Complement receptor 1 polymorphisms associated with resistance to severe malaria in Kenya

• Published in: Malaria Journal
• Main Authors: Otieno Walter, Guyah Bernard, Moulds JoAnn M, Thathy Vandana, Stoute José A
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2005
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; McCoy
• Online Access: https://doi.org/10.1186/1475-2875-4-54; https://doaj.org/article/ddace73fa03143a5bd02468633afb09d

Abstract Background It has been hypothesized that the African alleles Sl2 and McC b of the Swain-Langley (Sl) and McCoy (McC) blood group antigens of the complement receptor 1 (CR1) may confer a survival advantage in the setting of Plasmodium falciparum malaria, but this has not been demonstrated. M...