Samsum ant venom modulates the immune response and redox status at the acute toxic dose in vivo

• Published in: Journal of Venomous Animals and Toxins including Tropical Diseases
• Main Authors: Hossam Ebaid, Bahaa Abdel-Salam, Ibrahim Alhazza, Jameel Al-Tamimi, Iftekhar Hassan, Ahmed Rady, Ashraf Mashaly, Ahmed Mahmoud, Reda Sammour
• Format: Article in Journal/Newspaper
• Language: English
• Published: SciELO
• Subjects: Samsum ant venom; Polymorphonuclear cells (PMNs); Costimulatory molecules (CD80 and CD86); Major histocompatibility complex (MHC); MHC-II; Interferon gamma (INF-γ); Interleukin-17 (IL-17); Arctic medicine. Tropical medicine; RC955-962; Toxicology. Poisons; RA1190-1270; Zoology; QL1-991; Arctic; Sav’
• Online Access: https://doi.org/10.1590/1678-9199-jvatitd-2019-0020; https://doaj.org/article/de56a1461719409cb0e2b4307e1b22a6

Abstract Background: Ant venoms express surface molecules that participate in antigen presentation involving pro- and anti-inflammatory cytokines. This work aims to investigate the expression of MHC-II, CD80 and CD86 on the polymorphonuclear cells (PMNs) in rats injected with samsum ant venom (SAV)....