Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort
Abstract Background Dietary patterns are commonly used in epidemiological research, yet there have been few studies assessing if and how research results may vary across dietary patterns. This study aimed to estimate the risk of mortality/recurrence/metastasis using different dietary patterns and co...
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ftdoajarticles:oai:doaj.org/article:dd2e675a1dcc4ac98735637933552273 2023-05-15T17:21:55+02:00 Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort Ishor Sharma Barbara Roebothan Yun Zhu Jennifer Woodrow Patrick S. Parfrey John R. Mclaughlin Peter Peizhong Wang 2018-05-01T00:00:00Z https://doi.org/10.1186/s12937-018-0362-x https://doaj.org/article/dd2e675a1dcc4ac98735637933552273 EN eng BMC http://link.springer.com/article/10.1186/s12937-018-0362-x https://doaj.org/toc/1475-2891 doi:10.1186/s12937-018-0362-x 1475-2891 https://doaj.org/article/dd2e675a1dcc4ac98735637933552273 Nutrition Journal, Vol 17, Iss 1, Pp 1-9 (2018) Colorectal Cancer Dietary patterns Factor analysis Cluster analysis Index analysis Nutrition. Foods and food supply TX341-641 Nutritional diseases. Deficiency diseases RC620-627 article 2018 ftdoajarticles https://doi.org/10.1186/s12937-018-0362-x 2022-12-31T13:52:37Z Abstract Background Dietary patterns are commonly used in epidemiological research, yet there have been few studies assessing if and how research results may vary across dietary patterns. This study aimed to estimate the risk of mortality/recurrence/metastasis using different dietary patterns and comparison amongst the patterns. Methods Dietary patterns were identified by Cluster Analysis (CA), Principal Component Analysis (PCA), Alternate Mediterranean Diet score (altMED), Recommended Food Score (RFS) and Dietary Inflammatory Index (DII) scores using a 169-item food frequency questionnaire. Five hundred thirty-two colorectal cancer patients diagnosed between 1999 and 2003 in Newfoundland were followed-up until 2010. Overall Mortality (OM) and combined Mortality, Recurrence or Metastasis (cMRM) were identified. Comparisons were made with adjusted Cox proportional Hazards Ratios (HRs), correlation coefficients and the distributions of individuals in defined clusters by quartiles of factor and index scores. Results One hundred and seventy cases died from all causes and 29 had a cancer recurrence/metastasis during follow-up. Processed meats as classified by PCA (HR 1.82; 95% confidence interval (CI) 1.07–3.09), clusters characterized by meat and dairy products (HR 2.19; 95% CI 1.03–4.67) and total grains, sugar, soft drinks (HR 1.95; 95% CI 1.13–3.37) were associated with a higher risk of cMRM. Poor adherence to AltMED increased the risk of all-cause OM (HR 1.62; 95% CI 1.04–2.56). Prudent vegetable, high sugar pattern, RFS and DII had no significant association with both OM and cMRM. Conclusion Estimation of OM and cMRM varied across dietary patterns which is attributed to the differences in the foundation of each pattern. Article in Journal/Newspaper Newfoundland Directory of Open Access Journals: DOAJ Articles Newfoundland Nutrition Journal 17 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Colorectal Cancer Dietary patterns Factor analysis Cluster analysis Index analysis Nutrition. Foods and food supply TX341-641 Nutritional diseases. Deficiency diseases RC620-627 |
spellingShingle |
Colorectal Cancer Dietary patterns Factor analysis Cluster analysis Index analysis Nutrition. Foods and food supply TX341-641 Nutritional diseases. Deficiency diseases RC620-627 Ishor Sharma Barbara Roebothan Yun Zhu Jennifer Woodrow Patrick S. Parfrey John R. Mclaughlin Peter Peizhong Wang Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort |
topic_facet |
Colorectal Cancer Dietary patterns Factor analysis Cluster analysis Index analysis Nutrition. Foods and food supply TX341-641 Nutritional diseases. Deficiency diseases RC620-627 |
description |
Abstract Background Dietary patterns are commonly used in epidemiological research, yet there have been few studies assessing if and how research results may vary across dietary patterns. This study aimed to estimate the risk of mortality/recurrence/metastasis using different dietary patterns and comparison amongst the patterns. Methods Dietary patterns were identified by Cluster Analysis (CA), Principal Component Analysis (PCA), Alternate Mediterranean Diet score (altMED), Recommended Food Score (RFS) and Dietary Inflammatory Index (DII) scores using a 169-item food frequency questionnaire. Five hundred thirty-two colorectal cancer patients diagnosed between 1999 and 2003 in Newfoundland were followed-up until 2010. Overall Mortality (OM) and combined Mortality, Recurrence or Metastasis (cMRM) were identified. Comparisons were made with adjusted Cox proportional Hazards Ratios (HRs), correlation coefficients and the distributions of individuals in defined clusters by quartiles of factor and index scores. Results One hundred and seventy cases died from all causes and 29 had a cancer recurrence/metastasis during follow-up. Processed meats as classified by PCA (HR 1.82; 95% confidence interval (CI) 1.07–3.09), clusters characterized by meat and dairy products (HR 2.19; 95% CI 1.03–4.67) and total grains, sugar, soft drinks (HR 1.95; 95% CI 1.13–3.37) were associated with a higher risk of cMRM. Poor adherence to AltMED increased the risk of all-cause OM (HR 1.62; 95% CI 1.04–2.56). Prudent vegetable, high sugar pattern, RFS and DII had no significant association with both OM and cMRM. Conclusion Estimation of OM and cMRM varied across dietary patterns which is attributed to the differences in the foundation of each pattern. |
format |
Article in Journal/Newspaper |
author |
Ishor Sharma Barbara Roebothan Yun Zhu Jennifer Woodrow Patrick S. Parfrey John R. Mclaughlin Peter Peizhong Wang |
author_facet |
Ishor Sharma Barbara Roebothan Yun Zhu Jennifer Woodrow Patrick S. Parfrey John R. Mclaughlin Peter Peizhong Wang |
author_sort |
Ishor Sharma |
title |
Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort |
title_short |
Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort |
title_full |
Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort |
title_fullStr |
Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort |
title_full_unstemmed |
Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort |
title_sort |
hypothesis and data-driven dietary patterns and colorectal cancer survival: findings from newfoundland and labrador colorectal cancer cohort |
publisher |
BMC |
publishDate |
2018 |
url |
https://doi.org/10.1186/s12937-018-0362-x https://doaj.org/article/dd2e675a1dcc4ac98735637933552273 |
geographic |
Newfoundland |
geographic_facet |
Newfoundland |
genre |
Newfoundland |
genre_facet |
Newfoundland |
op_source |
Nutrition Journal, Vol 17, Iss 1, Pp 1-9 (2018) |
op_relation |
http://link.springer.com/article/10.1186/s12937-018-0362-x https://doaj.org/toc/1475-2891 doi:10.1186/s12937-018-0362-x 1475-2891 https://doaj.org/article/dd2e675a1dcc4ac98735637933552273 |
op_doi |
https://doi.org/10.1186/s12937-018-0362-x |
container_title |
Nutrition Journal |
container_volume |
17 |
container_issue |
1 |
_version_ |
1766107922949996544 |