From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide.
The development of insecticide resistance is becoming a threat to many arboviruses control programs worldwide. While this has been attributed to the indiscriminate use of insecticide, a more theoretical study is apparently not available. Using in-silico experiments, we investigated the effects of tw...
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ftdoajarticles:oai:doaj.org/article:d10586ad796d4239b601dda19ad8fd5a 2023-05-15T15:03:02+02:00 From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. Helio Schechtman Denise Valle Max O Souza 2020-11-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0008862 https://doaj.org/article/d10586ad796d4239b601dda19ad8fd5a EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0008862 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008862 https://doaj.org/article/d10586ad796d4239b601dda19ad8fd5a PLoS Neglected Tropical Diseases, Vol 14, Iss 11, p e0008862 (2020) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.1371/journal.pntd.0008862 2022-12-31T05:52:29Z The development of insecticide resistance is becoming a threat to many arboviruses control programs worldwide. While this has been attributed to the indiscriminate use of insecticide, a more theoretical study is apparently not available. Using in-silico experiments, we investigated the effects of two different policies: one used by the Brazilian Ministry of Health (which follows the World Health Organization protocol) and a more permissive one, akin to those employed by various gated communities and private companies. The results show that the public policy does not lead to resistance fixation. On the other hand, permissive application of adulticide, such as intensive domestic use mainly during epidemic periods, might lead to the fixation of a resistant population, even when resistance is associated with moderate fitness costs. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 14 11 e0008862 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Helio Schechtman Denise Valle Max O Souza From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
The development of insecticide resistance is becoming a threat to many arboviruses control programs worldwide. While this has been attributed to the indiscriminate use of insecticide, a more theoretical study is apparently not available. Using in-silico experiments, we investigated the effects of two different policies: one used by the Brazilian Ministry of Health (which follows the World Health Organization protocol) and a more permissive one, akin to those employed by various gated communities and private companies. The results show that the public policy does not lead to resistance fixation. On the other hand, permissive application of adulticide, such as intensive domestic use mainly during epidemic periods, might lead to the fixation of a resistant population, even when resistance is associated with moderate fitness costs. |
format |
Article in Journal/Newspaper |
author |
Helio Schechtman Denise Valle Max O Souza |
author_facet |
Helio Schechtman Denise Valle Max O Souza |
author_sort |
Helio Schechtman |
title |
From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. |
title_short |
From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. |
title_full |
From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. |
title_fullStr |
From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. |
title_full_unstemmed |
From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. |
title_sort |
from resistance to persistence: insights of a mathematical model on the indiscriminate use of insecticide. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2020 |
url |
https://doi.org/10.1371/journal.pntd.0008862 https://doaj.org/article/d10586ad796d4239b601dda19ad8fd5a |
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Arctic |
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Arctic |
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Arctic |
genre_facet |
Arctic |
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PLoS Neglected Tropical Diseases, Vol 14, Iss 11, p e0008862 (2020) |
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https://doi.org/10.1371/journal.pntd.0008862 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008862 https://doaj.org/article/d10586ad796d4239b601dda19ad8fd5a |
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https://doi.org/10.1371/journal.pntd.0008862 |
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PLOS Neglected Tropical Diseases |
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