Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts.
Lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminths, and trachoma are the five most prevalent neglected tropical diseases in the world, and each is frequently treated with mass drug administrations. We performed a survey of neglected tropical diseases experts to elicit...
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ftdoajarticles:oai:doaj.org/article:d1542c31094f4d94aed3b79ce8838098 2023-05-15T15:16:28+02:00 Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. Jeremy D Keenan Peter J Hotez Abdou Amza Nicole E Stoller Bruce D Gaynor Travis C Porco Thomas M Lietman 2013-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0002562 https://doaj.org/article/d1542c31094f4d94aed3b79ce8838098 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3855072?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002562 https://doaj.org/article/d1542c31094f4d94aed3b79ce8838098 PLoS Neglected Tropical Diseases, Vol 7, Iss 12, p e2562 (2013) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2013 ftdoajarticles https://doi.org/10.1371/journal.pntd.0002562 2022-12-31T14:05:25Z Lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminths, and trachoma are the five most prevalent neglected tropical diseases in the world, and each is frequently treated with mass drug administrations. We performed a survey of neglected tropical diseases experts to elicit their opinions on the role of mass drug administrations for the elimination of these infections.We sent an online survey to corresponding authors who had published an article about a neglected tropical disease from 2007 to 2011. Of 825 unique authors who were invited to complete the survey, 365 (44.2%) responded, including 234 (28.4%) who answered questions regarding one of the five most prevalent neglected tropical diseases. Respondents had varying opinions about the goals of programmatic activities for their chosen neglected tropical disease, with elimination or eradication identified as the most important goal by 87% of lymphatic filariasis respondents, 66% of onchocerciasis respondents, 55% of trachoma respondents, 24% of schistosomiasis respondents, and 21% of soil-transmitted helminth respondents. Mass drug administrations, other non-medication health measures, and education were generally thought to be more important for elimination than vector control, development of a new tool, or the presence of a secular trend. Drug resistance was thought to be a major limitation of mass drug administrations for all five neglected tropical diseases. Over half of respondents for lymphatic filariasis and trachoma thought that repeated mass drug administrations could eliminate infection within ten years of the initiation of mass treatments.Respondents for lymphatic filariasis, onchocerciasis, and trachoma were more enthusiastic about the prospects of elimination and eradication than were respondents for schistosomiasis or soil-transmitted helminths. Mass drug administrations were generally believed to be among the most important factors for the success of elimination efforts for each of the five neglected tropical diseases, ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 7 12 e2562 |
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Directory of Open Access Journals: DOAJ Articles |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Jeremy D Keenan Peter J Hotez Abdou Amza Nicole E Stoller Bruce D Gaynor Travis C Porco Thomas M Lietman Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminths, and trachoma are the five most prevalent neglected tropical diseases in the world, and each is frequently treated with mass drug administrations. We performed a survey of neglected tropical diseases experts to elicit their opinions on the role of mass drug administrations for the elimination of these infections.We sent an online survey to corresponding authors who had published an article about a neglected tropical disease from 2007 to 2011. Of 825 unique authors who were invited to complete the survey, 365 (44.2%) responded, including 234 (28.4%) who answered questions regarding one of the five most prevalent neglected tropical diseases. Respondents had varying opinions about the goals of programmatic activities for their chosen neglected tropical disease, with elimination or eradication identified as the most important goal by 87% of lymphatic filariasis respondents, 66% of onchocerciasis respondents, 55% of trachoma respondents, 24% of schistosomiasis respondents, and 21% of soil-transmitted helminth respondents. Mass drug administrations, other non-medication health measures, and education were generally thought to be more important for elimination than vector control, development of a new tool, or the presence of a secular trend. Drug resistance was thought to be a major limitation of mass drug administrations for all five neglected tropical diseases. Over half of respondents for lymphatic filariasis and trachoma thought that repeated mass drug administrations could eliminate infection within ten years of the initiation of mass treatments.Respondents for lymphatic filariasis, onchocerciasis, and trachoma were more enthusiastic about the prospects of elimination and eradication than were respondents for schistosomiasis or soil-transmitted helminths. Mass drug administrations were generally believed to be among the most important factors for the success of elimination efforts for each of the five neglected tropical diseases, ... |
format |
Article in Journal/Newspaper |
author |
Jeremy D Keenan Peter J Hotez Abdou Amza Nicole E Stoller Bruce D Gaynor Travis C Porco Thomas M Lietman |
author_facet |
Jeremy D Keenan Peter J Hotez Abdou Amza Nicole E Stoller Bruce D Gaynor Travis C Porco Thomas M Lietman |
author_sort |
Jeremy D Keenan |
title |
Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. |
title_short |
Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. |
title_full |
Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. |
title_fullStr |
Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. |
title_full_unstemmed |
Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. |
title_sort |
elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2013 |
url |
https://doi.org/10.1371/journal.pntd.0002562 https://doaj.org/article/d1542c31094f4d94aed3b79ce8838098 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 7, Iss 12, p e2562 (2013) |
op_relation |
http://europepmc.org/articles/PMC3855072?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002562 https://doaj.org/article/d1542c31094f4d94aed3b79ce8838098 |
op_doi |
https://doi.org/10.1371/journal.pntd.0002562 |
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PLoS Neglected Tropical Diseases |
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7 |
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12 |
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e2562 |
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