Blastocystis colonization and associations with population parameters in Thai adults.
Background Blastocystis is a unicellular eukaryote commonly found in the intestinal tract of humans and other animals. The prevalence of Blastocystis has been investigated in both developed and developing countries, yet its occurrence and distribution in rural locations has been less studied. Herein...
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ftdoajarticles:oai:doaj.org/article:ced0d512b0eb4fa9881a52cf31d0377c 2024-09-09T19:27:07+00:00 Blastocystis colonization and associations with population parameters in Thai adults. Vasana Jinatham Amara Yowang Christen Rune Stensvold Eleni Michalopoulou Thanakrit Vichasilp Picha Suwannahitatorn Siam Popluechai Anastasios D Tsaousis Eleni Gentekaki 2024-07-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0012292 https://doaj.org/article/ced0d512b0eb4fa9881a52cf31d0377c EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0012292 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0012292 https://doaj.org/article/ced0d512b0eb4fa9881a52cf31d0377c PLoS Neglected Tropical Diseases, Vol 18, Iss 7, p e0012292 (2024) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2024 ftdoajarticles https://doi.org/10.1371/journal.pntd.0012292 2024-08-19T14:56:42Z Background Blastocystis is a unicellular eukaryote commonly found in the intestinal tract of humans and other animals. The prevalence of Blastocystis has been investigated in both developed and developing countries, yet its occurrence and distribution in rural locations has been less studied. Herein, we aimed to examine the distribution of Blastocystis colonization in Thai adults representing background populations along a rural/peri-urban gradient, as well as associations between colonization and personal characteristics. Methodology A total of 238 participants were recruited from rural and peri-urban areas situated in three provinces. The presence of Blastocystis in feces was evaluated using PCR and qPCR. Information on gender, age, region (province), rural/peri-urban location, and body mass index (BMI) was collected. Principal findings The overall rate of Blastocystis carriage was 67.2%. Univariate analysis revealed significant associations between Blastocystis carriage and region (p<0.05), location (p<0.001) and age group (p<0.05). Logistic regression analysis revealed that rural/peri-urban location and BMI were significantly associated with Blastocystis carriage. Nine subtypes (ST1-ST7, ST10 and ST23) were identified with ST3, ST7 and ST1 as the most abundant ones, in this order. The greatest diversity of subtypes, in terms of numbers, was found in the middle aged group (nine subtypes), while the least diversity was found in the young adult and obese (three subtypes each) groups. Conclusions This study increases the understanding of the epidemiology of Blastocystis colonization and its association with population parameters and characteristics in middle-income countries. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 18 7 e0012292 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Vasana Jinatham Amara Yowang Christen Rune Stensvold Eleni Michalopoulou Thanakrit Vichasilp Picha Suwannahitatorn Siam Popluechai Anastasios D Tsaousis Eleni Gentekaki Blastocystis colonization and associations with population parameters in Thai adults. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Blastocystis is a unicellular eukaryote commonly found in the intestinal tract of humans and other animals. The prevalence of Blastocystis has been investigated in both developed and developing countries, yet its occurrence and distribution in rural locations has been less studied. Herein, we aimed to examine the distribution of Blastocystis colonization in Thai adults representing background populations along a rural/peri-urban gradient, as well as associations between colonization and personal characteristics. Methodology A total of 238 participants were recruited from rural and peri-urban areas situated in three provinces. The presence of Blastocystis in feces was evaluated using PCR and qPCR. Information on gender, age, region (province), rural/peri-urban location, and body mass index (BMI) was collected. Principal findings The overall rate of Blastocystis carriage was 67.2%. Univariate analysis revealed significant associations between Blastocystis carriage and region (p<0.05), location (p<0.001) and age group (p<0.05). Logistic regression analysis revealed that rural/peri-urban location and BMI were significantly associated with Blastocystis carriage. Nine subtypes (ST1-ST7, ST10 and ST23) were identified with ST3, ST7 and ST1 as the most abundant ones, in this order. The greatest diversity of subtypes, in terms of numbers, was found in the middle aged group (nine subtypes), while the least diversity was found in the young adult and obese (three subtypes each) groups. Conclusions This study increases the understanding of the epidemiology of Blastocystis colonization and its association with population parameters and characteristics in middle-income countries. |
format |
Article in Journal/Newspaper |
author |
Vasana Jinatham Amara Yowang Christen Rune Stensvold Eleni Michalopoulou Thanakrit Vichasilp Picha Suwannahitatorn Siam Popluechai Anastasios D Tsaousis Eleni Gentekaki |
author_facet |
Vasana Jinatham Amara Yowang Christen Rune Stensvold Eleni Michalopoulou Thanakrit Vichasilp Picha Suwannahitatorn Siam Popluechai Anastasios D Tsaousis Eleni Gentekaki |
author_sort |
Vasana Jinatham |
title |
Blastocystis colonization and associations with population parameters in Thai adults. |
title_short |
Blastocystis colonization and associations with population parameters in Thai adults. |
title_full |
Blastocystis colonization and associations with population parameters in Thai adults. |
title_fullStr |
Blastocystis colonization and associations with population parameters in Thai adults. |
title_full_unstemmed |
Blastocystis colonization and associations with population parameters in Thai adults. |
title_sort |
blastocystis colonization and associations with population parameters in thai adults. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2024 |
url |
https://doi.org/10.1371/journal.pntd.0012292 https://doaj.org/article/ced0d512b0eb4fa9881a52cf31d0377c |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 18, Iss 7, p e0012292 (2024) |
op_relation |
https://doi.org/10.1371/journal.pntd.0012292 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0012292 https://doaj.org/article/ced0d512b0eb4fa9881a52cf31d0377c |
op_doi |
https://doi.org/10.1371/journal.pntd.0012292 |
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PLOS Neglected Tropical Diseases |
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18 |
container_issue |
7 |
container_start_page |
e0012292 |
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1809896613332647936 |