Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012
Introduction Surveillance of nosocomial infections (NIs) is an essential part of quality patient care; however, there are few reports of National Healthcare Safety Network (NHSN) surveillance in neonatal intensive care units (NICUs) and none in developing countries. The purpose of this study was to...
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ftdoajarticles:oai:doaj.org/article:d01267bcd23645c588ca197a217f1e2e 2023-05-15T15:10:44+02:00 Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 Jane Eire Urzedo Maria Margarida Morena Domingos Levenhagen Reginaldo Santos Pedroso Vânia Olivetti Steffen Abdallah Sebastiana Silva Sabino Denise Von Dolinger Brito 2014-06-01T00:00:00Z https://doi.org/10.1590/0037-8682-0101-2014 https://doaj.org/article/d01267bcd23645c588ca197a217f1e2e EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300321&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0101-2014 https://doaj.org/article/d01267bcd23645c588ca197a217f1e2e Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 3, Pp 321-326 (2014) Nosocomial infection Surveillance system Critical neonates Arctic medicine. Tropical medicine RC955-962 article 2014 ftdoajarticles https://doi.org/10.1590/0037-8682-0101-2014 2022-12-30T21:27:31Z Introduction Surveillance of nosocomial infections (NIs) is an essential part of quality patient care; however, there are few reports of National Healthcare Safety Network (NHSN) surveillance in neonatal intensive care units (NICUs) and none in developing countries. The purpose of this study was to report the incidence of NIs, causative organisms, and antimicrobial susceptibility patterns in a large cohort of neonates admitted to the NICU during a 16-year period. Methods The patients were followed 5 times per week from birth to discharge or death, and epidemiological surveillance was conducted according to the NHSN. Results From January 1997 to December 2012, 4,615 neonates, representing 62,412 patient-days, were admitted to the NICU. The device-associated infection rates were as follows: 17.3 primary bloodstream infections per 1,000 central line-days and 3.2 pneumonia infections per 1,000 ventilator-days. A total of 1,182 microorganisms were isolated from sterile body site cultures in 902 neonates. Coagulase-negative staphylococci (CoNS) (34.3%) and Staphylococcus aureus (15.6%) were the most common etiologic agents isolated from cultures. The incidences of oxacillin-resistant CoNS and Staphylococcus aureus were 86.4% and 28.3%, respectively. Conclusions The most important NI remains bloodstream infection with staphylococci as the predominant pathogens, observed at much higher rates than those reported in the literature. Multiresistant microorganisms, especially oxacillin-resistant staphylococci and gram-negative bacilli resistant to cephalosporin were frequently found. Furthermore, by promoting strict hygiene measures and meticulous care of the infected infants, the process itself of evaluating the causative organisms was valuable. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 47 3 321 326 |
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English |
topic |
Nosocomial infection Surveillance system Critical neonates Arctic medicine. Tropical medicine RC955-962 |
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Nosocomial infection Surveillance system Critical neonates Arctic medicine. Tropical medicine RC955-962 Jane Eire Urzedo Maria Margarida Morena Domingos Levenhagen Reginaldo Santos Pedroso Vânia Olivetti Steffen Abdallah Sebastiana Silva Sabino Denise Von Dolinger Brito Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
topic_facet |
Nosocomial infection Surveillance system Critical neonates Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction Surveillance of nosocomial infections (NIs) is an essential part of quality patient care; however, there are few reports of National Healthcare Safety Network (NHSN) surveillance in neonatal intensive care units (NICUs) and none in developing countries. The purpose of this study was to report the incidence of NIs, causative organisms, and antimicrobial susceptibility patterns in a large cohort of neonates admitted to the NICU during a 16-year period. Methods The patients were followed 5 times per week from birth to discharge or death, and epidemiological surveillance was conducted according to the NHSN. Results From January 1997 to December 2012, 4,615 neonates, representing 62,412 patient-days, were admitted to the NICU. The device-associated infection rates were as follows: 17.3 primary bloodstream infections per 1,000 central line-days and 3.2 pneumonia infections per 1,000 ventilator-days. A total of 1,182 microorganisms were isolated from sterile body site cultures in 902 neonates. Coagulase-negative staphylococci (CoNS) (34.3%) and Staphylococcus aureus (15.6%) were the most common etiologic agents isolated from cultures. The incidences of oxacillin-resistant CoNS and Staphylococcus aureus were 86.4% and 28.3%, respectively. Conclusions The most important NI remains bloodstream infection with staphylococci as the predominant pathogens, observed at much higher rates than those reported in the literature. Multiresistant microorganisms, especially oxacillin-resistant staphylococci and gram-negative bacilli resistant to cephalosporin were frequently found. Furthermore, by promoting strict hygiene measures and meticulous care of the infected infants, the process itself of evaluating the causative organisms was valuable. |
format |
Article in Journal/Newspaper |
author |
Jane Eire Urzedo Maria Margarida Morena Domingos Levenhagen Reginaldo Santos Pedroso Vânia Olivetti Steffen Abdallah Sebastiana Silva Sabino Denise Von Dolinger Brito |
author_facet |
Jane Eire Urzedo Maria Margarida Morena Domingos Levenhagen Reginaldo Santos Pedroso Vânia Olivetti Steffen Abdallah Sebastiana Silva Sabino Denise Von Dolinger Brito |
author_sort |
Jane Eire Urzedo |
title |
Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
title_short |
Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
title_full |
Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
title_fullStr |
Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
title_full_unstemmed |
Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
title_sort |
nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2014 |
url |
https://doi.org/10.1590/0037-8682-0101-2014 https://doaj.org/article/d01267bcd23645c588ca197a217f1e2e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 3, Pp 321-326 (2014) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300321&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0101-2014 https://doaj.org/article/d01267bcd23645c588ca197a217f1e2e |
op_doi |
https://doi.org/10.1590/0037-8682-0101-2014 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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47 |
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3 |
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321 |
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326 |
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