which may affect their adaptive potential in coping with a warming world. |
format |
Article in Journal/Newspaper |
author |
Kevin T. Bilyk Luis Vargas-Chacoff C.-H.Christina Cheng |
author_facet |
Kevin T. Bilyk Luis Vargas-Chacoff C.-H.Christina Cheng |
author_sort |
Kevin T. Bilyk |
title |
Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
title_short |
Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
title_full |
Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
title_fullStr |
Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
title_full_unstemmed |
Evolution in chronic cold: varied loss of cellular response to heat in Antarctic notothenioid fish |
title_sort |
evolution in chronic cold: varied loss of cellular response to heat in antarctic notothenioid fish |
publisher |
BMC |
publishDate |
2018 |
url |
https://doi.org/10.1186/s12862-018-1254-6 https://doaj.org/article/e037356fe41a4b9898f6d63de02ff84b |
geographic |
Antarctic Southern Ocean The Antarctic |
geographic_facet |
Antarctic Southern Ocean The Antarctic |
genre |
Antarc* Antarctic Icefish Southern Ocean |
genre_facet |
Antarc* Antarctic Icefish Southern Ocean |
op_source |
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-16 (2018) |
op_relation |
http://link.springer.com/article/10.1186/s12862-018-1254-6 https://doaj.org/toc/1471-2148 doi:10.1186/s12862-018-1254-6 1471-2148 https://doaj.org/article/e037356fe41a4b9898f6d63de02ff84b |
op_doi |
https://doi.org/10.1186/s12862-018-1254-6 |
container_title |
BMC Evolutionary Biology |
container_volume |
18 |
container_issue |
1 |
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1766196418404417536 |