Frequency of anti- Toxoplasma gondii IgA, IgM, and IgG antibodies in high-risk pregnancies, in Brazil

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Fernando Henrique Antunes Murata, Marina Neves Ferreira, Natália Sahyoun Camargo, Gabriela Soria Santos, Lígia Cosentino Junqueira Franco Spegiorin, Aparecida Perpétuo Silveira-Carvalho, Vera Lucia Pereira-Chioccola, Luiz Carlos de Mattos, Cinara Cássia Brandão de Mattos
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT)
• Subjects: Toxoplasma gondii; Acute infection; High-risk pregnancy; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/0037-8682-0046-2016; https://doaj.org/article/d9229bce18bc43fbb4ac3d5421b8dc5e

Abstract: INTRODUCTION Toxoplasmosis during pregnancy can be severe; thus, it is essential to diagnose the disease via serological tests. METHODS An enzyme-linked immunosorbent assay (ELISA) was used to investigate anti-Toxoplasma gondii immunoglobulin A (IgA), M (IgM) and G (IgG) antibodies in 62 high-risk pregnant women. RESULTS Forty-three (69.4%) women were positive for IgA, 31 (50%) for IgG, and 57 (91.9%) for IgM; 4 (6,5%) were positive for IgA but negative for IgM; 10 (16.1%) were negative for IgA and IgM but positive for IgG. CONCLUSIONS Testing for these antibodies can help diagnose infection in pregnant women, thereby contributing to clinical management.