Identification of anti-flaviviral drugs with mosquitocidal and anti-Zika virus activity in Aedes aegypti.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Shengzhang Dong, Seokyoung Kang, George Dimopoulos
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2019
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Barré
• Online Access: https://doi.org/10.1371/journal.pntd.0007681; https://doaj.org/article/df892d7a6c4f46e2959039e187f8cf0e

Zika virus (ZIKV), an emerging arbovirus belonging to the genus Flavivirus, is transmitted by Aedes mosquitoes. ZIKV infection can cause microcephaly of newborn babies and Guillain-Barré syndrome in adults. Because no licensed vaccine or specific antiviral treatment is available for ZIKV infection,...