Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period.
BACKGROUND:Rapid reinfestation of insecticide-treated dwellings hamper the sustained elimination of Triatoma infestans, the main vector of Chagas disease in the Gran Chaco region. We conducted a seven-year longitudinal study including community-wide spraying with pyrethroid insecticides combined wit...
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ftdoajarticles:oai:doaj.org/article:dde0dbc7558344c188a9535086330e71 2023-05-15T15:11:48+02:00 Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period. M Sol Gaspe Yael M Provecho María P Fernández Claudia V Vassena Pablo L Santo Orihuela Ricardo E Gürtler 2018-10-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0006804 https://doaj.org/article/dde0dbc7558344c188a9535086330e71 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC6168123?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006804 https://doaj.org/article/dde0dbc7558344c188a9535086330e71 PLoS Neglected Tropical Diseases, Vol 12, Iss 10, p e0006804 (2018) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2018 ftdoajarticles https://doi.org/10.1371/journal.pntd.0006804 2022-12-31T01:45:15Z BACKGROUND:Rapid reinfestation of insecticide-treated dwellings hamper the sustained elimination of Triatoma infestans, the main vector of Chagas disease in the Gran Chaco region. We conducted a seven-year longitudinal study including community-wide spraying with pyrethroid insecticides combined with periodic vector surveillance to investigate the house reinfestation process in connection with baseline pyrethroid resistance, housing quality and household mobility in a rural section of Pampa del Indio mainly inhabited by deprived indigenous people (Qom). METHODOLOGY/PRINCIPAL FINDINGS:Despite evidence of moderate pyrethroid resistance in local T. infestans populations, house infestation dropped from 31.9% at baseline to 0.7% at 10 months post-spraying (MPS), with no triatomine found at 59 and 78 MPS. Household-based surveillance corroborated the rare occurrence of T. infestans and the house invasion of other four triatomine species. The annual rates of loss of initially occupied houses and of household mobility were high (4.6-8.0%). Housing improvements did not translate into a significant reduction of mud-walled houses and refuges for triatomines because most households kept the former dwelling or built new ones with mud walls. CONCLUSIONS/SIGNIFICANCE:Our results refute the assumption that vector control actions performed in marginalized communities of the Gran Chaco are doomed to fail. The larger-than-expected impacts of the intervention program were likely associated with the combined effects of high-coverage, professional insecticide spraying followed by systematic vector surveillance-and-response, broad geographic coverage creating a buffer zone, frequent housing replacement and residential mobility. The dynamical interactions among housing quality, mobility and insecticide-based control largely affect the chances of vector elimination. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Argentine Chaco ENVELOPE(-60.583,-60.583,-63.033,-63.033) Pampa ENVELOPE(-57.216,-57.216,-63.883,-63.883) PLOS Neglected Tropical Diseases 12 10 e0006804 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 M Sol Gaspe Yael M Provecho María P Fernández Claudia V Vassena Pablo L Santo Orihuela Ricardo E Gürtler Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:Rapid reinfestation of insecticide-treated dwellings hamper the sustained elimination of Triatoma infestans, the main vector of Chagas disease in the Gran Chaco region. We conducted a seven-year longitudinal study including community-wide spraying with pyrethroid insecticides combined with periodic vector surveillance to investigate the house reinfestation process in connection with baseline pyrethroid resistance, housing quality and household mobility in a rural section of Pampa del Indio mainly inhabited by deprived indigenous people (Qom). METHODOLOGY/PRINCIPAL FINDINGS:Despite evidence of moderate pyrethroid resistance in local T. infestans populations, house infestation dropped from 31.9% at baseline to 0.7% at 10 months post-spraying (MPS), with no triatomine found at 59 and 78 MPS. Household-based surveillance corroborated the rare occurrence of T. infestans and the house invasion of other four triatomine species. The annual rates of loss of initially occupied houses and of household mobility were high (4.6-8.0%). Housing improvements did not translate into a significant reduction of mud-walled houses and refuges for triatomines because most households kept the former dwelling or built new ones with mud walls. CONCLUSIONS/SIGNIFICANCE:Our results refute the assumption that vector control actions performed in marginalized communities of the Gran Chaco are doomed to fail. The larger-than-expected impacts of the intervention program were likely associated with the combined effects of high-coverage, professional insecticide spraying followed by systematic vector surveillance-and-response, broad geographic coverage creating a buffer zone, frequent housing replacement and residential mobility. The dynamical interactions among housing quality, mobility and insecticide-based control largely affect the chances of vector elimination. |
format |
Article in Journal/Newspaper |
author |
M Sol Gaspe Yael M Provecho María P Fernández Claudia V Vassena Pablo L Santo Orihuela Ricardo E Gürtler |
author_facet |
M Sol Gaspe Yael M Provecho María P Fernández Claudia V Vassena Pablo L Santo Orihuela Ricardo E Gürtler |
author_sort |
M Sol Gaspe |
title |
Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period. |
title_short |
Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period. |
title_full |
Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period. |
title_fullStr |
Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period. |
title_full_unstemmed |
Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period. |
title_sort |
beating the odds: sustained chagas disease vector control in remote indigenous communities of the argentine chaco over a seven-year period. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2018 |
url |
https://doi.org/10.1371/journal.pntd.0006804 https://doaj.org/article/dde0dbc7558344c188a9535086330e71 |
long_lat |
ENVELOPE(-60.583,-60.583,-63.033,-63.033) ENVELOPE(-57.216,-57.216,-63.883,-63.883) |
geographic |
Arctic Argentine Chaco Pampa |
geographic_facet |
Arctic Argentine Chaco Pampa |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 12, Iss 10, p e0006804 (2018) |
op_relation |
http://europepmc.org/articles/PMC6168123?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006804 https://doaj.org/article/dde0dbc7558344c188a9535086330e71 |
op_doi |
https://doi.org/10.1371/journal.pntd.0006804 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
12 |
container_issue |
10 |
container_start_page |
e0006804 |
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1766342593373798400 |