Risk factors and prevalence of antibodies against hepatitis A virus (HAV) in children from day-care centers, in Goiania, Brazil Fatores de risco e prevalência de anticorpos contra o vírus da hepatite A (VHA) em crianças de creche em Goiânia, Brasil
A seroepidemiologic survey about hepatitis A virus (HAV) infection was carried out in a group comprising 310 children, ranging in age from 3 months to 9 years, from day-care centers, in Goiania, a middle sized city in the central region of Brazil. The biomarkers employed in the investigation of prev...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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Universidade de São Paulo (USP)
1995
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ftdoajarticles:oai:doaj.org/article:dbafa76a2d5448c28d2181cdbcd3719a 2024-09-09T19:28:43+00:00 Risk factors and prevalence of antibodies against hepatitis A virus (HAV) in children from day-care centers, in Goiania, Brazil Fatores de risco e prevalência de anticorpos contra o vírus da hepatite A (VHA) em crianças de creche em Goiânia, Brasil D.A.O. Queiróz D.D.P. Cardoso C.M.T. Martelli R.M.B. Martins S.O.B. Porto A.M.T. Borges M.S.P. Azevedo R.R. Daher 1995-10-01T00:00:00Z https://doi.org/10.1590/S0036-46651995000500008 https://doaj.org/article/dbafa76a2d5448c28d2181cdbcd3719a EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651995000500008 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651995000500008 0036-4665 1678-9946 https://doaj.org/article/dbafa76a2d5448c28d2181cdbcd3719a Revista do Instituto de Medicina Tropical de São Paulo, Vol 37, Iss 5, Pp 427-433 (1995) Hepatitis A survey Seroepidemiology Day-care children Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1995 ftdoajarticles https://doi.org/10.1590/S0036-46651995000500008 2024-08-05T17:49:31Z A seroepidemiologic survey about hepatitis A virus (HAV) infection was carried out in a group comprising 310 children, ranging in age from 3 months to 9 years, from day-care centers, in Goiania, a middle sized city in the central region of Brazil. The biomarkers employed in the investigation of previous infection include total IgG and IgM anti-HAV antibodies, and for the detection of more recent infection, IgM anti-HAV antibodies were analyzed. The study was performed in 1991 and 1992. According to the results, 69.7% of the children presented total IgG/IgM anti-HAV antibodies, with 60% of the group in the age range of 1 to 3 years. Among 10 day-care centers analyzed, the prevalence of the biomarker IgM anti-HAV was 3.2%, with an uniform distribution of the cases in the group of children ranging in age from 1 to 4 years. Multi-variate analysis was performed to investigate the sociodemographic factors that could influence the results. It was verified that the risk for the infection increased with the length of the attendance in the day-care centers, i.e., the risk for children with attendance of one year or more was 4.7 times higher, when compared with children with one month attendance (CI 95% 2.3-9.9). According to the results, hepatitis A is an endemic infection in day-care centers in the study area. The length of attendance in the day-care settings was demonstrated to be a risk factor for the HAV infection. Such findings suggest that if hepatits A vaccination becomes available as a routine policy in our region, the target group should be children under one year. Moreover, those children should receive the vaccine before they start to attend the day-care centers. Um estudo soroepidemiológico para o vírus da hepatite A (VHA), investigando os marcadores de infecção passada (anti-VHA total - IgG e IgM) e infecção recente (anti-VHA IgM), foi realizado entre 1991 e 1992, em crianças de creche de Goiânia-Brasil central. Das 310 crianças com idade entre 03 meses e 09 anos, 69,7% mostraram soropositividade ao anti-VHA ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 37 5 427 433 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Hepatitis A survey Seroepidemiology Day-care children Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Hepatitis A survey Seroepidemiology Day-care children Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 D.A.O. Queiróz D.D.P. Cardoso C.M.T. Martelli R.M.B. Martins S.O.B. Porto A.M.T. Borges M.S.P. Azevedo R.R. Daher Risk factors and prevalence of antibodies against hepatitis A virus (HAV) in children from day-care centers, in Goiania, Brazil Fatores de risco e prevalência de anticorpos contra o vírus da hepatite A (VHA) em crianças de creche em Goiânia, Brasil |
topic_facet |
Hepatitis A survey Seroepidemiology Day-care children Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
