Características clínico-evolutivas de 134 pacientes com histoplasmose disseminada associada a SIDA no Estado do Ceará Clinical and evolutionary characteristics of 134 patients with disseminated histoplasmosis associated with AIDS in the State of Ceará

INTRODUÇÃO: Desde o início da epidemia de HIV no Ceará, histoplasmose disseminada tem sido detectada com frequência em pacientes com aids. MÉTODOS: De modo a conhecer características clínico-laboratoriais, evolução e sobrevida da co-infecção HD/AIDS, analisou-se retrospectivamente 134 prontuários ca...

Full description

Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Lícia Borges Pontes, Terezinha do Menino Jesus Silva Leitão, Gabrielle Gurgel Lima, Emília Santiago Gerhard, Thyago Araújo Fernandes
Format: Article in Journal/Newspaper
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2010
Subjects:
Online Access:https://doi.org/10.1590/S0037-86822010000100007
https://doaj.org/article/cec273eb76ef45ffa3c462418ace71ab
id ftdoajarticles:oai:doaj.org/article:cec273eb76ef45ffa3c462418ace71ab
record_format openpolar
spelling ftdoajarticles:oai:doaj.org/article:cec273eb76ef45ffa3c462418ace71ab 2023-05-15T15:15:37+02:00 Características clínico-evolutivas de 134 pacientes com histoplasmose disseminada associada a SIDA no Estado do Ceará Clinical and evolutionary characteristics of 134 patients with disseminated histoplasmosis associated with AIDS in the State of Ceará Lícia Borges Pontes Terezinha do Menino Jesus Silva Leitão Gabrielle Gurgel Lima Emília Santiago Gerhard Thyago Araújo Fernandes 2010-02-01T00:00:00Z https://doi.org/10.1590/S0037-86822010000100007 https://doaj.org/article/cec273eb76ef45ffa3c462418ace71ab EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822010000100007 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 doi:10.1590/S0037-86822010000100007 0037-8682 1678-9849 https://doaj.org/article/cec273eb76ef45ffa3c462418ace71ab Revista da Sociedade Brasileira de Medicina Tropical, Vol 43, Iss 1, Pp 27-31 (2010) Histoplasmose disseminada AIDS Ceará Doença oportunista Disseminated histoplasmosis Opportunistic disease Arctic medicine. Tropical medicine RC955-962 article 2010 ftdoajarticles https://doi.org/10.1590/S0037-86822010000100007 2022-12-31T03:21:46Z INTRODUÇÃO: Desde o início da epidemia de HIV no Ceará, histoplasmose disseminada tem sido detectada com frequência em pacientes com aids. MÉTODOS: De modo a conhecer características clínico-laboratoriais, evolução e sobrevida da co-infecção HD/AIDS, analisou-se retrospectivamente 134 prontuários casos de HD internados de 1999 a 2005 no hospital referência para HIV no Ceará. RESULTADOS: Pacientes com HD apresentaram maior frequência de febre diária, tosse, perda de peso, hepatoesplenomegalia e insuficiência renal aguda. Diagnóstico foi dado por pesquisa e/ou cultura. À admissão, foram fatores de risco relacionados ao óbito de pacientes com HD: vômitos, dispnéia, insuficiência respiratória e IRA, hemoglobina<8g/L, uréia>40mg/dL e creatinina >1,5mg/dL. CONCLUSÕES: pacientes com HD apresentaram caracteristicamente febre mais elevada, internamentos anteriores por infecção respiratória, mais complicações clínicas e como fatores independentes para óbito, anemia importante e elevação de uréia. INTRODUCTION: Since the beginning of the HIV epidemic in Ceará, disseminated histoplasmosis (DH) has often been detected among AIDS patients. METHODS: In order to investigate the clinical and laboratory characteristics, evolution and survival of cases of DH/AIDS coinfection, the medical records on 134 cases of DH admitted to a reference hospital in Ceará between 1999 and 2005 were analyzed. RESULTS: Patients with DH presented higher frequency of daily fever, coughing, weight loss, enlarged liver and spleen and acute kidney failure. The diagnosis was made using investigation and/or cultures. At admission, the following were risk factors for death among DH patients: vomiting, dyspnea, respiratory failure, acute kidney failure, hemoglobin < 8g/l, urea > 40mg/dl and creatinine >1.5 mg/dl. CONCLUSIONS: Patients with DH characteristically presented higher fever, previous hospitalization due to respiratory infection and more clinical complications. Significant anemia and elevated urea were independent risk factors for ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Aguda ENVELOPE(-26.750,-26.750,-76.150,-76.150) Sida ENVELOPE(101.683,101.683,67.800,67.800) Revista da Sociedade Brasileira de Medicina Tropical 43 1 27 31
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
topic Histoplasmose disseminada
AIDS
Ceará
Doença oportunista
Disseminated histoplasmosis
Opportunistic disease
Arctic medicine. Tropical medicine
RC955-962
spellingShingle Histoplasmose disseminada
AIDS
Ceará
Doença oportunista
Disseminated histoplasmosis
Opportunistic disease
Arctic medicine. Tropical medicine
RC955-962
Lícia Borges Pontes
Terezinha do Menino Jesus Silva Leitão
Gabrielle Gurgel Lima
Emília Santiago Gerhard
Thyago Araújo Fernandes
Características clínico-evolutivas de 134 pacientes com histoplasmose disseminada associada a SIDA no Estado do Ceará Clinical and evolutionary characteristics of 134 patients with disseminated histoplasmosis associated with AIDS in the State of Ceará
