The burden of parasitic zoonoses in Nepal: a systematic review.
Background Parasitic zoonoses (PZs) pose a significant but often neglected threat to public health, especially in developing countries. In order to obtain a better understanding of their health impact, summary measures of population health may be calculated, such as the Disability-Adjusted Life Year...
Published in: | PLoS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0002634 https://doaj.org/article/dc8574ac984b4f2ab6b6d14ef7eba30a |
id |
ftdoajarticles:oai:doaj.org/article:dc8574ac984b4f2ab6b6d14ef7eba30a |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:dc8574ac984b4f2ab6b6d14ef7eba30a 2023-05-15T15:13:35+02:00 The burden of parasitic zoonoses in Nepal: a systematic review. Brecht Devleesschauwer Anita Ale Paul Torgerson Nicolas Praet Charline Maertens de Noordhout Basu Dev Pandey Sher Bahadur Pun Rob Lake Jozef Vercruysse Durga Datt Joshi Arie H Havelaar Luc Duchateau Pierre Dorny Niko Speybroeck 2014-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0002634 https://doaj.org/article/dc8574ac984b4f2ab6b6d14ef7eba30a EN eng Public Library of Science (PLoS) https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24392178/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002634 https://doaj.org/article/dc8574ac984b4f2ab6b6d14ef7eba30a PLoS Neglected Tropical Diseases, Vol 8, Iss 1, p e2634 (2014) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2014 ftdoajarticles https://doi.org/10.1371/journal.pntd.0002634 2022-12-31T04:15:33Z Background Parasitic zoonoses (PZs) pose a significant but often neglected threat to public health, especially in developing countries. In order to obtain a better understanding of their health impact, summary measures of population health may be calculated, such as the Disability-Adjusted Life Year (DALY). However, the data required to calculate such measures are often not readily available for these diseases, which may lead to a vicious circle of under-recognition and under-funding. Methodology We examined the burden of PZs in Nepal through a systematic review of online and offline data sources. PZs were classified qualitatively according to endemicity, and where possible a quantitative burden assessment was conducted in terms of the annual number of incident cases, deaths and DALYs. Principal findings Between 2000 and 2012, the highest annual burden was imposed by neurocysticercosis and congenital toxoplasmosis (14,268 DALYs [95% Credibility Interval (CrI): 5450-27,694] and 9255 DALYs [95% CrI: 6135-13,292], respectively), followed by cystic echinococcosis (251 DALYs [95% CrI: 105-458]). Nepal is probably endemic for trichinellosis, toxocarosis, diphyllobothriosis, foodborne trematodosis, taeniosis, and zoonotic intestinal helminthic and protozoal infections, but insufficient data were available to quantify their health impact. Sporadic cases of alveolar echinococcosis, angiostrongylosis, capillariosis, dirofilariosis, gnathostomosis, sparganosis and cutaneous leishmaniosis may occur. Conclusions/significance In settings with limited surveillance capacity, it is possible to quantify the health impact of PZs and other neglected diseases, thereby interrupting the vicious circle of neglect. In Nepal, we found that several PZs are endemic and are imposing a significant burden to public health, higher than that of malaria, and comparable to that of HIV/AIDS. However, several critical data gaps remain. Enhanced surveillance for the endemic PZs identified in this study would enable additional burden estimates, and a ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Daly ENVELOPE(63.761,63.761,-67.513,-67.513) PLoS Neglected Tropical Diseases 8 1 e2634 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Brecht Devleesschauwer Anita Ale Paul Torgerson Nicolas Praet Charline Maertens de Noordhout Basu Dev Pandey Sher Bahadur Pun Rob Lake Jozef Vercruysse Durga Datt Joshi Arie H Havelaar Luc Duchateau Pierre Dorny Niko Speybroeck The burden of parasitic zoonoses in Nepal: a systematic review. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Parasitic zoonoses (PZs) pose a significant but often neglected threat to public health, especially in developing countries. In order to obtain a better understanding of their health impact, summary measures of population health may be calculated, such as the Disability-Adjusted Life Year (DALY). However, the data required to calculate such measures are often not readily available for these diseases, which may lead to a vicious circle of under-recognition and under-funding. Methodology We examined the burden of PZs in Nepal through a systematic review of online and offline data sources. PZs were classified qualitatively according to endemicity, and where possible a quantitative burden assessment was conducted in terms of the annual number of incident cases, deaths and DALYs. Principal findings Between 2000 and 2012, the highest annual burden was imposed by neurocysticercosis and congenital toxoplasmosis (14,268 DALYs [95% Credibility Interval (CrI): 5450-27,694] and 9255 DALYs [95% CrI: 6135-13,292], respectively), followed by cystic echinococcosis (251 DALYs [95% CrI: 105-458]). Nepal is probably endemic for trichinellosis, toxocarosis, diphyllobothriosis, foodborne trematodosis, taeniosis, and zoonotic intestinal helminthic and protozoal infections, but insufficient data were available to quantify their health impact. Sporadic cases of alveolar echinococcosis, angiostrongylosis, capillariosis, dirofilariosis, gnathostomosis, sparganosis and cutaneous leishmaniosis may occur. Conclusions/significance In settings with limited surveillance capacity, it is possible to quantify the health impact of PZs and other neglected diseases, thereby interrupting the vicious circle of neglect. In Nepal, we found that several PZs are endemic and are imposing a significant burden to public health, higher than that of malaria, and comparable to that of HIV/AIDS. However, several critical data gaps remain. Enhanced surveillance for the endemic PZs identified in this study would enable additional burden estimates, and a ... |
format |
Article in Journal/Newspaper |
author |
Brecht Devleesschauwer Anita Ale Paul Torgerson Nicolas Praet Charline Maertens de Noordhout Basu Dev Pandey Sher Bahadur Pun Rob Lake Jozef Vercruysse Durga Datt Joshi Arie H Havelaar Luc Duchateau Pierre Dorny Niko Speybroeck |
author_facet |
Brecht Devleesschauwer Anita Ale Paul Torgerson Nicolas Praet Charline Maertens de Noordhout Basu Dev Pandey Sher Bahadur Pun Rob Lake Jozef Vercruysse Durga Datt Joshi Arie H Havelaar Luc Duchateau Pierre Dorny Niko Speybroeck |
author_sort |
Brecht Devleesschauwer |
title |
The burden of parasitic zoonoses in Nepal: a systematic review. |
title_short |
The burden of parasitic zoonoses in Nepal: a systematic review. |
title_full |
The burden of parasitic zoonoses in Nepal: a systematic review. |
title_fullStr |
The burden of parasitic zoonoses in Nepal: a systematic review. |
title_full_unstemmed |
The burden of parasitic zoonoses in Nepal: a systematic review. |
title_sort |
burden of parasitic zoonoses in nepal: a systematic review. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doi.org/10.1371/journal.pntd.0002634 https://doaj.org/article/dc8574ac984b4f2ab6b6d14ef7eba30a |
long_lat |
ENVELOPE(63.761,63.761,-67.513,-67.513) |
geographic |
Arctic Daly |
geographic_facet |
Arctic Daly |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 8, Iss 1, p e2634 (2014) |
op_relation |
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24392178/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002634 https://doaj.org/article/dc8574ac984b4f2ab6b6d14ef7eba30a |
op_doi |
https://doi.org/10.1371/journal.pntd.0002634 |
container_title |
PLoS Neglected Tropical Diseases |
container_volume |
8 |
container_issue |
1 |
container_start_page |
e2634 |
_version_ |
1766344123240939520 |