Clinical manifestations of chikungunya among university professors and staff in Santo Domingo, the Dominican Republic
ABSTRACT Objective To further characterize chikungunya virus infection and its associated clinical manifestations, using a sample of university professors and staff in Santo Domingo, the Dominican Republic. Methods A cross-sectional study with quota sampling by department was performed to obtain a c...
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ftdoajarticles:oai:doaj.org/article:cfbc1ab14ba6406799c6208070cf53dc 2023-05-15T15:16:04+02:00 Clinical manifestations of chikungunya among university professors and staff in Santo Domingo, the Dominican Republic Michael A. Zingman Amarilis Then Paulino Matilde Peguero Payano 2017-08-01T00:00:00Z https://doaj.org/article/cfbc1ab14ba6406799c6208070cf53dc EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892017000100243&lng=en&tlng=en https://doaj.org/toc/1680-5348 1680-5348 https://doaj.org/article/cfbc1ab14ba6406799c6208070cf53dc Revista Panamericana de Salud Pública, Vol 41, Iss 0 (2017) Virus chikungunya enfermedades transmisibles Aedes aegypti Aedes albopictus República Dominicana Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2017 ftdoajarticles 2022-12-31T14:08:40Z ABSTRACT Objective To further characterize chikungunya virus infection and its associated clinical manifestations, using a sample of university professors and staff in Santo Domingo, the Dominican Republic. Methods A cross-sectional study with quota sampling by department was performed to obtain a convenience sample of professors (n = 736) and staff (n = 499) at the Universidad Autónoma de Santo Domingo. Surveys were used to collect demographic and infection data during the fall term of 2014. Univariate and bivariate analyses were carried out to quantify infection and clinical manifestation prevalence and to assess relationships of these outcomes with age, sex, and acute phase duration. Results Of 1 236 participants, 49% reported infection (professors = 41%; staff = 61%). Of these, 53% also reported the presence of chronic effects, largely arthralgia (48%). Significant relationships were observed between reported infection and sex (P = 0.023), age (P < 0.001), and occupation (P < 0.001). More headache (P = 0.008) and edema (P < 0.001) in females, more headache (P = 0.005) in younger subjects, and more myalgia (P = 0.006) in those with longer acute symptoms were found. Additionally, more chronic arthralgia (P < 0.001; P = 0.003) and chronic edema (P < 0.001; P = 0.001) in females and older subjects, and more chronic myalgia (P = 0.041) and chronic edema (P = 0.037) in those with longer acute symptoms were observed. Conclusions To the authors knowledge, this is the first population-based chikungunya prevalence study in the Dominican Republic, and the first to explore clinical manifestations in a university setting. The findings reflect results from studies following the 2005 – 2006 Reunion Island outbreak: prevalence of infection and chronic arthralgia, as well as associations with sex, age, and acute intensity. Longitudinal research can provide further insight into these effects. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English Spanish Portuguese |
topic |
Virus chikungunya enfermedades transmisibles Aedes aegypti Aedes albopictus República Dominicana Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Virus chikungunya enfermedades transmisibles Aedes aegypti Aedes albopictus República Dominicana Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Michael A. Zingman Amarilis Then Paulino Matilde Peguero Payano Clinical manifestations of chikungunya among university professors and staff in Santo Domingo, the Dominican Republic |
topic_facet |
Virus chikungunya enfermedades transmisibles Aedes aegypti Aedes albopictus República Dominicana Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
ABSTRACT Objective To further characterize chikungunya virus infection and its associated clinical manifestations, using a sample of university professors and staff in Santo Domingo, the Dominican Republic. Methods A cross-sectional study with quota sampling by department was performed to obtain a convenience sample of professors (n = 736) and staff (n = 499) at the Universidad Autónoma de Santo Domingo. Surveys were used to collect demographic and infection data during the fall term of 2014. Univariate and bivariate analyses were carried out to quantify infection and clinical manifestation prevalence and to assess relationships of these outcomes with age, sex, and acute phase duration. Results Of 1 236 participants, 49% reported infection (professors = 41%; staff = 61%). Of these, 53% also reported the presence of chronic effects, largely arthralgia (48%). Significant relationships were observed between reported infection and sex (P = 0.023), age (P < 0.001), and occupation (P < 0.001). More headache (P = 0.008) and edema (P < 0.001) in females, more headache (P = 0.005) in younger subjects, and more myalgia (P = 0.006) in those with longer acute symptoms were found. Additionally, more chronic arthralgia (P < 0.001; P = 0.003) and chronic edema (P < 0.001; P = 0.001) in females and older subjects, and more chronic myalgia (P = 0.041) and chronic edema (P = 0.037) in those with longer acute symptoms were observed. Conclusions To the authors knowledge, this is the first population-based chikungunya prevalence study in the Dominican Republic, and the first to explore clinical manifestations in a university setting. The findings reflect results from studies following the 2005 – 2006 Reunion Island outbreak: prevalence of infection and chronic arthralgia, as well as associations with sex, age, and acute intensity. Longitudinal research can provide further insight into these effects. |
format |
Article in Journal/Newspaper |
author |
Michael A. Zingman Amarilis Then Paulino Matilde Peguero Payano |
author_facet |
Michael A. Zingman Amarilis Then Paulino Matilde Peguero Payano |
author_sort |
Michael A. Zingman |
title |
Clinical manifestations of chikungunya among university professors and staff in Santo Domingo, the Dominican Republic |
title_short |
Clinical manifestations of chikungunya among university professors and staff in Santo Domingo, the Dominican Republic |
title_full |
Clinical manifestations of chikungunya among university professors and staff in Santo Domingo, the Dominican Republic |
title_fullStr |
Clinical manifestations of chikungunya among university professors and staff in Santo Domingo, the Dominican Republic |
title_full_unstemmed |
Clinical manifestations of chikungunya among university professors and staff in Santo Domingo, the Dominican Republic |
title_sort |
clinical manifestations of chikungunya among university professors and staff in santo domingo, the dominican republic |
publisher |
Pan American Health Organization |
publishDate |
2017 |
url |
https://doaj.org/article/cfbc1ab14ba6406799c6208070cf53dc |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 41, Iss 0 (2017) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892017000100243&lng=en&tlng=en https://doaj.org/toc/1680-5348 1680-5348 https://doaj.org/article/cfbc1ab14ba6406799c6208070cf53dc |
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1766346382815264768 |