A common error in the ecological regression of cancer incidence on the deprivation index
OBJECTIVE: To determine if introducing age as another explanatory variable in an ecological regression model relating crude rates of cancer incidence and a deprivation index provides better results than the usual practice of using the standard incidence ratio (SIR) as the response variable, introduc...
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ftdoajarticles:oai:doaj.org/article:debfcc7047174b14b74b239a031f0288 2023-05-15T15:11:23+02:00 A common error in the ecological regression of cancer incidence on the deprivation index Gemma Renart Marc Saez Carme Saurina Rafael Marcos-Gragera Ricardo Ocaña-Riola Carmen Martos Maria A. Barceló Federico Arribas Tomás Alcalá 2013-08-01T00:00:00Z https://doaj.org/article/debfcc7047174b14b74b239a031f0288 EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892013000800002&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 https://doaj.org/article/debfcc7047174b14b74b239a031f0288 Revista Panamericana de Salud Pública, Vol 34, Iss 2, Pp 83-91 (2013) Incidencia análisis espacial riesgo España Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2013 ftdoajarticles 2022-12-31T10:52:33Z OBJECTIVE: To determine if introducing age as another explanatory variable in an ecological regression model relating crude rates of cancer incidence and a deprivation index provides better results than the usual practice of using the standard incidence ratio (SIR) as the response variable, introducing the non-standardized index, and not including age in the model. METHODS: Relative risks associated with the deprivation index for some locations of cancer in Spain's Girona Health Region were estimated using two different models. Model 1 estimated relative risks with the indirect method, using the SIR as the response variable. Model 2 estimated relative risks using age as an explanatory variable and crude cancer rates as the response variable. Two scenarios and two sub-scenarios were simulated to test the properties of the estimators and the goodness of fit of the two models. RESULTS: The results obtained from Model 2's estimates were slightly better (less biased) than those from Model 1. The results of the simulation showed that in all cases (two scenarios and two sub-scenarios) Model 2 had a better fit than Model 1. The probability density for the parameter of interest provided evidence that Model 1 leads to biased estimates. CONCLUSIONS: When attempting to explain the relative risk of incidence of cancer using ecological models that control geographic variability, introducing age as another explanatory variable and crude rates as a response variable provides less biased results. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish Portuguese |
topic |
Incidencia análisis espacial riesgo España Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Incidencia análisis espacial riesgo España Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Gemma Renart Marc Saez Carme Saurina Rafael Marcos-Gragera Ricardo Ocaña-Riola Carmen Martos Maria A. Barceló Federico Arribas Tomás Alcalá A common error in the ecological regression of cancer incidence on the deprivation index |
topic_facet |
Incidencia análisis espacial riesgo España Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
OBJECTIVE: To determine if introducing age as another explanatory variable in an ecological regression model relating crude rates of cancer incidence and a deprivation index provides better results than the usual practice of using the standard incidence ratio (SIR) as the response variable, introducing the non-standardized index, and not including age in the model. METHODS: Relative risks associated with the deprivation index for some locations of cancer in Spain's Girona Health Region were estimated using two different models. Model 1 estimated relative risks with the indirect method, using the SIR as the response variable. Model 2 estimated relative risks using age as an explanatory variable and crude cancer rates as the response variable. Two scenarios and two sub-scenarios were simulated to test the properties of the estimators and the goodness of fit of the two models. RESULTS: The results obtained from Model 2's estimates were slightly better (less biased) than those from Model 1. The results of the simulation showed that in all cases (two scenarios and two sub-scenarios) Model 2 had a better fit than Model 1. The probability density for the parameter of interest provided evidence that Model 1 leads to biased estimates. CONCLUSIONS: When attempting to explain the relative risk of incidence of cancer using ecological models that control geographic variability, introducing age as another explanatory variable and crude rates as a response variable provides less biased results. |
format |
Article in Journal/Newspaper |
author |
Gemma Renart Marc Saez Carme Saurina Rafael Marcos-Gragera Ricardo Ocaña-Riola Carmen Martos Maria A. Barceló Federico Arribas Tomás Alcalá |
author_facet |
Gemma Renart Marc Saez Carme Saurina Rafael Marcos-Gragera Ricardo Ocaña-Riola Carmen Martos Maria A. Barceló Federico Arribas Tomás Alcalá |
author_sort |
Gemma Renart |
title |
A common error in the ecological regression of cancer incidence on the deprivation index |
title_short |
A common error in the ecological regression of cancer incidence on the deprivation index |
title_full |
A common error in the ecological regression of cancer incidence on the deprivation index |
title_fullStr |
A common error in the ecological regression of cancer incidence on the deprivation index |
title_full_unstemmed |
A common error in the ecological regression of cancer incidence on the deprivation index |
title_sort |
common error in the ecological regression of cancer incidence on the deprivation index |
publisher |
Pan American Health Organization |
publishDate |
2013 |
url |
https://doaj.org/article/debfcc7047174b14b74b239a031f0288 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 34, Iss 2, Pp 83-91 (2013) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892013000800002&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 https://doaj.org/article/debfcc7047174b14b74b239a031f0288 |
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1766342243725082624 |