Emergence of bla NDM-1 associated with the aac(6’)-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil
Abstract INTRODUCTION: The emergence of New Delhi metallo-β-lactamase (NDM) is concernig because it reduces the antibiotic therapy options for bacterial infections. METHODS: Resistant and virulent genes from an isolate of Klebsiella pneumoniae derived from a patient with sepsis in a hospital in Reci...
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ftdoajarticles:oai:doaj.org/article:dc6a350b7bdf4480978f735e7b9f3c92 2023-05-15T15:03:03+02:00 Emergence of bla NDM-1 associated with the aac(6’)-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil Alexsandra Maria Lima Scavuzzi Elza Ferreira Firmo Érica Maria de Oliveira Ana Catarina de Souza Lopes 2019-05-01T00:00:00Z https://doi.org/10.1590/0037-8682-0352-2018 https://doaj.org/article/dc6a350b7bdf4480978f735e7b9f3c92 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100652&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0352-2018 https://doaj.org/article/dc6a350b7bdf4480978f735e7b9f3c92 Revista da Sociedade Brasileira de Medicina Tropical, Vol 52, Iss 0 (2019) bla NDM-1 Klebsiella pneumoniae Resistance Virulence Arctic medicine. Tropical medicine RC955-962 article 2019 ftdoajarticles https://doi.org/10.1590/0037-8682-0352-2018 2022-12-31T02:41:34Z Abstract INTRODUCTION: The emergence of New Delhi metallo-β-lactamase (NDM) is concernig because it reduces the antibiotic therapy options for bacterial infections. METHODS: Resistant and virulent genes from an isolate of Klebsiella pneumoniae derived from a patient with sepsis in a hospital in Recife-PE, Brazil, were investigated using PCR and DNA sequencing. RESULTS: bla NDM-1, aac(6’)-Ib-cr and acrB resistance genes, and cps and mrkD virulence genes were detected. CONCLUSIONS To our knowledge, this is the first report on bla NDM-1 in Recife-PE. This detection alerts researchers to the need to control the spread of bla NDM-1 resistance gene by this bacterium in Brazil. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 52 |
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English |
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bla NDM-1 Klebsiella pneumoniae Resistance Virulence Arctic medicine. Tropical medicine RC955-962 |
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bla NDM-1 Klebsiella pneumoniae Resistance Virulence Arctic medicine. Tropical medicine RC955-962 Alexsandra Maria Lima Scavuzzi Elza Ferreira Firmo Érica Maria de Oliveira Ana Catarina de Souza Lopes Emergence of bla NDM-1 associated with the aac(6’)-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil |
topic_facet |
bla NDM-1 Klebsiella pneumoniae Resistance Virulence Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION: The emergence of New Delhi metallo-β-lactamase (NDM) is concernig because it reduces the antibiotic therapy options for bacterial infections. METHODS: Resistant and virulent genes from an isolate of Klebsiella pneumoniae derived from a patient with sepsis in a hospital in Recife-PE, Brazil, were investigated using PCR and DNA sequencing. RESULTS: bla NDM-1, aac(6’)-Ib-cr and acrB resistance genes, and cps and mrkD virulence genes were detected. CONCLUSIONS To our knowledge, this is the first report on bla NDM-1 in Recife-PE. This detection alerts researchers to the need to control the spread of bla NDM-1 resistance gene by this bacterium in Brazil. |
format |
Article in Journal/Newspaper |
author |
Alexsandra Maria Lima Scavuzzi Elza Ferreira Firmo Érica Maria de Oliveira Ana Catarina de Souza Lopes |
author_facet |
Alexsandra Maria Lima Scavuzzi Elza Ferreira Firmo Érica Maria de Oliveira Ana Catarina de Souza Lopes |
author_sort |
Alexsandra Maria Lima Scavuzzi |
title |
Emergence of bla NDM-1 associated with the aac(6’)-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil |
title_short |
Emergence of bla NDM-1 associated with the aac(6’)-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil |
title_full |
Emergence of bla NDM-1 associated with the aac(6’)-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil |
title_fullStr |
Emergence of bla NDM-1 associated with the aac(6’)-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil |
title_full_unstemmed |
Emergence of bla NDM-1 associated with the aac(6’)-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil |
title_sort |
emergence of bla ndm-1 associated with the aac(6’)-ib-cr, acrb, cps, and mrkd genes in a clinical isolate of multi-drug resistant klebsiella pneumoniae from recife-pe, brazil |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2019 |
url |
https://doi.org/10.1590/0037-8682-0352-2018 https://doaj.org/article/dc6a350b7bdf4480978f735e7b9f3c92 |
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Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 52, Iss 0 (2019) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100652&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0352-2018 https://doaj.org/article/dc6a350b7bdf4480978f735e7b9f3c92 |
op_doi |
https://doi.org/10.1590/0037-8682-0352-2018 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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52 |
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