Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus in Mexico.
BACKGROUND:ZIKV is a new addition to the arboviruses circulating in the New World, with more than 1 million cases since its introduction in 2015. A growing number of studies have reported vector competence (VC) of Aedes mosquitoes from several areas of the world for ZIKV transmission. Some studies h...
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2018
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Online Access: | https://doi.org/10.1371/journal.pntd.0006599 https://doaj.org/article/cebe4fdce7fc42d8bbc9d2e423a469ad |
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ftdoajarticles:oai:doaj.org/article:cebe4fdce7fc42d8bbc9d2e423a469ad 2023-05-15T15:12:03+02:00 Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus in Mexico. Selene M Garcia-Luna James Weger-Lucarelli Claudia Rückert Reyes A Murrieta Michael C Young Alex D Byas Joseph R Fauver Rushika Perera Adriana E Flores-Suarez Gustavo Ponce-Garcia Americo D Rodriguez Gregory D Ebel William C Black 2018-07-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0006599 https://doaj.org/article/cebe4fdce7fc42d8bbc9d2e423a469ad EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC6044546?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006599 https://doaj.org/article/cebe4fdce7fc42d8bbc9d2e423a469ad PLoS Neglected Tropical Diseases, Vol 12, Iss 7, p e0006599 (2018) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2018 ftdoajarticles https://doi.org/10.1371/journal.pntd.0006599 2022-12-31T00:23:26Z BACKGROUND:ZIKV is a new addition to the arboviruses circulating in the New World, with more than 1 million cases since its introduction in 2015. A growing number of studies have reported vector competence (VC) of Aedes mosquitoes from several areas of the world for ZIKV transmission. Some studies have used New World mosquitoes from disparate regions and concluded that these have a variable but relatively low competence for the Asian lineage of ZIKV. METHODOLOGY/PRINCIPAL FINDINGS:Ten Aedes aegypti (L) and three Ae. albopictus (Skuse) collections made in 2016 from throughout Mexico were analyzed for ZIKV (PRVABC59-Asian lineage) VC. Mexican Ae. aegypti had high rates of midgut infection (MIR), dissemination (DIR) and salivary gland infection (SGIR) but low to moderate transmission rates (TR). It is unclear whether this low TR was due to heritable salivary gland escape barriers or to underestimating the amount of virus in saliva due to the loss of virus during filtering and random losses on surfaces when working with small volumes. VC varied among collections, geographic regions and whether the collection was made north or south of the Neovolcanic axis (NVA). The four rates were consistently lower in northeastern Mexico, highest in collections along the Pacific coast and intermediate in the Yucatan. All rates were lowest north of the NVA. It was difficult to assess VC in Ae. albopictus because rates varied depending upon the number of generations in the laboratory. CONCLUSIONS/SIGNIFICANCE:Mexican Ae. aegypti and Ae. albopictus are competent vectors of ZIKV. There is however large variance in vector competence among geographic sites and regions. At 14 days post infection, TR varied from 8-51% in Ae. aegypti and from 2-26% in Ae. albopictus. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Pacific PLOS Neglected Tropical Diseases 12 7 e0006599 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Selene M Garcia-Luna James Weger-Lucarelli Claudia Rückert Reyes A Murrieta Michael C Young Alex D Byas Joseph R Fauver Rushika Perera Adriana E Flores-Suarez Gustavo Ponce-Garcia Americo D Rodriguez Gregory D Ebel William C Black Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus in Mexico. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:ZIKV is a new addition to the arboviruses circulating in the New World, with more than 1 million cases since its introduction in 2015. A growing number of studies have reported vector competence (VC) of Aedes mosquitoes from several areas of the world for ZIKV transmission. Some studies have used New World mosquitoes from disparate regions and concluded that these have a variable but relatively low competence for the Asian lineage of ZIKV. METHODOLOGY/PRINCIPAL FINDINGS:Ten Aedes aegypti (L) and three Ae. albopictus (Skuse) collections made in 2016 from throughout Mexico were analyzed for ZIKV (PRVABC59-Asian lineage) VC. Mexican Ae. aegypti had high rates of midgut infection (MIR), dissemination (DIR) and salivary gland infection (SGIR) but low to moderate transmission rates (TR). It is unclear whether this low TR was due to heritable salivary gland escape barriers or to underestimating the amount of virus in saliva due to the loss of virus during filtering and random losses on surfaces when working with small volumes. VC varied among collections, geographic regions and whether the collection was made north or south of the Neovolcanic axis (NVA). The four rates were consistently lower in northeastern Mexico, highest in collections along the Pacific coast and intermediate in the Yucatan. All rates were lowest north of the NVA. It was difficult to assess VC in Ae. albopictus because rates varied depending upon the number of generations in the laboratory. CONCLUSIONS/SIGNIFICANCE:Mexican Ae. aegypti and Ae. albopictus are competent vectors of ZIKV. There is however large variance in vector competence among geographic sites and regions. At 14 days post infection, TR varied from 8-51% in Ae. aegypti and from 2-26% in Ae. albopictus. |
format |
Article in Journal/Newspaper |
author |
Selene M Garcia-Luna James Weger-Lucarelli Claudia Rückert Reyes A Murrieta Michael C Young Alex D Byas Joseph R Fauver Rushika Perera Adriana E Flores-Suarez Gustavo Ponce-Garcia Americo D Rodriguez Gregory D Ebel William C Black |
author_facet |
Selene M Garcia-Luna James Weger-Lucarelli Claudia Rückert Reyes A Murrieta Michael C Young Alex D Byas Joseph R Fauver Rushika Perera Adriana E Flores-Suarez Gustavo Ponce-Garcia Americo D Rodriguez Gregory D Ebel William C Black |
author_sort |
Selene M Garcia-Luna |
title |
Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus in Mexico. |
title_short |
Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus in Mexico. |
title_full |
Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus in Mexico. |
title_fullStr |
Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus in Mexico. |
title_full_unstemmed |
Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus in Mexico. |
title_sort |
variation in competence for zikv transmission by aedes aegypti and aedes albopictus in mexico. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2018 |
url |
https://doi.org/10.1371/journal.pntd.0006599 https://doaj.org/article/cebe4fdce7fc42d8bbc9d2e423a469ad |
geographic |
Arctic Pacific |
geographic_facet |
Arctic Pacific |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 12, Iss 7, p e0006599 (2018) |
op_relation |
http://europepmc.org/articles/PMC6044546?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006599 https://doaj.org/article/cebe4fdce7fc42d8bbc9d2e423a469ad |
op_doi |
https://doi.org/10.1371/journal.pntd.0006599 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
12 |
container_issue |
7 |
container_start_page |
e0006599 |
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1766342790945439744 |