Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector Anopheles stephensi : a case study in Mangalore city, South India
Abstract Background Synthetic pyrethroids are potent insecticides most commonly used in the vector control programme. These are applied for indoor residual sprays, space sprays and in impregnated bed nets. Resistance reduces the efficacy of insecticides. Thus, the susceptibility status of the target...
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ftdoajarticles:oai:doaj.org/article:d4c4016f64b84927b83f3fa5668518d8 2023-05-15T15:08:46+02:00 Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector Anopheles stephensi : a case study in Mangalore city, South India Dash Aditya P Ojha Vijay P Ghosh Susanta K Tiwari Satyanarayan Raghavendra Kamaraju 2010-06-01T00:00:00Z https://doi.org/10.1186/1475-2875-9-179 https://doaj.org/article/d4c4016f64b84927b83f3fa5668518d8 EN eng BMC http://www.malariajournal.com/content/9/1/179 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-179 1475-2875 https://doaj.org/article/d4c4016f64b84927b83f3fa5668518d8 Malaria Journal, Vol 9, Iss 1, p 179 (2010) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2010 ftdoajarticles https://doi.org/10.1186/1475-2875-9-179 2022-12-31T08:11:11Z Abstract Background Synthetic pyrethroids are potent insecticides most commonly used in the vector control programme. These are applied for indoor residual sprays, space sprays and in impregnated bed nets. Resistance reduces the efficacy of insecticides. Thus, the susceptibility status of the target vector(s) is monitored routinely to select the effective ones. A study was undertaken in a malaria endemic coastal city Mangalore, Karnataka, South India, against the known malaria vector Anopheles stephensi . Methods The susceptibility status was assessed at diagnostic doses of DDT (4%), malathion (5%), deltamethrin (0.05%), cyfluthrin (0.15%), alphacypermethrin (0.10%), lambdacyhalothrin (0.05%) and permethrin (0.75%) using the standard WHO tube test method during October/November 2006. Results Anopheles stephensi was resistant to malathion by 54.9%, but tolerant to deltamethrin by 86.1%, cyfluthrin 95.5% and alphacypermethrin 90.6%, whereas it was susceptible to DDT by 98.1%, lambdacyhalothrin 98.6% and permethrin 100.0%, respectively. The KDT 50 and KDT 95 values for these insecticides also showed the similar responses. Conclusion Susceptibility of An. stephensi to DDT is an important finding as this has never been used in Mangalore city, whereas its rural counterpart Anopheles culicifacies is widely resistant to this insecticide. The study explores the selection and rotation of the appropriate insecticide molecule even within the same group for effective vector management. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 9 1 179 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Dash Aditya P Ojha Vijay P Ghosh Susanta K Tiwari Satyanarayan Raghavendra Kamaraju Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector Anopheles stephensi : a case study in Mangalore city, South India |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Synthetic pyrethroids are potent insecticides most commonly used in the vector control programme. These are applied for indoor residual sprays, space sprays and in impregnated bed nets. Resistance reduces the efficacy of insecticides. Thus, the susceptibility status of the target vector(s) is monitored routinely to select the effective ones. A study was undertaken in a malaria endemic coastal city Mangalore, Karnataka, South India, against the known malaria vector Anopheles stephensi . Methods The susceptibility status was assessed at diagnostic doses of DDT (4%), malathion (5%), deltamethrin (0.05%), cyfluthrin (0.15%), alphacypermethrin (0.10%), lambdacyhalothrin (0.05%) and permethrin (0.75%) using the standard WHO tube test method during October/November 2006. Results Anopheles stephensi was resistant to malathion by 54.9%, but tolerant to deltamethrin by 86.1%, cyfluthrin 95.5% and alphacypermethrin 90.6%, whereas it was susceptible to DDT by 98.1%, lambdacyhalothrin 98.6% and permethrin 100.0%, respectively. The KDT 50 and KDT 95 values for these insecticides also showed the similar responses. Conclusion Susceptibility of An. stephensi to DDT is an important finding as this has never been used in Mangalore city, whereas its rural counterpart Anopheles culicifacies is widely resistant to this insecticide. The study explores the selection and rotation of the appropriate insecticide molecule even within the same group for effective vector management. |
format |
Article in Journal/Newspaper |
author |
Dash Aditya P Ojha Vijay P Ghosh Susanta K Tiwari Satyanarayan Raghavendra Kamaraju |
author_facet |
Dash Aditya P Ojha Vijay P Ghosh Susanta K Tiwari Satyanarayan Raghavendra Kamaraju |
author_sort |
Dash Aditya P |
title |
Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector Anopheles stephensi : a case study in Mangalore city, South India |
title_short |
Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector Anopheles stephensi : a case study in Mangalore city, South India |
title_full |
Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector Anopheles stephensi : a case study in Mangalore city, South India |
title_fullStr |
Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector Anopheles stephensi : a case study in Mangalore city, South India |
title_full_unstemmed |
Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector Anopheles stephensi : a case study in Mangalore city, South India |
title_sort |
reduced susceptibility to selected synthetic pyrethroids in urban malaria vector anopheles stephensi : a case study in mangalore city, south india |
publisher |
BMC |
publishDate |
2010 |
url |
https://doi.org/10.1186/1475-2875-9-179 https://doaj.org/article/d4c4016f64b84927b83f3fa5668518d8 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 9, Iss 1, p 179 (2010) |
op_relation |
http://www.malariajournal.com/content/9/1/179 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-179 1475-2875 https://doaj.org/article/d4c4016f64b84927b83f3fa5668518d8 |
op_doi |
https://doi.org/10.1186/1475-2875-9-179 |
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Malaria Journal |
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9 |
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179 |
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