Hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of Candida albicans isolated from recurrent urinary tract infections
Objective: To explore the prevention of recurrent candiduria using natural based approaches and to study the antimicrobial effect of Hibiscus sabdariffa (H. sabdariffa) extract and the biofilm forming capacity of Candida albicans strains in the present of the H. sabdariffa extract. Methods: In this...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2014
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Online Access: | https://doi.org/10.1016/S2221-1691(14)60217-3 https://doaj.org/article/d8ac266a2e454ad1a5fb05ffcde63713 |
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ftdoajarticles:oai:doaj.org/article:d8ac266a2e454ad1a5fb05ffcde63713 2023-05-15T15:06:30+02:00 Hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of Candida albicans isolated from recurrent urinary tract infections Issam Alshami Ahmed E Alharbi 2014-02-01T00:00:00Z https://doi.org/10.1016/S2221-1691(14)60217-3 https://doaj.org/article/d8ac266a2e454ad1a5fb05ffcde63713 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115301787 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(14)60217-3 https://doaj.org/article/d8ac266a2e454ad1a5fb05ffcde63713 Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 2, Pp 104-108 (2014) Hibiscus sabdariffa Biofilm Candiduria Candida albicans UTIs Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2014 ftdoajarticles https://doi.org/10.1016/S2221-1691(14)60217-3 2022-12-31T07:25:10Z Objective: To explore the prevention of recurrent candiduria using natural based approaches and to study the antimicrobial effect of Hibiscus sabdariffa (H. sabdariffa) extract and the biofilm forming capacity of Candida albicans strains in the present of the H. sabdariffa extract. Methods: In this particular study, six strains of fluconazole resistant Candida albicans isolated from recurrent candiduria were used. The susceptibility of fungal isolates, time-kill curves and biofilm forming capacity in the present of the H. sabdariffa extract were determined. Results: Various levels minimum inhibitory concentration of the extract were observed against all the isolates. Minimum inhibitory concentration values ranged from 0.5 to 2.0 mg/mL. Time-kill experiment demonstrated that the effect was fungistatic. The biofilm inhibition assay results showed that H. sabdariffa extract inhibited biofilm production of all the isolates. Conclusions: The results of the study support the potential effect of H. sabdariffa extract for preventing recurrent candiduria and emphasize the significance of the plant extract approach as a potential antifungal agent. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 4 2 104 108 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Hibiscus sabdariffa Biofilm Candiduria Candida albicans UTIs Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
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Hibiscus sabdariffa Biofilm Candiduria Candida albicans UTIs Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Issam Alshami Ahmed E Alharbi Hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of Candida albicans isolated from recurrent urinary tract infections |
topic_facet |
Hibiscus sabdariffa Biofilm Candiduria Candida albicans UTIs Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To explore the prevention of recurrent candiduria using natural based approaches and to study the antimicrobial effect of Hibiscus sabdariffa (H. sabdariffa) extract and the biofilm forming capacity of Candida albicans strains in the present of the H. sabdariffa extract. Methods: In this particular study, six strains of fluconazole resistant Candida albicans isolated from recurrent candiduria were used. The susceptibility of fungal isolates, time-kill curves and biofilm forming capacity in the present of the H. sabdariffa extract were determined. Results: Various levels minimum inhibitory concentration of the extract were observed against all the isolates. Minimum inhibitory concentration values ranged from 0.5 to 2.0 mg/mL. Time-kill experiment demonstrated that the effect was fungistatic. The biofilm inhibition assay results showed that H. sabdariffa extract inhibited biofilm production of all the isolates. Conclusions: The results of the study support the potential effect of H. sabdariffa extract for preventing recurrent candiduria and emphasize the significance of the plant extract approach as a potential antifungal agent. |
format |
Article in Journal/Newspaper |
author |
Issam Alshami Ahmed E Alharbi |
author_facet |
Issam Alshami Ahmed E Alharbi |
author_sort |
Issam Alshami |
title |
Hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of Candida albicans isolated from recurrent urinary tract infections |
title_short |
Hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of Candida albicans isolated from recurrent urinary tract infections |
title_full |
Hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of Candida albicans isolated from recurrent urinary tract infections |
title_fullStr |
Hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of Candida albicans isolated from recurrent urinary tract infections |
title_full_unstemmed |
Hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of Candida albicans isolated from recurrent urinary tract infections |
title_sort |
hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of candida albicans isolated from recurrent urinary tract infections |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2014 |
url |
https://doi.org/10.1016/S2221-1691(14)60217-3 https://doaj.org/article/d8ac266a2e454ad1a5fb05ffcde63713 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 2, Pp 104-108 (2014) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115301787 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(14)60217-3 https://doaj.org/article/d8ac266a2e454ad1a5fb05ffcde63713 |
op_doi |
https://doi.org/10.1016/S2221-1691(14)60217-3 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
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4 |
container_issue |
2 |
container_start_page |
104 |
op_container_end_page |
108 |
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1766338098899189760 |