The performance of an in-house loop-mediated isothermal amplification for the rapid detection of Mycobacterium tuberculosis in sputum samples in comparison with Xpert MTB/RIF, microscopy and culture

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: Benjawan Phetsuksiri, Wiphat Klayut, Janisara Rudeeaneksin, Sopa Srisungngam, Supranee Bunchoo, Sarawut Toonkomdang, Thanee Wongchai, Chie Nakajima, Yasuhiko Suzuki
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP)
• Subjects: lamp; tuberculosis; diagnosis; sputum; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Rif
• Online Access: https://doi.org/10.1590/s1678-9946202062036; https://doaj.org/article/d318c28f7d524019b80f488af5b1dff2

ABSTRACT Simple, low-cost and effective diagnostic tests for tuberculosis (TB) are needed especially in TB-high burden settings. The present study evaluated the performance of an in-house loop-mediated isothermal amplification (LAMP) for diagnosing TB by comparing it to Xpert MTB/RIF, microscopy and...