A seroepidemiologic survey about hepatitis A virus (HAV) infection was carried out in a group comprising 310 children, ranging in age from 3 months to 9 years, from day-care centers, in Goiania, a middle sized city in the central region of Brazil. The biomarkers employed in the investigation of previous infection include total IgG and IgM anti-HAV antibodies, and for the detection of more recent infection, IgM anti-HAV antibodies were analyzed. The study was performed in 1991 and 1992. According to the results, 69.7% of the children presented total IgG/IgM anti-HAV antibodies, with 60% of the group in the age range of 1 to 3 years. Among 10 day-care centers analyzed, the prevalence of the biomarker IgM anti-HAV was 3.2%, with an uniform distribution of the cases in the group of children ranging in age from 1 to 4 years. Multi-variate analysis was performed to investigate the sociodemographic factors that could influence the results. It was verified that the risk for the infection increased with the length of the attendance in the day-care centers, i.e., the risk for children with attendance of one year or more was 4.7 times higher, when compared with children with one month attendance (CI 95% 2.3-9.9). According to the results, hepatitis A is an endemic infection in day-care centers in the study area. The length of attendance in the day-care settings was demonstrated to be a risk factor for the HAV infection. Such findings suggest that if hepatits A vaccination becomes available as a routine policy in our region, the target group should be children under one year. Moreover, those children should receive the vaccine before they start to attend the day-care centers. Um estudo soroepidemiológico para o vírus da hepatite A (VHA), investigando os marcadores de infecção passada (anti-VHA total - IgG e IgM) e infecção recente (anti-VHA IgM), foi realizado entre 1991 e 1992, em crianças de creche de Goiânia-Brasil central. Das 310 crianças com idade entre 03 meses e 09 anos, 69,7% mostraram soropositividade ao anti-VHA ... |
format |
Article in Journal/Newspaper |
author |
D.A.O. Queiróz D.D.P. Cardoso C.M.T. Martelli R.M.B. Martins S.O.B. Porto A.M.T. Borges M.S.P. Azevedo R.R. Daher |
author_facet |
D.A.O. Queiróz D.D.P. Cardoso C.M.T. Martelli R.M.B. Martins S.O.B. Porto A.M.T. Borges M.S.P. Azevedo R.R. Daher |
author_sort |
D.A.O. Queiróz |
title |
Risk factors and prevalence of antibodies against hepatitis A virus (HAV) in children from day-care centers, in Goiania, Brazil Fatores de risco e prevalência de anticorpos contra o vírus da hepatite A (VHA) em crianças de creche em Goiânia, Brasil |
title_short |
Risk factors and prevalence of antibodies against hepatitis A virus (HAV) in children from day-care centers, in Goiania, Brazil Fatores de risco e prevalência de anticorpos contra o vírus da hepatite A (VHA) em crianças de creche em Goiânia, Brasil |
title_full |
Risk factors and prevalence of antibodies against hepatitis A virus (HAV) in children from day-care centers, in Goiania, Brazil Fatores de risco e prevalência de anticorpos contra o vírus da hepatite A (VHA) em crianças de creche em Goiânia, Brasil |
title_fullStr |
Risk factors and prevalence of antibodies against hepatitis A virus (HAV) in children from day-care centers, in Goiania, Brazil Fatores de risco e prevalência de anticorpos contra o vírus da hepatite A (VHA) em crianças de creche em Goiânia, Brasil |
title_full_unstemmed |
Risk factors and prevalence of antibodies against hepatitis A virus (HAV) in children from day-care centers, in Goiania, Brazil Fatores de risco e prevalência de anticorpos contra o vírus da hepatite A (VHA) em crianças de creche em Goiânia, Brasil |
title_sort |
risk factors and prevalence of antibodies against hepatitis a virus (hav) in children from day-care centers, in goiania, brazil fatores de risco e prevalência de anticorpos contra o vírus da hepatite a (vha) em crianças de creche em goiânia, brasil |
publisher |
Universidade de São Paulo (USP) |
publishDate |
1995 |
url |
https://doi.org/10.1590/S0036-46651995000500008 https://doaj.org/article/dbafa76a2d5448c28d2181cdbcd3719a |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 37, Iss 5, Pp 427-433 (1995) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651995000500008 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651995000500008 0036-4665 1678-9946 https://doaj.org/article/dbafa76a2d5448c28d2181cdbcd3719a |
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https://doi.org/10.1590/S0036-46651995000500008 |
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