Pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis.
Importance Trichiasis surgery programs globally have faced high rates of poor surgical outcomes. Identifying correctable risk factors for improving long-term outcomes is essential for countries targeting elimination of trachoma as a public health problem. Objective To determine whether the location...
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ftdoajarticles:oai:doaj.org/article:d5217fdcb40d4c6a9fc277244a7fded1 2023-05-15T15:16:15+02:00 Pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis. Emily W Gower Beatriz Munoz Saul Rajak Esmael Habtamu Sheila K West Shannath L Merbs Jennifer C Harding Wondu Alemayehu E Kelly Callahan Paul M Emerson Teshome Gebre Matthew J Burton 2019-10-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0007637 https://doaj.org/article/d5217fdcb40d4c6a9fc277244a7fded1 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0007637 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007637 https://doaj.org/article/d5217fdcb40d4c6a9fc277244a7fded1 PLoS Neglected Tropical Diseases, Vol 13, Iss 10, p e0007637 (2019) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2019 ftdoajarticles https://doi.org/10.1371/journal.pntd.0007637 2022-12-31T07:16:57Z Importance Trichiasis surgery programs globally have faced high rates of poor surgical outcomes. Identifying correctable risk factors for improving long-term outcomes is essential for countries targeting elimination of trachoma as a public health problem. Objective To determine whether the location of trichiatic eyelashes prior to surgery influences development of post-operative trichiasis (PTT) within two years after surgery. Design Secondary data analysis of four randomized clinical trials evaluating methods to improve trichiasis surgery outcomes. These include the Surgery for Trichiasis, Antibiotics for Recurrence (STAR) trial, Partnership for Rapid Elimination of Trachoma (PRET-Surgery), absorbable versus silk sutures trial, and epilation versus surgery for minor trichiasis trial. Setting Primary trials were conducted in rural areas of Ethiopia and Tanzania. Interventions or exposures Trichiasis surgery performed with either the bilamellar tarsal rotation procedure or posterior lamellar rotation procedure. Main outcomes Prevalence of PTT within two years after surgery, location of trichiatic eyelashes pre-operatively and post-operatively. Results 6,747 eyelids that underwent first-time trichiasis surgery were included. PTT rates varied by study, ranging from 10-40%. PTT was less severe (based on number of trichiatic eyelashes) than initial trichiasis for 72% of those developing PTT, and only 2% of eyelids were worse at follow up than pre-operatively. Eyelids with central only-trichiasis pre-operatively had lower rates of PTT than eyelids with peripheral only trichiasis in each of the three trials that included severe TT cases. 10% of eyelids with peripheral trichiasis pre-operatively that develop PTT have central TT post-operatively. Conclusions and relevance Pre-operative central trichiasis is less likely than peripheral trichiasis to be associated with subsequent PTT. Regardless of type of surgery, surgeon skill levels, or pre-operative trichiasis severity, the presence of peripheral trichiasis ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 13 10 e0007637 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Emily W Gower Beatriz Munoz Saul Rajak Esmael Habtamu Sheila K West Shannath L Merbs Jennifer C Harding Wondu Alemayehu E Kelly Callahan Paul M Emerson Teshome Gebre Matthew J Burton Pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Importance Trichiasis surgery programs globally have faced high rates of poor surgical outcomes. Identifying correctable risk factors for improving long-term outcomes is essential for countries targeting elimination of trachoma as a public health problem. Objective To determine whether the location of trichiatic eyelashes prior to surgery influences development of post-operative trichiasis (PTT) within two years after surgery. Design Secondary data analysis of four randomized clinical trials evaluating methods to improve trichiasis surgery outcomes. These include the Surgery for Trichiasis, Antibiotics for Recurrence (STAR) trial, Partnership for Rapid Elimination of Trachoma (PRET-Surgery), absorbable versus silk sutures trial, and epilation versus surgery for minor trichiasis trial. Setting Primary trials were conducted in rural areas of Ethiopia and Tanzania. Interventions or exposures Trichiasis surgery performed with either the bilamellar tarsal rotation procedure or posterior lamellar rotation procedure. Main outcomes Prevalence of PTT within two years after surgery, location of trichiatic eyelashes pre-operatively and post-operatively. Results 6,747 eyelids that underwent first-time trichiasis surgery were included. PTT rates varied by study, ranging from 10-40%. PTT was less severe (based on number of trichiatic eyelashes) than initial trichiasis for 72% of those developing PTT, and only 2% of eyelids were worse at follow up than pre-operatively. Eyelids with central only-trichiasis pre-operatively had lower rates of PTT than eyelids with peripheral only trichiasis in each of the three trials that included severe TT cases. 10% of eyelids with peripheral trichiasis pre-operatively that develop PTT have central TT post-operatively. Conclusions and relevance Pre-operative central trichiasis is less likely than peripheral trichiasis to be associated with subsequent PTT. Regardless of type of surgery, surgeon skill levels, or pre-operative trichiasis severity, the presence of peripheral trichiasis ... |
format |
Article in Journal/Newspaper |
author |
Emily W Gower Beatriz Munoz Saul Rajak Esmael Habtamu Sheila K West Shannath L Merbs Jennifer C Harding Wondu Alemayehu E Kelly Callahan Paul M Emerson Teshome Gebre Matthew J Burton |
author_facet |
Emily W Gower Beatriz Munoz Saul Rajak Esmael Habtamu Sheila K West Shannath L Merbs Jennifer C Harding Wondu Alemayehu E Kelly Callahan Paul M Emerson Teshome Gebre Matthew J Burton |
author_sort |
Emily W Gower |
title |
Pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis. |
title_short |
Pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis. |
title_full |
Pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis. |
title_fullStr |
Pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis. |
title_full_unstemmed |
Pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis. |
title_sort |
pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2019 |
url |
https://doi.org/10.1371/journal.pntd.0007637 https://doaj.org/article/d5217fdcb40d4c6a9fc277244a7fded1 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 13, Iss 10, p e0007637 (2019) |
op_relation |
https://doi.org/10.1371/journal.pntd.0007637 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007637 https://doaj.org/article/d5217fdcb40d4c6a9fc277244a7fded1 |
op_doi |
https://doi.org/10.1371/journal.pntd.0007637 |
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PLOS Neglected Tropical Diseases |
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13 |
container_issue |
10 |
container_start_page |
e0007637 |
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