Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Sebastiana Silva Sabino, Caio Augusto de Lima, Luiz Gustavo Machado, Paola Amaral de Campos, Astrídia Marília de Souza Fontes, Paulo Pinto Gontijo-Filho, Rosineide Marques Ribas
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2020
• Subjects: Intensive care unit; Infections associated with health care; Multidrug-resistant organism; Bloodstream infections; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/0037-8682-0106-2019; https://doaj.org/article/ce8e6b5eb69a463f9f62d71d9c612b0a

Abstract INTRODUCTION: The present study aimed to determine the incidence of health care-associated infections (HCAIs) and identify the main resistant microorganisms in intensive care unit (ICU) patients in a Brazilian university hospital. METHODS: A retrospective cohort study was conducted in a Brazilian teaching hospital between 2012 and 2014. RESULTS: Overall, 81.2% of the infections were acquired in the ICU. The most common resistant pathogenic phenotypes in all-site and bloodstream infections were oxacillin-resistant coagulase-negative staphylococci and carbapenem-resistant Acinetobacter spp. (89.9% and 87.4%; 80.6% and 70.0%), respectively. CONCLUSIONS: There is an urgent need to focus on HCAIs in ICUs in Brazil.