Herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in São Paulo, Brazil Infecções por herpes simplex tipo 2 durante a gestação: excreção assintomática do vírus durante o parto e estudo soroepidemiológico de duas populações socioeconomicamente distintas
The objective of the present study was to estimate the prevalence of herpes simplex virus type 2 (HSV 2) antibodies in child bearing women of 2 Brazilian populations with different socioeconomic status and to determine the risk of neonatal HSV exposure by means of maternal cultures at the onset of l...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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1993
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ftdoajarticles:oai:doaj.org/article:cef310a21ddf41d89a8d599e52e26551 2024-09-09T19:28:35+00:00 Herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in São Paulo, Brazil Infecções por herpes simplex tipo 2 durante a gestação: excreção assintomática do vírus durante o parto e estudo soroepidemiológico de duas populações socioeconomicamente distintas Adriana Weinberg Cynthia L.M. Canto Claudio S. Pannuti Wu N. Kwang Sidney A.L. Garcia Marcelo Zugaib 1993-06-01T00:00:00Z https://doi.org/10.1590/S0036-46651993000300011 https://doaj.org/article/cef310a21ddf41d89a8d599e52e26551 EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651993000300011 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651993000300011 0036-4665 1678-9946 https://doaj.org/article/cef310a21ddf41d89a8d599e52e26551 Revista do Instituto de Medicina Tropical de São Paulo, Vol 35, Iss 3, Pp 285-290 (1993) Herpes simplex Genital herpes Pregnancy Neonatal herpes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1993 ftdoajarticles https://doi.org/10.1590/S0036-46651993000300011 2024-08-05T17:49:30Z The objective of the present study was to estimate the prevalence of herpes simplex virus type 2 (HSV 2) antibodies in child bearing women of 2 Brazilian populations with different socioeconomic status and to determine the risk of neonatal HSV exposure by means of maternal cultures at the onset of labor. The study was conducted at 2 hospitals: A, serving very low income patients and B, serving middle socioeconomic class. 173 participants from group A and 127 from B answered a questionnaire which showed that the patients had similar ages (27.7 and 26.8 years, respectively) but differed with regard to socioeconomic status, age at first intercourse (18.6 vs 20.6 years), number of sex partners (1.5 vs 1.2) and previous sexually transmitted diseases (15% vs. 1.5%). History of genital herpes was given by 11% of group A participants and by a similar number, 7%, of patients from group B. In addition, 200 serum samples from population A and 455 from B were tested by ELISA for and HSV antibodies and 92% and 86%, respectively, were found to be positive. Sixty seropositive samples from group A and 90 from B were further analyzed by Western blot, which showed the presence of type 2 specific antibodies in 46% and 36%, respectively, suggesting an overall HSV 2 prevalence of 42% in group A and 31% in B. Cervical specimens were obtained for culture from 299 asymptomatic patients of population A and 313 of B. HSV was isolated from one specimen in each group, indicating a 0.3% incidence of asymptomatic viral excretion in both populations. In conclusion, the prevalence of type 2 antibodies in childbearing women was very high, but it did not differ with the socioeconomic status. The risk of HSV perinatal transmission was also similar in the 2 study populations and it was comparable with the data from developed countries. Our findings do not indicate the need of special screening programs for asymptomatic HSV excretion in Brazilian pregnant women. O objetivo deste estudo constou em determinar a prevalência dos anticorpos anti virus ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 35 3 285 290 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
topic |
Herpes simplex Genital herpes Pregnancy Neonatal herpes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Herpes simplex Genital herpes Pregnancy Neonatal herpes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Adriana Weinberg Cynthia L.M. Canto Claudio S. Pannuti Wu N. Kwang Sidney A.L. Garcia Marcelo Zugaib Herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in São Paulo, Brazil Infecções por herpes simplex tipo 2 durante a gestação: excreção assintomática do vírus durante o parto e estudo soroepidemiológico de duas populações socioeconomicamente distintas |
topic_facet |
Herpes simplex Genital herpes Pregnancy Neonatal herpes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
