The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital
ABSTRACT Objective To determine rates of retention, antiretroviral therapy (ART) use, and viral suppression in an adult cohort from a public tertiary referral hospital in the city of Buenos Aires, Argentina. Methods HIV-positive ART-naïve patients ≥ 18 years old starting care 2011-2013 contributed d...
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ftdoajarticles:oai:doaj.org/article:cfce1ae0be2e4ad09845a674e217137f 2023-05-15T15:12:05+02:00 The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital Carina Cesar Gabriela Blugerman José Antonio Valiente Peter Rebeiro Omar Sued Valeria Fink Mariana Romero Soto Roberto Cillis Cleyton Yamamoto Carlos Falistocco Pedro Cahn Héctor Pérez https://doaj.org/article/cfce1ae0be2e4ad09845a674e217137f EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892016001200448&lng=en&tlng=en https://doaj.org/toc/1680-5348 1680-5348 https://doaj.org/article/cfce1ae0be2e4ad09845a674e217137f Revista Panamericana de Salud Pública, Vol 40, Iss 6, Pp 448-454 VIH terapia antirretroviral altamente activa resultado del tratamiento continuidad de la atención al paciente Argentina Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article ftdoajarticles 2022-12-31T12:01:09Z ABSTRACT Objective To determine rates of retention, antiretroviral therapy (ART) use, and viral suppression in an adult cohort from a public tertiary referral hospital in the city of Buenos Aires, Argentina. Methods HIV-positive ART-naïve patients ≥ 18 years old starting care 2011-2013 contributed data until the end of 2014. Three outcomes were assessed in 2014: retention in care, ART use, and viral suppression. Patient characteristics associated with each outcome were assessed through logistic regression. Results A total of 1 031 patients were included. By the end of 2014, 1.5% had died and 14.8% were transferred to a different center. Of the remaining 859 patients, 563 (65.5%) were retained in 2014. Among those retained, 459 (81.5%) were on ART in 2014. Of those 459 on ART, 270 (58.8%) were virologically suppressed. Younger age was associated with lower retention (OR (odds ratio): 0.67; 95% CI (confidence interval): 0.44-0.92 for ≥ 35 vs. < 35 years), but unrelated with ART use or viral suppression. Low CD4 count at first visit was associated with ART use (OR: 35.72 for CD4 < 200, 7.13 for CD4 200-499 vs. ≥ 500, P < 0.001) and with virologic suppression (OR: 2.17 for CD4 < 200, 2.46 for CD4 200-499 vs. ≥ 500, P: 0.023). Conclusions Our hospital in Buenos Aires is still below the recommended 90-90-90 targets of the Joint United Nations Programme on HIV/AIDS (UNAIDS) for ART use and viral suppression. We found a major gap in retention in care. Identifying younger age as being associated with worse retention will help in the design of targeted interventions. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Argentina |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish Portuguese |
topic |
VIH terapia antirretroviral altamente activa resultado del tratamiento continuidad de la atención al paciente Argentina Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
VIH terapia antirretroviral altamente activa resultado del tratamiento continuidad de la atención al paciente Argentina Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Carina Cesar Gabriela Blugerman José Antonio Valiente Peter Rebeiro Omar Sued Valeria Fink Mariana Romero Soto Roberto Cillis Cleyton Yamamoto Carlos Falistocco Pedro Cahn Héctor Pérez The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital |
topic_facet |
VIH terapia antirretroviral altamente activa resultado del tratamiento continuidad de la atención al paciente Argentina Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
ABSTRACT Objective To determine rates of retention, antiretroviral therapy (ART) use, and viral suppression in an adult cohort from a public tertiary referral hospital in the city of Buenos Aires, Argentina. Methods HIV-positive ART-naïve patients ≥ 18 years old starting care 2011-2013 contributed data until the end of 2014. Three outcomes were assessed in 2014: retention in care, ART use, and viral suppression. Patient characteristics associated with each outcome were assessed through logistic regression. Results A total of 1 031 patients were included. By the end of 2014, 1.5% had died and 14.8% were transferred to a different center. Of the remaining 859 patients, 563 (65.5%) were retained in 2014. Among those retained, 459 (81.5%) were on ART in 2014. Of those 459 on ART, 270 (58.8%) were virologically suppressed. Younger age was associated with lower retention (OR (odds ratio): 0.67; 95% CI (confidence interval): 0.44-0.92 for ≥ 35 vs. < 35 years), but unrelated with ART use or viral suppression. Low CD4 count at first visit was associated with ART use (OR: 35.72 for CD4 < 200, 7.13 for CD4 200-499 vs. ≥ 500, P < 0.001) and with virologic suppression (OR: 2.17 for CD4 < 200, 2.46 for CD4 200-499 vs. ≥ 500, P: 0.023). Conclusions Our hospital in Buenos Aires is still below the recommended 90-90-90 targets of the Joint United Nations Programme on HIV/AIDS (UNAIDS) for ART use and viral suppression. We found a major gap in retention in care. Identifying younger age as being associated with worse retention will help in the design of targeted interventions. |
format |
Article in Journal/Newspaper |
author |
Carina Cesar Gabriela Blugerman José Antonio Valiente Peter Rebeiro Omar Sued Valeria Fink Mariana Romero Soto Roberto Cillis Cleyton Yamamoto Carlos Falistocco Pedro Cahn Héctor Pérez |
author_facet |
Carina Cesar Gabriela Blugerman José Antonio Valiente Peter Rebeiro Omar Sued Valeria Fink Mariana Romero Soto Roberto Cillis Cleyton Yamamoto Carlos Falistocco Pedro Cahn Héctor Pérez |
author_sort |
Carina Cesar |
title |
The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital |
title_short |
The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital |
title_full |
The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital |
title_fullStr |
The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital |
title_full_unstemmed |
The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital |
title_sort |
hiv care cascade in buenos aires, argentina: results in a tertiary referral hospital |
publisher |
Pan American Health Organization |
url |
https://doaj.org/article/cfce1ae0be2e4ad09845a674e217137f |
geographic |
Arctic Argentina |
geographic_facet |
Arctic Argentina |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 40, Iss 6, Pp 448-454 |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892016001200448&lng=en&tlng=en https://doaj.org/toc/1680-5348 1680-5348 https://doaj.org/article/cfce1ae0be2e4ad09845a674e217137f |
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1766342827817566208 |