topic_facet Histoplasmose disseminada
AIDS
Ceará
Doença oportunista
Disseminated histoplasmosis
Opportunistic disease
Arctic medicine. Tropical medicine
RC955-962
description INTRODUÇÃO: Desde o início da epidemia de HIV no Ceará, histoplasmose disseminada tem sido detectada com frequência em pacientes com aids. MÉTODOS: De modo a conhecer características clínico-laboratoriais, evolução e sobrevida da co-infecção HD/AIDS, analisou-se retrospectivamente 134 prontuários casos de HD internados de 1999 a 2005 no hospital referência para HIV no Ceará. RESULTADOS: Pacientes com HD apresentaram maior frequência de febre diária, tosse, perda de peso, hepatoesplenomegalia e insuficiência renal aguda. Diagnóstico foi dado por pesquisa e/ou cultura. À admissão, foram fatores de risco relacionados ao óbito de pacientes com HD: vômitos, dispnéia, insuficiência respiratória e IRA, hemoglobina<8g/L, uréia>40mg/dL e creatinina >1,5mg/dL. CONCLUSÕES: pacientes com HD apresentaram caracteristicamente febre mais elevada, internamentos anteriores por infecção respiratória, mais complicações clínicas e como fatores independentes para óbito, anemia importante e elevação de uréia. INTRODUCTION: Since the beginning of the HIV epidemic in Ceará, disseminated histoplasmosis (DH) has often been detected among AIDS patients. METHODS: In order to investigate the clinical and laboratory characteristics, evolution and survival of cases of DH/AIDS coinfection, the medical records on 134 cases of DH admitted to a reference hospital in Ceará between 1999 and 2005 were analyzed. RESULTS: Patients with DH presented higher frequency of daily fever, coughing, weight loss, enlarged liver and spleen and acute kidney failure. The diagnosis was made using investigation and/or cultures. At admission, the following were risk factors for death among DH patients: vomiting, dyspnea, respiratory failure, acute kidney failure, hemoglobin < 8g/l, urea > 40mg/dl and creatinine >1.5 mg/dl. CONCLUSIONS: Patients with DH characteristically presented higher fever, previous hospitalization due to respiratory infection and more clinical complications. Significant anemia and elevated urea were independent risk factors for ...
format Article in Journal/Newspaper
author Lícia Borges Pontes
Terezinha do Menino Jesus Silva Leitão
Gabrielle Gurgel Lima
Emília Santiago Gerhard
Thyago Araújo Fernandes
author_facet Lícia Borges Pontes
Terezinha do Menino Jesus Silva Leitão
Gabrielle Gurgel Lima
Emília Santiago Gerhard
Thyago Araújo Fernandes
author_sort Lícia Borges Pontes
title Características clínico-evolutivas de 134 pacientes com histoplasmose disseminada associada a SIDA no Estado do Ceará Clinical and evolutionary characteristics of 134 patients with disseminated histoplasmosis associated with AIDS in the State of Ceará
title_short Características clínico-evolutivas de 134 pacientes com histoplasmose disseminada associada a SIDA no Estado do Ceará Clinical and evolutionary characteristics of 134 patients with disseminated histoplasmosis associated with AIDS in the State of Ceará
title_full Características clínico-evolutivas de 134 pacientes com histoplasmose disseminada associada a SIDA no Estado do Ceará Clinical and evolutionary characteristics of 134 patients with disseminated histoplasmosis associated with AIDS in the State of Ceará
title_fullStr Características clínico-evolutivas de 134 pacientes com histoplasmose disseminada associada a SIDA no Estado do Ceará Clinical and evolutionary characteristics of 134 patients with disseminated histoplasmosis associated with AIDS in the State of Ceará
title_full_unstemmed Características clínico-evolutivas de 134 pacientes com histoplasmose disseminada associada a SIDA no Estado do Ceará Clinical and evolutionary characteristics of 134 patients with disseminated histoplasmosis associated with AIDS in the State of Ceará
title_sort características clínico-evolutivas de 134 pacientes com histoplasmose disseminada associada a sida no estado do ceará clinical and evolutionary characteristics of 134 patients with disseminated histoplasmosis associated with aids in the state of ceará
publisher Sociedade Brasileira de Medicina Tropical (SBMT)
publishDate 2010
url https://doi.org/10.1590/S0037-86822010000100007
https://doaj.org/article/cec273eb76ef45ffa3c462418ace71ab
long_lat ENVELOPE(-26.750,-26.750,-76.150,-76.150)
ENVELOPE(101.683,101.683,67.800,67.800)
geographic Arctic
Aguda
Sida
geographic_facet Arctic
Aguda
Sida
genre Arctic
genre_facet Arctic
op_source Revista da Sociedade Brasileira de Medicina Tropical, Vol 43, Iss 1, Pp 27-31 (2010)
op_relation http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822010000100007
https://doaj.org/toc/0037-8682
https://doaj.org/toc/1678-9849
doi:10.1590/S0037-86822010000100007
0037-8682
1678-9849
https://doaj.org/article/cec273eb76ef45ffa3c462418ace71ab
op_doi https://doi.org/10.1590/S0037-86822010000100007
container_title Revista da Sociedade Brasileira de Medicina Tropical
container_volume 43
container_issue 1
container_start_page 27
op_container_end_page 31
_version_ 1766345978226409472