Changing patterns of malaria during 1996-2010 in an area of moderate transmission in Southern Senegal
Abstract Background Malaria is reportedly receding in different epidemiological settings, but local long-term surveys are limited. At Mlomp dispensary in south-western Senegal, an area of moderate malaria transmission, year-round, clinically-suspected malaria was treated with monotherapy as per WHO...
Published in: | Malaria Journal |
---|---|
Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2011
|
Subjects: | |
Online Access: | https://doi.org/10.1186/1475-2875-10-203 https://doaj.org/article/d6e2e63e2f384d858d7e9d66ac043362 |
id |
ftdoajarticles:oai:doaj.org/article:d6e2e63e2f384d858d7e9d66ac043362 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:d6e2e63e2f384d858d7e9d66ac043362 2023-05-15T15:09:53+02:00 Changing patterns of malaria during 1996-2010 in an area of moderate transmission in Southern Senegal Vaillant Michel T Agnamey Patrice Badiane Malick Cisse Moustafa Brasseur Philippe Olliaro Piero L 2011-07-01T00:00:00Z https://doi.org/10.1186/1475-2875-10-203 https://doaj.org/article/d6e2e63e2f384d858d7e9d66ac043362 EN eng BMC http://www.malariajournal.com/content/10/1/203 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-10-203 1475-2875 https://doaj.org/article/d6e2e63e2f384d858d7e9d66ac043362 Malaria Journal, Vol 10, Iss 1, p 203 (2011) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2011 ftdoajarticles https://doi.org/10.1186/1475-2875-10-203 2022-12-30T22:35:16Z Abstract Background Malaria is reportedly receding in different epidemiological settings, but local long-term surveys are limited. At Mlomp dispensary in south-western Senegal, an area of moderate malaria transmission, year-round, clinically-suspected malaria was treated with monotherapy as per WHO and national policy in the 1990s. Since 2000, there has been a staggered deployment of artesunate-amodiaquine after parasitological confirmation; this was adopted nationally in 2006. Methods Data were extracted from clinic registers for the period between January 1996 and December 2010, analysed and modelled. Results Over the 15-year study period, the risk of malaria decreased about 32-times (from 0.4 to 0.012 episodes person-year), while anti-malarial treatments decreased 13-times (from 0.9 to 0.07 treatments person-year) and consultations for fever decreased 3-times (from 1.8 to 0.6 visits person-year). This was paralleled by changes in the age profile of malaria patients so that the risk of malaria is now almost uniformly distributed throughout life, while in the past malaria used to concern more children below 16 years of age. Conclusions This study provides direct evidence of malaria risk receding between 1996-2010 and becoming equal throughout life where transmission used to be moderate. Infection rates are no longer enough to sustain immunity. Temporally, this coincides with deploying artemisinin combinations on parasitological confirmation, but other contributing causes are unclear. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 10 1 203 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Vaillant Michel T Agnamey Patrice Badiane Malick Cisse Moustafa Brasseur Philippe Olliaro Piero L Changing patterns of malaria during 1996-2010 in an area of moderate transmission in Southern Senegal |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Malaria is reportedly receding in different epidemiological settings, but local long-term surveys are limited. At Mlomp dispensary in south-western Senegal, an area of moderate malaria transmission, year-round, clinically-suspected malaria was treated with monotherapy as per WHO and national policy in the 1990s. Since 2000, there has been a staggered deployment of artesunate-amodiaquine after parasitological confirmation; this was adopted nationally in 2006. Methods Data were extracted from clinic registers for the period between January 1996 and December 2010, analysed and modelled. Results Over the 15-year study period, the risk of malaria decreased about 32-times (from 0.4 to 0.012 episodes person-year), while anti-malarial treatments decreased 13-times (from 0.9 to 0.07 treatments person-year) and consultations for fever decreased 3-times (from 1.8 to 0.6 visits person-year). This was paralleled by changes in the age profile of malaria patients so that the risk of malaria is now almost uniformly distributed throughout life, while in the past malaria used to concern more children below 16 years of age. Conclusions This study provides direct evidence of malaria risk receding between 1996-2010 and becoming equal throughout life where transmission used to be moderate. Infection rates are no longer enough to sustain immunity. Temporally, this coincides with deploying artemisinin combinations on parasitological confirmation, but other contributing causes are unclear. |
format |
Article in Journal/Newspaper |
author |
Vaillant Michel T Agnamey Patrice Badiane Malick Cisse Moustafa Brasseur Philippe Olliaro Piero L |
author_facet |
Vaillant Michel T Agnamey Patrice Badiane Malick Cisse Moustafa Brasseur Philippe Olliaro Piero L |
author_sort |
Vaillant Michel T |
title |
Changing patterns of malaria during 1996-2010 in an area of moderate transmission in Southern Senegal |
title_short |
Changing patterns of malaria during 1996-2010 in an area of moderate transmission in Southern Senegal |
title_full |
Changing patterns of malaria during 1996-2010 in an area of moderate transmission in Southern Senegal |
title_fullStr |
Changing patterns of malaria during 1996-2010 in an area of moderate transmission in Southern Senegal |
title_full_unstemmed |
Changing patterns of malaria during 1996-2010 in an area of moderate transmission in Southern Senegal |
title_sort |
changing patterns of malaria during 1996-2010 in an area of moderate transmission in southern senegal |
publisher |
BMC |
publishDate |
2011 |
url |
https://doi.org/10.1186/1475-2875-10-203 https://doaj.org/article/d6e2e63e2f384d858d7e9d66ac043362 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 10, Iss 1, p 203 (2011) |
op_relation |
http://www.malariajournal.com/content/10/1/203 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-10-203 1475-2875 https://doaj.org/article/d6e2e63e2f384d858d7e9d66ac043362 |
op_doi |
https://doi.org/10.1186/1475-2875-10-203 |
container_title |
Malaria Journal |
container_volume |
10 |
container_issue |
1 |
container_start_page |
203 |
_version_ |
1766340988935077888 |