Long term outcomes and prognostics of visceral leishmaniasis in HIV infected patients with use of pentamidine as secondary prophylaxis based on CD4 level: a prospective cohort study in Ethiopia.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Ermias Diro, Tansy Edwards, Koert Ritmeijer, Helina Fikre, Charles Abongomera, Aderajew Kibret, Clélia Bardonneau, Peninah Soipei, Brian Mutinda, Raymond Omollo, Johan van Griensven, Eduard E Zijlstra, Monique Wasunna, Fabiana Alves, Jorge Alvar, Asrat Hailu, Neal Alexander, Séverine Blesson
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2019
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Meier
• Online Access: https://doi.org/10.1371/journal.pntd.0007132; https://doaj.org/article/d7d41278dcee4a21a819af1de360a1f6

BACKGROUND:The long-term treatment outcome of visceral leishmaniasis (VL) patients with HIV co-infection is complicated by a high rate of relapse, especially when the CD4 count is low. Although use of secondary prophylaxis is recommended, it is not routinely practiced and data on its effectiveness a...