Novel phenolic compound from Southern Ocean microalgae Chlorella sp. PR-1 and its antibacterial activity
Marine microalgae has been attracting the researcher’s attention for centuries. Development on microalgal research is majorly favoured by its medicinal, pharmaceutical or cosmeceutical properties. The advancement in the investigation related to microalgal products have been concentrated in the coast...
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Universidad de Concepción
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ftdoajarticles:oai:doaj.org/article:d3ddc304500849f1ac4e744414771a5a 2023-05-15T18:24:11+02:00 Novel phenolic compound from Southern Ocean microalgae Chlorella sp. PR-1 and its antibacterial activity Pratibha Gupta Aparna Banerjee Alexis Castillo Rajib Bandopadhyay 2021-06-01T00:00:00Z https://doaj.org/article/d3ddc304500849f1ac4e744414771a5a EN ES eng spa Universidad de Concepción https://gayanabotanica.cl/index.php/gb/article/view/351 https://doaj.org/toc/0016-5301 https://doaj.org/toc/0717-6643 0016-5301 0717-6643 https://doaj.org/article/d3ddc304500849f1ac4e744414771a5a Gayana: Botanica, Vol 78, Iss 1 (2021) Southern Ocean microalgae phenolic compound antibacterial activity Botany QK1-989 article 2021 ftdoajarticles 2022-12-31T11:23:16Z Marine microalgae has been attracting the researcher’s attention for centuries. Development on microalgal research is majorly favoured by its medicinal, pharmaceutical or cosmeceutical properties. The advancement in the investigation related to microalgal products have been concentrated in the coastal zones because of the greater supply of raw material. The Southern Ocean, highly productive and relatively poorly studied ecosystem, constitutes approximately 10% of the global volume of the oceans. In this study, marine microalgae Chlorella sp. PR-1 was isolated from the Southern Ocean (Indian Sector) for the identification of bioactive antibacterial compounds. The antimicrobial activity of this microalgal extracts was evaluated against three gram positive (Staphylococcus aureus, Bacillus licheniformis, and Bacillus subtilis) and three gram negative bacteria (Pseudomonas aeruginosa, Salmonella typhimurium, and Escherichia coli). The extract showing antibacterial activity was further purified by thin layer and column chromatography. The antimicrobial activity was again evaluated and confirmed with the purified fraction against the same bacteria. The identification of the functional groups in the purified fraction was performed by infrared spectroscopic analysis. Based on gas chromatographic and mass spectroscopic analysis, the principle bioactive compound was proved to be 2,4-bis (1,1-dimethylethyl)- phenol. Thus, the bioactive compound isolated from marine microalga of Southern Ocean origin may be a novel alternative source of antibacterials in the future. Article in Journal/Newspaper Southern Ocean Directory of Open Access Journals: DOAJ Articles Southern Ocean Indian |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English Spanish |
topic |
Southern Ocean microalgae phenolic compound antibacterial activity Botany QK1-989 |
spellingShingle |
Southern Ocean microalgae phenolic compound antibacterial activity Botany QK1-989 Pratibha Gupta Aparna Banerjee Alexis Castillo Rajib Bandopadhyay Novel phenolic compound from Southern Ocean microalgae Chlorella sp. PR-1 and its antibacterial activity |
topic_facet |
Southern Ocean microalgae phenolic compound antibacterial activity Botany QK1-989 |
description |
Marine microalgae has been attracting the researcher’s attention for centuries. Development on microalgal research is majorly favoured by its medicinal, pharmaceutical or cosmeceutical properties. The advancement in the investigation related to microalgal products have been concentrated in the coastal zones because of the greater supply of raw material. The Southern Ocean, highly productive and relatively poorly studied ecosystem, constitutes approximately 10% of the global volume of the oceans. In this study, marine microalgae Chlorella sp. PR-1 was isolated from the Southern Ocean (Indian Sector) for the identification of bioactive antibacterial compounds. The antimicrobial activity of this microalgal extracts was evaluated against three gram positive (Staphylococcus aureus, Bacillus licheniformis, and Bacillus subtilis) and three gram negative bacteria (Pseudomonas aeruginosa, Salmonella typhimurium, and Escherichia coli). The extract showing antibacterial activity was further purified by thin layer and column chromatography. The antimicrobial activity was again evaluated and confirmed with the purified fraction against the same bacteria. The identification of the functional groups in the purified fraction was performed by infrared spectroscopic analysis. Based on gas chromatographic and mass spectroscopic analysis, the principle bioactive compound was proved to be 2,4-bis (1,1-dimethylethyl)- phenol. Thus, the bioactive compound isolated from marine microalga of Southern Ocean origin may be a novel alternative source of antibacterials in the future. |
format |
Article in Journal/Newspaper |
author |
Pratibha Gupta Aparna Banerjee Alexis Castillo Rajib Bandopadhyay |
author_facet |
Pratibha Gupta Aparna Banerjee Alexis Castillo Rajib Bandopadhyay |
author_sort |
Pratibha Gupta |
title |
Novel phenolic compound from Southern Ocean microalgae Chlorella sp. PR-1 and its antibacterial activity |
title_short |
Novel phenolic compound from Southern Ocean microalgae Chlorella sp. PR-1 and its antibacterial activity |
title_full |
Novel phenolic compound from Southern Ocean microalgae Chlorella sp. PR-1 and its antibacterial activity |
title_fullStr |
Novel phenolic compound from Southern Ocean microalgae Chlorella sp. PR-1 and its antibacterial activity |
title_full_unstemmed |
Novel phenolic compound from Southern Ocean microalgae Chlorella sp. PR-1 and its antibacterial activity |
title_sort |
novel phenolic compound from southern ocean microalgae chlorella sp. pr-1 and its antibacterial activity |
publisher |
Universidad de Concepción |
publishDate |
2021 |
url |
https://doaj.org/article/d3ddc304500849f1ac4e744414771a5a |
geographic |
Southern Ocean Indian |
geographic_facet |
Southern Ocean Indian |
genre |
Southern Ocean |
genre_facet |
Southern Ocean |
op_source |
Gayana: Botanica, Vol 78, Iss 1 (2021) |
op_relation |
https://gayanabotanica.cl/index.php/gb/article/view/351 https://doaj.org/toc/0016-5301 https://doaj.org/toc/0717-6643 0016-5301 0717-6643 https://doaj.org/article/d3ddc304500849f1ac4e744414771a5a |
_version_ |
1766204521138094080 |