An encapsulated Yersinia pseudotuberculosis is a highly efficient vaccine against pneumonic plague.

• Published in: PLoS Neglected Tropical Diseases
• Main Authors: Anne Derbise, Alba Cerdà Marín, Patrick Ave, Thierry Blisnick, Michel Huerre, Elisabeth Carniel, Christian E Demeure
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2012
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; The ''Y''
• Online Access: https://doi.org/10.1371/journal.pntd.0001528; https://doaj.org/article/d8a89df11740421b8de38dc3f5a68da0

BACKGROUND: Plague is still a public health problem in the world and is re-emerging, but no efficient vaccine is available. We previously reported that oral inoculation of a live attenuated Yersinia pseudotuberculosis, the recent ancestor of Yersinia pestis, provided protection against bubonic plagu...