Cystic echinococcosis in the Province of Álava, North Spain: the monetary burden of a disease no longer under surveillance.
Cystic echinococcosis (CE) is endemic in Spain but has been considered non-endemic in the province of Álava, Northern Spain, since 1997. However, Álava is surrounded by autonomous regions with some of the highest CE prevalence proportions in the nation, casting doubts about the current classificatio...
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ftdoajarticles:oai:doaj.org/article:dbee0fae258547538b0a9715ef72dde5 2023-05-15T15:14:08+02:00 Cystic echinococcosis in the Province of Álava, North Spain: the monetary burden of a disease no longer under surveillance. Hélène Carabin Francisco J Balsera-Rodríguez José Rebollar-Sáenz Christine T Benner Aitziber Benito Juan C Fernández-Crespo David Carmena 2014-08-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0003069 https://doaj.org/article/dbee0fae258547538b0a9715ef72dde5 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4125306?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003069 https://doaj.org/article/dbee0fae258547538b0a9715ef72dde5 PLoS Neglected Tropical Diseases, Vol 8, Iss 8, p e3069 (2014) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2014 ftdoajarticles https://doi.org/10.1371/journal.pntd.0003069 2022-12-31T12:37:29Z Cystic echinococcosis (CE) is endemic in Spain but has been considered non-endemic in the province of Álava, Northern Spain, since 1997. However, Álava is surrounded by autonomous regions with some of the highest CE prevalence proportions in the nation, casting doubts about the current classification. The purpose of this study is to estimate the frequency of CE in humans and animals and to use this data to determine the societal cost incurred due to CE in the Álava population in 2005. We have identified epidemiological and clinical data from surveillance and hospital records, prevalence data in intermediate (sheep and cattle) host species from abattoir records, and economical data from national and regional official institutions. Direct costs (diagnosis, treatment, medical care in humans and condemnation of offal in livestock species) and indirect costs (productivity losses in humans and reduction in growth, fecundity and milk production in livestock) were modelled using the Latin hypercube method under five different scenarios reflecting different assumptions regarding the prevalence of asymptomatic cases and associated productivity losses in humans. A total of 13 human CE cases were reported in 2005. The median total cost (95% credible interval) of CE in humans and animals in Álava in 2005 was estimated to range between €61,864 (95%CI%: €47,304-€76,590) and €360,466 (95%CI: €76,424-€752,469), with human-associated losses ranging from 57% to 93% of the total losses, depending on the scenario used. Our data provide evidence that CE is still very well present in Álava and incurs important cost to the province every year. We expect this information to prove valuable for public health agencies and policy-makers, as it seems advisable to reinstate appropriate surveillance and monitoring systems and to implement effective control measures that avoid the spread and recrudescence of the disease. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 8 8 e3069 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Hélène Carabin Francisco J Balsera-Rodríguez José Rebollar-Sáenz Christine T Benner Aitziber Benito Juan C Fernández-Crespo David Carmena Cystic echinococcosis in the Province of Álava, North Spain: the monetary burden of a disease no longer under surveillance. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Cystic echinococcosis (CE) is endemic in Spain but has been considered non-endemic in the province of Álava, Northern Spain, since 1997. However, Álava is surrounded by autonomous regions with some of the highest CE prevalence proportions in the nation, casting doubts about the current classification. The purpose of this study is to estimate the frequency of CE in humans and animals and to use this data to determine the societal cost incurred due to CE in the Álava population in 2005. We have identified epidemiological and clinical data from surveillance and hospital records, prevalence data in intermediate (sheep and cattle) host species from abattoir records, and economical data from national and regional official institutions. Direct costs (diagnosis, treatment, medical care in humans and condemnation of offal in livestock species) and indirect costs (productivity losses in humans and reduction in growth, fecundity and milk production in livestock) were modelled using the Latin hypercube method under five different scenarios reflecting different assumptions regarding the prevalence of asymptomatic cases and associated productivity losses in humans. A total of 13 human CE cases were reported in 2005. The median total cost (95% credible interval) of CE in humans and animals in Álava in 2005 was estimated to range between €61,864 (95%CI%: €47,304-€76,590) and €360,466 (95%CI: €76,424-€752,469), with human-associated losses ranging from 57% to 93% of the total losses, depending on the scenario used. Our data provide evidence that CE is still very well present in Álava and incurs important cost to the province every year. We expect this information to prove valuable for public health agencies and policy-makers, as it seems advisable to reinstate appropriate surveillance and monitoring systems and to implement effective control measures that avoid the spread and recrudescence of the disease. |
format |
Article in Journal/Newspaper |
author |
Hélène Carabin Francisco J Balsera-Rodríguez José Rebollar-Sáenz Christine T Benner Aitziber Benito Juan C Fernández-Crespo David Carmena |
author_facet |
Hélène Carabin Francisco J Balsera-Rodríguez José Rebollar-Sáenz Christine T Benner Aitziber Benito Juan C Fernández-Crespo David Carmena |
author_sort |
Hélène Carabin |
title |
Cystic echinococcosis in the Province of Álava, North Spain: the monetary burden of a disease no longer under surveillance. |
title_short |
Cystic echinococcosis in the Province of Álava, North Spain: the monetary burden of a disease no longer under surveillance. |
title_full |
Cystic echinococcosis in the Province of Álava, North Spain: the monetary burden of a disease no longer under surveillance. |
title_fullStr |
Cystic echinococcosis in the Province of Álava, North Spain: the monetary burden of a disease no longer under surveillance. |
title_full_unstemmed |
Cystic echinococcosis in the Province of Álava, North Spain: the monetary burden of a disease no longer under surveillance. |
title_sort |
cystic echinococcosis in the province of álava, north spain: the monetary burden of a disease no longer under surveillance. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doi.org/10.1371/journal.pntd.0003069 https://doaj.org/article/dbee0fae258547538b0a9715ef72dde5 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 8, Iss 8, p e3069 (2014) |
op_relation |
http://europepmc.org/articles/PMC4125306?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003069 https://doaj.org/article/dbee0fae258547538b0a9715ef72dde5 |
op_doi |
https://doi.org/10.1371/journal.pntd.0003069 |
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PLoS Neglected Tropical Diseases |
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8 |
container_issue |
8 |
container_start_page |
e3069 |
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