The objective of the present study was to estimate the prevalence of herpes simplex virus type 2 (HSV 2) antibodies in child bearing women of 2 Brazilian populations with different socioeconomic status and to determine the risk of neonatal HSV exposure by means of maternal cultures at the onset of labor. The study was conducted at 2 hospitals: A, serving very low income patients and B, serving middle socioeconomic class. 173 participants from group A and 127 from B answered a questionnaire which showed that the patients had similar ages (27.7 and 26.8 years, respectively) but differed with regard to socioeconomic status, age at first intercourse (18.6 vs 20.6 years), number of sex partners (1.5 vs 1.2) and previous sexually transmitted diseases (15% vs. 1.5%). History of genital herpes was given by 11% of group A participants and by a similar number, 7%, of patients from group B. In addition, 200 serum samples from population A and 455 from B were tested by ELISA for and HSV antibodies and 92% and 86%, respectively, were found to be positive. Sixty seropositive samples from group A and 90 from B were further analyzed by Western blot, which showed the presence of type 2 specific antibodies in 46% and 36%, respectively, suggesting an overall HSV 2 prevalence of 42% in group A and 31% in B. Cervical specimens were obtained for culture from 299 asymptomatic patients of population A and 313 of B. HSV was isolated from one specimen in each group, indicating a 0.3% incidence of asymptomatic viral excretion in both populations. In conclusion, the prevalence of type 2 antibodies in childbearing women was very high, but it did not differ with the socioeconomic status. The risk of HSV perinatal transmission was also similar in the 2 study populations and it was comparable with the data from developed countries. Our findings do not indicate the need of special screening programs for asymptomatic HSV excretion in Brazilian pregnant women. O objetivo deste estudo constou em determinar a prevalência dos anticorpos anti virus ... |
format |
Article in Journal/Newspaper |
author |
Adriana Weinberg Cynthia L.M. Canto Claudio S. Pannuti Wu N. Kwang Sidney A.L. Garcia Marcelo Zugaib |
author_facet |
Adriana Weinberg Cynthia L.M. Canto Claudio S. Pannuti Wu N. Kwang Sidney A.L. Garcia Marcelo Zugaib |
author_sort |
Adriana Weinberg |
title |
Herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in São Paulo, Brazil Infecções por herpes simplex tipo 2 durante a gestação: excreção assintomática do vírus durante o parto e estudo soroepidemiológico de duas populações socioeconomicamente distintas |
title_short |
Herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in São Paulo, Brazil Infecções por herpes simplex tipo 2 durante a gestação: excreção assintomática do vírus durante o parto e estudo soroepidemiológico de duas populações socioeconomicamente distintas |
title_full |
Herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in São Paulo, Brazil Infecções por herpes simplex tipo 2 durante a gestação: excreção assintomática do vírus durante o parto e estudo soroepidemiológico de duas populações socioeconomicamente distintas |
title_fullStr |
Herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in São Paulo, Brazil Infecções por herpes simplex tipo 2 durante a gestação: excreção assintomática do vírus durante o parto e estudo soroepidemiológico de duas populações socioeconomicamente distintas |
title_full_unstemmed |
Herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in São Paulo, Brazil Infecções por herpes simplex tipo 2 durante a gestação: excreção assintomática do vírus durante o parto e estudo soroepidemiológico de duas populações socioeconomicamente distintas |
title_sort |
herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in são paulo, brazil infecções por herpes simplex tipo 2 durante a gestação: excreção assintomática do vírus durante o parto e estudo soroepidemiológico de duas populações socioeconomicamente distintas |
publisher |
Universidade de São Paulo (USP) |
publishDate |
1993 |
url |
https://doi.org/10.1590/S0036-46651993000300011 https://doaj.org/article/cef310a21ddf41d89a8d599e52e26551 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 35, Iss 3, Pp 285-290 (1993) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651993000300011 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651993000300011 0036-4665 1678-9946 https://doaj.org/article/cef310a21ddf41d89a8d599e52e26551 |
op_doi |
https://doi.org/10.1590/S0036-46651993000300011 |
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Revista do Instituto de Medicina Tropical de São Paulo |
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35 |
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3 |
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285 |
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290 |
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