Qualitative and Quantitative Evaluation of Rosavin, Salidroside, and p-Tyrosol in Artic Root Products via TLC-Screening, HPLC-DAD, and NMR Spectroscopy

Artic root is a well-known plant adaptogen with multipotential pharmacological properties. Thin-layer chromatography (TLC)—screening followed by diode-array high-performance liquid chromatography and nuclear magnetic resonance spectroscopy proved to be a reliable and convenient method for the simult...

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Bibliographic Details
Published in:Molecules
Main Authors: Hanna Nikolaichuk, Marek Studziński, Marek Stankevič, Irena M. Choma
Format: Article in Journal/Newspaper
Language:English
Published: MDPI AG 2022
Subjects:
TLC-screening
HPLC-DAD
NMR
arctic root
Organic chemistry
QD241-441
Arctic
Online Access:https://doi.org/10.3390/molecules27238299
https://doaj.org/article/dda89217d33545a6a7b834c507dc21ca
Description
Summary:Artic root is a well-known plant adaptogen with multipotential pharmacological properties. Thin-layer chromatography (TLC)—screening followed by diode-array high-performance liquid chromatography and nuclear magnetic resonance spectroscopy proved to be a reliable and convenient method for the simultaneous determination of the quality of various herbal raw materials and supplements. This combination allowed for comparing and differentiating arctic root samples as well as defining their authenticity. The study provided information on the chemical and biological properties of the seven chosen samples as well as qualitative and quantitative evaluation of the quality markers: rosavin, salidroside, and p-tyrosol. The absence of rosavin, salidroside, and p-tyrosol in three samples was detected using TLC screening and confirmed by HPLC-DAD and NMR. The paper highlighted the importance of quality control and strict regulation for herbal medicine supplements and preparations.

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