Prevalence of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates in Nepal
Background. Multidrug-resistant Klebsiella pneumoniae (MDR-KP) are becoming increasingly common over the world. The focus of this research was to get a quantitative assessment of K. pneumoniae and their multidrug resistance (MDR) profile in Nepal. Methods. Three electronic databases: PubMed, Google...
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ftdoajarticles:oai:doaj.org/article:d18b8cc9d06742438458a0321772c9da 2024-09-09T19:26:14+00:00 Prevalence of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates in Nepal Ranjeeta Odari Prabin Dawadi 2022-01-01T00:00:00Z https://doi.org/10.1155/2022/5309350 https://doaj.org/article/d18b8cc9d06742438458a0321772c9da EN eng Wiley http://dx.doi.org/10.1155/2022/5309350 https://doaj.org/toc/1687-9694 1687-9694 doi:10.1155/2022/5309350 https://doaj.org/article/d18b8cc9d06742438458a0321772c9da Journal of Tropical Medicine, Vol 2022 (2022) Arctic medicine. Tropical medicine RC955-962 article 2022 ftdoajarticles https://doi.org/10.1155/2022/5309350 2024-08-05T17:48:42Z Background. Multidrug-resistant Klebsiella pneumoniae (MDR-KP) are becoming increasingly common over the world. The focus of this research was to get a quantitative assessment of K. pneumoniae and their multidrug resistance (MDR) profile in Nepal. Methods. Three electronic databases: PubMed, Google Scholar, and Research4Life were used to search publications specifying K. pneumoniae infections and/or their MDR status from January 2015 to October 2021. Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines was followed for the review, and R language 4.1.1 was used for analysis. Depending upon heterogeneity of data, we used random model for pooled data to examine the prevalence of the organism and the multidrug resistance. Results. Evaluation included 16 studies, and the pooled estimation of K. pneumoniae in total clinical samples was 3% (95% CI; 0.01–0.05). In the meta-analysis, 14 studies were combined for determining the prevalence of K. pneumoniae in total positive clinical isolates which was 16% (95% CI: 0.11–0.20), while from 12 research studies, MDR status in the pathogen was found to be 64% (95% CI, 0.53–0.74). Conclusion. The MDR status of K. pneumoniae as well as the prevalence of the bacteria in Nepal was analyzed which showed alarming situation about administration of antibiotics and indicated choosing and developing reliable antibiotic strategies. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Prisma ENVELOPE(-58.767,-58.767,-69.200,-69.200) Journal of Tropical Medicine 2022 1 6 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Ranjeeta Odari Prabin Dawadi Prevalence of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates in Nepal |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
Background. Multidrug-resistant Klebsiella pneumoniae (MDR-KP) are becoming increasingly common over the world. The focus of this research was to get a quantitative assessment of K. pneumoniae and their multidrug resistance (MDR) profile in Nepal. Methods. Three electronic databases: PubMed, Google Scholar, and Research4Life were used to search publications specifying K. pneumoniae infections and/or their MDR status from January 2015 to October 2021. Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines was followed for the review, and R language 4.1.1 was used for analysis. Depending upon heterogeneity of data, we used random model for pooled data to examine the prevalence of the organism and the multidrug resistance. Results. Evaluation included 16 studies, and the pooled estimation of K. pneumoniae in total clinical samples was 3% (95% CI; 0.01–0.05). In the meta-analysis, 14 studies were combined for determining the prevalence of K. pneumoniae in total positive clinical isolates which was 16% (95% CI: 0.11–0.20), while from 12 research studies, MDR status in the pathogen was found to be 64% (95% CI, 0.53–0.74). Conclusion. The MDR status of K. pneumoniae as well as the prevalence of the bacteria in Nepal was analyzed which showed alarming situation about administration of antibiotics and indicated choosing and developing reliable antibiotic strategies. |
format |
Article in Journal/Newspaper |
author |
Ranjeeta Odari Prabin Dawadi |
author_facet |
Ranjeeta Odari Prabin Dawadi |
author_sort |
Ranjeeta Odari |
title |
Prevalence of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates in Nepal |
title_short |
Prevalence of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates in Nepal |
title_full |
Prevalence of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates in Nepal |
title_fullStr |
Prevalence of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates in Nepal |
title_full_unstemmed |
Prevalence of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates in Nepal |
title_sort |
prevalence of multidrug-resistant klebsiella pneumoniae clinical isolates in nepal |
publisher |
Wiley |
publishDate |
2022 |
url |
https://doi.org/10.1155/2022/5309350 https://doaj.org/article/d18b8cc9d06742438458a0321772c9da |
long_lat |
ENVELOPE(-58.767,-58.767,-69.200,-69.200) |
geographic |
Arctic Prisma |
geographic_facet |
Arctic Prisma |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2022 (2022) |
op_relation |
http://dx.doi.org/10.1155/2022/5309350 https://doaj.org/toc/1687-9694 1687-9694 doi:10.1155/2022/5309350 https://doaj.org/article/d18b8cc9d06742438458a0321772c9da |
op_doi |
https://doi.org/10.1155/2022/5309350 |
container_title |
Journal of Tropical Medicine |
container_volume |
2022 |
container_start_page |
1 |
op_container_end_page |
6 |
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1809895884596445184 |