CLINICAL ASPECTS OF THE POISONING BY THE PESTICIDE ENDOSULFAN
Endosulfan is an organochlorine insecticide, widely used in insect control. Unfortunately, it is also an acute neurotoxic compound to both insects and mammals, including humans, and has been responsible for many severe poisonings and several fatal cases. Endosulfan also imitates or enhances the effe...
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ftdoajarticles:oai:doaj.org/article:dfdb8f36dd1441fdbda856dc48c5f3a4 2023-05-15T15:07:09+02:00 CLINICAL ASPECTS OF THE POISONING BY THE PESTICIDE ENDOSULFAN Jiří Patočka Qinghua Wu Tanos C. C. França Teodorico C. Ramalho Rene Pita Kamil Kuča https://doi.org/10.5935/0100-4042.20160102 https://doaj.org/article/dfdb8f36dd1441fdbda856dc48c5f3a4 EN ES PT eng spa por Sociedade Brasileira de Química http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422016000800987&lng=en&tlng=en https://doaj.org/toc/1678-7064 1678-7064 doi:10.5935/0100-4042.20160102 https://doaj.org/article/dfdb8f36dd1441fdbda856dc48c5f3a4 Química Nova, Vol 39, Iss 8, Pp 987-994 endosulfan organochlorine insecticides hazardous substance hormonal disruptor health hazard Chemistry QD1-999 article ftdoajarticles https://doi.org/10.5935/0100-4042.20160102 2022-12-31T14:38:00Z Endosulfan is an organochlorine insecticide, widely used in insect control. Unfortunately, it is also an acute neurotoxic compound to both insects and mammals, including humans, and has been responsible for many severe poisonings and several fatal cases. Endosulfan also imitates or enhances the effect of the female hormone estrogen, having the capability of causing reproductive and developmental damage in both, animals and humans, and its exposure has been linked to liver tissue injury. This persistent lipophilic compound is one of the most abundant organochlorine pesticides in the environment, capable of undergoing long range transport to remote locations such as the Arctic. It is practically water-insoluble, but readily adheres to clay particles and persists in soil and water for several years. Its indiscriminate and injudicious use in the control of insects on a wide range of agricultural products and in the extermination of house-hold pests, has considerably increased the hazard risk for human health. Also, this compound has a high fatality rate in humans when ingested accidentally, from food or water contaminated, or in suicidal cases. The aim of this article is to review and summarize chemical, biochemical, environmental, and toxicological data of endosulfan and draw attention to its toxicological potential risk to human health. Article in Journal/Newspaper Arctic Human health Directory of Open Access Journals: DOAJ Articles Arctic Química Nova |
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English Spanish Portuguese |
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endosulfan organochlorine insecticides hazardous substance hormonal disruptor health hazard Chemistry QD1-999 |
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endosulfan organochlorine insecticides hazardous substance hormonal disruptor health hazard Chemistry QD1-999 Jiří Patočka Qinghua Wu Tanos C. C. França Teodorico C. Ramalho Rene Pita Kamil Kuča CLINICAL ASPECTS OF THE POISONING BY THE PESTICIDE ENDOSULFAN |
topic_facet |
endosulfan organochlorine insecticides hazardous substance hormonal disruptor health hazard Chemistry QD1-999 |
description |
Endosulfan is an organochlorine insecticide, widely used in insect control. Unfortunately, it is also an acute neurotoxic compound to both insects and mammals, including humans, and has been responsible for many severe poisonings and several fatal cases. Endosulfan also imitates or enhances the effect of the female hormone estrogen, having the capability of causing reproductive and developmental damage in both, animals and humans, and its exposure has been linked to liver tissue injury. This persistent lipophilic compound is one of the most abundant organochlorine pesticides in the environment, capable of undergoing long range transport to remote locations such as the Arctic. It is practically water-insoluble, but readily adheres to clay particles and persists in soil and water for several years. Its indiscriminate and injudicious use in the control of insects on a wide range of agricultural products and in the extermination of house-hold pests, has considerably increased the hazard risk for human health. Also, this compound has a high fatality rate in humans when ingested accidentally, from food or water contaminated, or in suicidal cases. The aim of this article is to review and summarize chemical, biochemical, environmental, and toxicological data of endosulfan and draw attention to its toxicological potential risk to human health. |
format |
Article in Journal/Newspaper |
author |
Jiří Patočka Qinghua Wu Tanos C. C. França Teodorico C. Ramalho Rene Pita Kamil Kuča |
author_facet |
Jiří Patočka Qinghua Wu Tanos C. C. França Teodorico C. Ramalho Rene Pita Kamil Kuča |
author_sort |
Jiří Patočka |
title |
CLINICAL ASPECTS OF THE POISONING BY THE PESTICIDE ENDOSULFAN |
title_short |
CLINICAL ASPECTS OF THE POISONING BY THE PESTICIDE ENDOSULFAN |
title_full |
CLINICAL ASPECTS OF THE POISONING BY THE PESTICIDE ENDOSULFAN |
title_fullStr |
CLINICAL ASPECTS OF THE POISONING BY THE PESTICIDE ENDOSULFAN |
title_full_unstemmed |
CLINICAL ASPECTS OF THE POISONING BY THE PESTICIDE ENDOSULFAN |
title_sort |
clinical aspects of the poisoning by the pesticide endosulfan |
publisher |
Sociedade Brasileira de Química |
url |
https://doi.org/10.5935/0100-4042.20160102 https://doaj.org/article/dfdb8f36dd1441fdbda856dc48c5f3a4 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Human health |
genre_facet |
Arctic Human health |
op_source |
Química Nova, Vol 39, Iss 8, Pp 987-994 |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422016000800987&lng=en&tlng=en https://doaj.org/toc/1678-7064 1678-7064 doi:10.5935/0100-4042.20160102 https://doaj.org/article/dfdb8f36dd1441fdbda856dc48c5f3a4 |
op_doi |
https://doi.org/10.5935/0100-4042.20160102 |
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Química Nova |
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