Evaluation of the genetic polymorphism of Plasmodium falciparum P126 protein (SERA or SERP) and its influence on naturally acquired specific antibody responses in malaria-infected individuals living in the Brazilian Amazon

• Published in: Malaria Journal
• Main Authors: Daniel-Ribeiro Cláudio T, Ferreira-Da-Cruz Maria de Fátima, de Simone Salvatore G, Morgado Mariza G, de Simone Thatiane S, Santos Fátima, Guimarães Monick, da Silva Bruno T, de Oliveira-Ferreira Joseli, Sallenave-Sales Selma, Pratt-Riccio Lilian, Zalis Mariano G, Camus Daniel, Banic Dalma M
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2008
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Serp
• Online Access: https://doi.org/10.1186/1475-2875-7-144; https://doaj.org/article/d3ae2f891d8447efb3c94bcc0012dc2a

Abstract Background The Plasmodium falciparum P126 protein is an asexual blood-stage malaria vaccine candidate antigen. Antibodies against P126 are able to inhibit parasite growth in vitro , and a major parasite-inhibitory epitope has been recently mapped to its 47 kDa N-terminal extremity (octamer...