Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements
Antibiotic resistance genes (ARGs) are undergoing a remarkably rapid geographic expansion in various ecosystems, including pristine environments such as Antarctica. The study of ARGs and environmental resistance genes (ERGs) mechanisms could provide a better understanding of their origin, evolution,...
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2022
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ftdoajarticles:oai:doaj.org/article:d549c2f0fb2c4767b7c7e4b68c163f97 2023-05-15T13:44:41+02:00 Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements Andrés Santos Felipe Burgos Jaime Martinez-Urtaza Leticia Barrientos 2022-07-01T00:00:00Z https://doi.org/10.3390/microorganisms10071432 https://doaj.org/article/d549c2f0fb2c4767b7c7e4b68c163f97 EN eng MDPI AG https://www.mdpi.com/2076-2607/10/7/1432 https://doaj.org/toc/2076-2607 doi:10.3390/microorganisms10071432 2076-2607 https://doaj.org/article/d549c2f0fb2c4767b7c7e4b68c163f97 Microorganisms, Vol 10, Iss 1432, p 1432 (2022) Antarctic soils phages plasmids pristine environments Biology (General) QH301-705.5 article 2022 ftdoajarticles https://doi.org/10.3390/microorganisms10071432 2022-12-31T01:04:07Z Antibiotic resistance genes (ARGs) are undergoing a remarkably rapid geographic expansion in various ecosystems, including pristine environments such as Antarctica. The study of ARGs and environmental resistance genes (ERGs) mechanisms could provide a better understanding of their origin, evolution, and dissemination in these pristine environments. Here, we describe the diversity of ARGs and ERGs and the importance of mobile genetic elements as a possible mechanism for the dissemination of resistance genes in Antarctica. We analyzed five soil metagenomes from Deception Island in Antarctica. Results showed that detected ARGs are associated with mechanisms such as antibiotic efflux, antibiotic inactivation, and target alteration. On the other hand, resistance to metals, surfactants, and aromatic hydrocarbons were the dominant ERGs. The taxonomy of ARGs showed that Pseudomonas , Psychrobacter , and Staphylococcus could be key taxa for studying antibiotic resistance and environmental resistance to stress in Deception Island. In addition, results showed that ARGs are mainly associated with phage-type mobile elements suggesting a potential role in their dissemination and prevalence. Finally, these results provide valuable information regarding the ARGs and ERGs in Deception Island including the potential contribution of mobile genetic elements to the spread of ARGs and ERGs in one of the least studied Antarctic ecosystems to date. Article in Journal/Newspaper Antarc* Antarctic Antarctica Deception Island Directory of Open Access Journals: DOAJ Articles Antarctic Deception Island ENVELOPE(-60.633,-60.633,-62.950,-62.950) Microorganisms 10 7 1432 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Antarctic soils phages plasmids pristine environments Biology (General) QH301-705.5 |
spellingShingle |
Antarctic soils phages plasmids pristine environments Biology (General) QH301-705.5 Andrés Santos Felipe Burgos Jaime Martinez-Urtaza Leticia Barrientos Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
topic_facet |
Antarctic soils phages plasmids pristine environments Biology (General) QH301-705.5 |
description |
Antibiotic resistance genes (ARGs) are undergoing a remarkably rapid geographic expansion in various ecosystems, including pristine environments such as Antarctica. The study of ARGs and environmental resistance genes (ERGs) mechanisms could provide a better understanding of their origin, evolution, and dissemination in these pristine environments. Here, we describe the diversity of ARGs and ERGs and the importance of mobile genetic elements as a possible mechanism for the dissemination of resistance genes in Antarctica. We analyzed five soil metagenomes from Deception Island in Antarctica. Results showed that detected ARGs are associated with mechanisms such as antibiotic efflux, antibiotic inactivation, and target alteration. On the other hand, resistance to metals, surfactants, and aromatic hydrocarbons were the dominant ERGs. The taxonomy of ARGs showed that Pseudomonas , Psychrobacter , and Staphylococcus could be key taxa for studying antibiotic resistance and environmental resistance to stress in Deception Island. In addition, results showed that ARGs are mainly associated with phage-type mobile elements suggesting a potential role in their dissemination and prevalence. Finally, these results provide valuable information regarding the ARGs and ERGs in Deception Island including the potential contribution of mobile genetic elements to the spread of ARGs and ERGs in one of the least studied Antarctic ecosystems to date. |
format |
Article in Journal/Newspaper |
author |
Andrés Santos Felipe Burgos Jaime Martinez-Urtaza Leticia Barrientos |
author_facet |
Andrés Santos Felipe Burgos Jaime Martinez-Urtaza Leticia Barrientos |
author_sort |
Andrés Santos |
title |
Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
title_short |
Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
title_full |
Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
title_fullStr |
Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
title_full_unstemmed |
Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements |
title_sort |
metagenomic characterization of resistance genes in deception island and their association with mobile genetic elements |
publisher |
MDPI AG |
publishDate |
2022 |
url |
https://doi.org/10.3390/microorganisms10071432 https://doaj.org/article/d549c2f0fb2c4767b7c7e4b68c163f97 |
long_lat |
ENVELOPE(-60.633,-60.633,-62.950,-62.950) |
geographic |
Antarctic Deception Island |
geographic_facet |
Antarctic Deception Island |
genre |
Antarc* Antarctic Antarctica Deception Island |
genre_facet |
Antarc* Antarctic Antarctica Deception Island |
op_source |
Microorganisms, Vol 10, Iss 1432, p 1432 (2022) |
op_relation |
https://www.mdpi.com/2076-2607/10/7/1432 https://doaj.org/toc/2076-2607 doi:10.3390/microorganisms10071432 2076-2607 https://doaj.org/article/d549c2f0fb2c4767b7c7e4b68c163f97 |
op_doi |
https://doi.org/10.3390/microorganisms10071432 |
container_title |
Microorganisms |
container_volume |
10 |
container_issue |
7 |
container_start_page |
1432 |
_version_ |
1766204848711139328 |