The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana
Background. Bloodstream infections are among the top causes of morbidity and mortality in people of all ages, especially in immunocompromised patients in sub-Saharan Africa. This study aimed at describing the epidemiology of bloodstream infections and antimicrobial susceptibility pattern over a nine...
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ftdoajarticles:oai:doaj.org/article:d9d8236d4ce14348a94bf3e185c519d1 2024-09-09T19:27:03+00:00 The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana John Gameli Deku Mavis Puopelle Dakorah Sylvester Yao Lokpo Verner N. Orish Francis Abeku Ussher Godsway Edem Kpene Vida Angmorkie Eshun Eunice Agyei Waldermer Attivor James Osei-Yeboah 2019-01-01T00:00:00Z https://doi.org/10.1155/2019/6750864 https://doaj.org/article/d9d8236d4ce14348a94bf3e185c519d1 EN eng Wiley http://dx.doi.org/10.1155/2019/6750864 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2019/6750864 https://doaj.org/article/d9d8236d4ce14348a94bf3e185c519d1 Journal of Tropical Medicine, Vol 2019 (2019) Arctic medicine. Tropical medicine RC955-962 article 2019 ftdoajarticles https://doi.org/10.1155/2019/6750864 2024-08-05T17:48:36Z Background. Bloodstream infections are among the top causes of morbidity and mortality in people of all ages, especially in immunocompromised patients in sub-Saharan Africa. This study aimed at describing the epidemiology of bloodstream infections and antimicrobial susceptibility pattern over a nine-year period at St. Dominic Hospital, Akwatia, in the Eastern Region of Ghana. Method. This study retrospectively analysed data from 4,489 patients who were referred to the Laboratory Department for blood culture and sensitivity testing from January 2009 to December 2017. Sociodemographic data included age, gender, and patients’ department. Blood culture results were retrieved from archival records in the laboratory. The authorities of St. Dominic Hospital granted approval for the study. Results. The incidence of bloodstream infection over the 9 years was 51.4 positive cultures per 100,000 hospital attendance. Staphylococcus aureus was the leading causative agent of bacteraemia for the first two scalar years (2009–2011 (38.9%) and 2012–2014 (42.2%)) while coagulase-negative staphylococcus (CoNS) (50.5%) was predominant for the last scalar year (2015–2017), followed by Staphylococcus aureus (169/587 (28.8%)). The highest incidence of bloodstream infections was recorded in the wet seasons (months of May (8.9 per 10,000 persons) and October (10.1 per 10,000 persons)). The bacterial isolates demonstrated high resistance to tetracyclines (390/531 (73.4%)), penicillins (1282/1669 (76.8%)), and sulphonamides (450/499 (90.2%)). Conclusion. Bloodstream infection and antimicrobial resistance are high in patients seeking healthcare in Akwatia. This therefore calls for concerted efforts aimed at reducing the incidence in the study area. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Tropical Medicine 2019 1 10 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 |
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Arctic medicine. Tropical medicine RC955-962 John Gameli Deku Mavis Puopelle Dakorah Sylvester Yao Lokpo Verner N. Orish Francis Abeku Ussher Godsway Edem Kpene Vida Angmorkie Eshun Eunice Agyei Waldermer Attivor James Osei-Yeboah The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
Background. Bloodstream infections are among the top causes of morbidity and mortality in people of all ages, especially in immunocompromised patients in sub-Saharan Africa. This study aimed at describing the epidemiology of bloodstream infections and antimicrobial susceptibility pattern over a nine-year period at St. Dominic Hospital, Akwatia, in the Eastern Region of Ghana. Method. This study retrospectively analysed data from 4,489 patients who were referred to the Laboratory Department for blood culture and sensitivity testing from January 2009 to December 2017. Sociodemographic data included age, gender, and patients’ department. Blood culture results were retrieved from archival records in the laboratory. The authorities of St. Dominic Hospital granted approval for the study. Results. The incidence of bloodstream infection over the 9 years was 51.4 positive cultures per 100,000 hospital attendance. Staphylococcus aureus was the leading causative agent of bacteraemia for the first two scalar years (2009–2011 (38.9%) and 2012–2014 (42.2%)) while coagulase-negative staphylococcus (CoNS) (50.5%) was predominant for the last scalar year (2015–2017), followed by Staphylococcus aureus (169/587 (28.8%)). The highest incidence of bloodstream infections was recorded in the wet seasons (months of May (8.9 per 10,000 persons) and October (10.1 per 10,000 persons)). The bacterial isolates demonstrated high resistance to tetracyclines (390/531 (73.4%)), penicillins (1282/1669 (76.8%)), and sulphonamides (450/499 (90.2%)). Conclusion. Bloodstream infection and antimicrobial resistance are high in patients seeking healthcare in Akwatia. This therefore calls for concerted efforts aimed at reducing the incidence in the study area. |
format |
Article in Journal/Newspaper |
author |
John Gameli Deku Mavis Puopelle Dakorah Sylvester Yao Lokpo Verner N. Orish Francis Abeku Ussher Godsway Edem Kpene Vida Angmorkie Eshun Eunice Agyei Waldermer Attivor James Osei-Yeboah |
author_facet |
John Gameli Deku Mavis Puopelle Dakorah Sylvester Yao Lokpo Verner N. Orish Francis Abeku Ussher Godsway Edem Kpene Vida Angmorkie Eshun Eunice Agyei Waldermer Attivor James Osei-Yeboah |
author_sort |
John Gameli Deku |
title |
The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana |
title_short |
The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana |
title_full |
The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana |
title_fullStr |
The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana |
title_full_unstemmed |
The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana |
title_sort |
epidemiology of bloodstream infections and antimicrobial susceptibility patterns: a nine-year retrospective study at st. dominic hospital, akwatia, ghana |
publisher |
Wiley |
publishDate |
2019 |
url |
https://doi.org/10.1155/2019/6750864 https://doaj.org/article/d9d8236d4ce14348a94bf3e185c519d1 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2019 (2019) |
op_relation |
http://dx.doi.org/10.1155/2019/6750864 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2019/6750864 https://doaj.org/article/d9d8236d4ce14348a94bf3e185c519d1 |
op_doi |
https://doi.org/10.1155/2019/6750864 |
container_title |
Journal of Tropical Medicine |
container_volume |
2019 |
container_start_page |
1 |
op_container_end_page |
10 |
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1809896555287674880 |