Lipoprotein profile in girls with asymptomatic hyperuricemia
To investigate the relation between uricemia and lipid profile, 539 Arkhangelsk schoolgirls aged 7-17 were examined. With upper norm limit of 0. 31 mmol/l, the prevalence of asymptomatic chronic hyperuricemia among Arkhangelsk girls was as high as 25 %. With uricemia higher than 0. 31 mmol/l, total...
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2004
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ftdoajarticles:oai:doaj.org/article:d7f50a5691af451087f87fa5d19f9cb9 2023-05-15T15:23:39+02:00 Lipoprotein profile in girls with asymptomatic hyperuricemia S. I. Maljavskaya T. A. Toropygina V. E. Tril V. A. Ternovskaya 2004-02-01T00:00:00Z https://doaj.org/article/d7f50a5691af451087f87fa5d19f9cb9 RU rus «FIRMA «SILICEA» LLC https://russjcardiol.elpub.ru/jour/article/view/1857 https://doaj.org/toc/1560-4071 https://doaj.org/toc/2618-7620 1560-4071 2618-7620 https://doaj.org/article/d7f50a5691af451087f87fa5d19f9cb9 Российский кардиологический журнал, Vol 0, Iss 1, Pp 33-37 (2004) chronic asymptomatic hyperuricemia liporotein profile atherogenic phenotype atherosclerosis prevention adolescence Diseases of the circulatory (Cardiovascular) system RC666-701 article 2004 ftdoajarticles 2022-12-30T23:40:19Z To investigate the relation between uricemia and lipid profile, 539 Arkhangelsk schoolgirls aged 7-17 were examined. With upper norm limit of 0. 31 mmol/l, the prevalence of asymptomatic chronic hyperuricemia among Arkhangelsk girls was as high as 25 %. With uricemia higher than 0. 31 mmol/l, total cholesterol, triglycerides, LDL cholesterol levels were significantly elevated. Mean total cholesterol levels in such individuals were higher than WHO norms of normocholesterolemia for children and adolescents. From the other hand, among individuals with dyslipidemia, uricemia more than 0. 31 mmol/l was diagnosed significantly more frequently. All measured lipid and liporotein parameters directly correlated with uricemia level, and inversely correlated with urate excretion rate, regardless of pathogenetic hyperuricemia mechanisms. Our results point to the fact that chronic hyperuricemia is assosiated with atherogenic lipid/lipoprotein phenotype, observed as early as in childhood, and possibly acts as an indicator of atherosclerosis risk. Therefore, use of a lower norm for population screening seems rational, from position of primary and secondary prevention of atherosclerosis. Our data support detailed examination of lipid metabolism if uricemia is higher than 0. 31 mmol/l. Article in Journal/Newspaper Arkhangelsk Directory of Open Access Journals: DOAJ Articles |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
Russian |
topic |
chronic asymptomatic hyperuricemia liporotein profile atherogenic phenotype atherosclerosis prevention adolescence Diseases of the circulatory (Cardiovascular) system RC666-701 |
spellingShingle |
chronic asymptomatic hyperuricemia liporotein profile atherogenic phenotype atherosclerosis prevention adolescence Diseases of the circulatory (Cardiovascular) system RC666-701 S. I. Maljavskaya T. A. Toropygina V. E. Tril V. A. Ternovskaya Lipoprotein profile in girls with asymptomatic hyperuricemia |
topic_facet |
chronic asymptomatic hyperuricemia liporotein profile atherogenic phenotype atherosclerosis prevention adolescence Diseases of the circulatory (Cardiovascular) system RC666-701 |
description |
To investigate the relation between uricemia and lipid profile, 539 Arkhangelsk schoolgirls aged 7-17 were examined. With upper norm limit of 0. 31 mmol/l, the prevalence of asymptomatic chronic hyperuricemia among Arkhangelsk girls was as high as 25 %. With uricemia higher than 0. 31 mmol/l, total cholesterol, triglycerides, LDL cholesterol levels were significantly elevated. Mean total cholesterol levels in such individuals were higher than WHO norms of normocholesterolemia for children and adolescents. From the other hand, among individuals with dyslipidemia, uricemia more than 0. 31 mmol/l was diagnosed significantly more frequently. All measured lipid and liporotein parameters directly correlated with uricemia level, and inversely correlated with urate excretion rate, regardless of pathogenetic hyperuricemia mechanisms. Our results point to the fact that chronic hyperuricemia is assosiated with atherogenic lipid/lipoprotein phenotype, observed as early as in childhood, and possibly acts as an indicator of atherosclerosis risk. Therefore, use of a lower norm for population screening seems rational, from position of primary and secondary prevention of atherosclerosis. Our data support detailed examination of lipid metabolism if uricemia is higher than 0. 31 mmol/l. |
format |
Article in Journal/Newspaper |
author |
S. I. Maljavskaya T. A. Toropygina V. E. Tril V. A. Ternovskaya |
author_facet |
S. I. Maljavskaya T. A. Toropygina V. E. Tril V. A. Ternovskaya |
author_sort |
S. I. Maljavskaya |
title |
Lipoprotein profile in girls with asymptomatic hyperuricemia |
title_short |
Lipoprotein profile in girls with asymptomatic hyperuricemia |
title_full |
Lipoprotein profile in girls with asymptomatic hyperuricemia |
title_fullStr |
Lipoprotein profile in girls with asymptomatic hyperuricemia |
title_full_unstemmed |
Lipoprotein profile in girls with asymptomatic hyperuricemia |
title_sort |
lipoprotein profile in girls with asymptomatic hyperuricemia |
publisher |
«FIRMA «SILICEA» LLC |
publishDate |
2004 |
url |
https://doaj.org/article/d7f50a5691af451087f87fa5d19f9cb9 |
genre |
Arkhangelsk |
genre_facet |
Arkhangelsk |
op_source |
Российский кардиологический журнал, Vol 0, Iss 1, Pp 33-37 (2004) |
op_relation |
https://russjcardiol.elpub.ru/jour/article/view/1857 https://doaj.org/toc/1560-4071 https://doaj.org/toc/2618-7620 1560-4071 2618-7620 https://doaj.org/article/d7f50a5691af451087f87fa5d19f9cb9 |
_version_ |
1766354305594425344 |