Schistosoma mansoni: evaluation of the activity of oxamniquine on schistosomules, at 24 hours after infection Schistosoma mansoni: avaliação da atividade da oxamniquina (Mansil*) em esquistossômulos com 24 horas após infecção

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: Paulo Marcos Zech Coelho, Rômulo Teixeira de Mello, Silvia Elizabeth Gerken
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 1993
• Subjects: Schistosoma mansoni; Oxamniquine; Schistosomules; Migration; Chemotherapeutic treatment; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Droga; The Portal
• Online Access: https://doi.org/10.1590/S0036-46651993000600013; https://doaj.org/article/dc10ee885ffb4747aeedc3dc3dfc8bdd

Mice transcutaneously infected with about 400 cercariae were submitted to treatment with oxamniquine (400 mg/kg), 24 hours after infection. The recovery of schistosomules, at 4, 24, 48 and 72 hours and 35 days after treatment, showed the activity of the drug on the parasites, thus practically preven...