Candidíase em pacientes aidéticos
Trinta e cinco aidéticos entre 19 e 55 anos admitidos e tratados de candidíase no Hospital Emílio Ribas, SP, com ELISA positivo para HIV e confirmado pelo Western Blot. Tuberculose em 9 sendo 2 com pericardite; neurotoxoplasmose em 6; neurocriptococose em 5; herpes labial em 4; pneumocistose em 3 e...
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Sociedade Brasileira de Medicina Tropical (SBMT)
1992
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ftdoajarticles:oai:doaj.org/article:cde387b997ba490493c9776d583cd883 2023-05-15T15:17:30+02:00 Candidíase em pacientes aidéticos C.E.O.P. Campos R.P. Igreja E.P. Campos 1992-09-01T00:00:00Z https://doaj.org/article/cde387b997ba490493c9776d583cd883 EN ES PT eng spa por Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821992000300003 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/cde387b997ba490493c9776d583cd883 Revista da Sociedade Brasileira de Medicina Tropical, Vol 25, Iss 3, Pp 165-169 (1992) Candidíase AIDS Terapia: polienos e imidazóis Candidiasis Therapy: polyenes and imidazoles Arctic medicine. Tropical medicine RC955-962 article 1992 ftdoajarticles 2023-01-08T01:33:16Z Trinta e cinco aidéticos entre 19 e 55 anos admitidos e tratados de candidíase no Hospital Emílio Ribas, SP, com ELISA positivo para HIV e confirmado pelo Western Blot. Tuberculose em 9 sendo 2 com pericardite; neurotoxoplasmose em 6; neurocriptococose em 5; herpes labial em 4; pneumocistose em 3 e sarcoma de Kaposi em 2, achavam-se associadas. A concentração inibitória mínima 50% (MIC 50%) para os azoles foi: ketoconazol= 2,2 µg/ml; itraconazol- 21,0 µg/ml; fluconazol = 19,0 µg/ml. O MIC 50% para ospolienos: nistatina- 50,0 µg/ml; anfotericina B= 0,12 µg/ml e para 5 fluorcitosina= 1,6 µg/ml nas 35 amostras de Candida isoladas. Testes não paramétricos de Siegel revelaram significante identificação (80%) das Candida albicans na candidíase, e que a dose de AMB não modificou o número de óbitos, precoce e tardio, ocorridos nesses aidéticos. O uso prévio dos azoles e da nistatina explicaria, talvez, o elevado MIC 50% observado nas amostras de Candida isoladas. A total of 35 in patients admitted at Emilio Ribas Hospital - São Paulo, Brazil, with digestive candidiasis and AIDS clinical diagnostic were evaluated 10 month later, being 29 male and 6 female; white outnumbering black with age ranged from 30 to 50 years old. Agar Sabouraud culture and tube germinative tests identified 28 (80%) Candida albicans out 35 strains. Minimum inhibitory concentration (MIC) 50% was against azoles (ketoconazole= 2.2 µg/ml; itraconazole = 21.0 µg/ml and fluconazole- 19.0 µg/ml); polyenes (ny statine - 50.0 µg/ml and amphotericin B= 0.12 µg/ml) and 5 fluorcytosine= 1.6µg/ml. Siegeltests showed significant Candida albicans proportions in strains isolated from 35 AIDS patients. There was no significant relation between AMB dosis and early or late death. Conclusions: candidiasis in AIDS patients showed high MIC 50% to azoles and nystatine and significant Candida albicans proportion in all strains isolated from AIDS patients. Previous amphotericin B therapy had no influence in early or late death in 30 patients. Previous therapy possibily ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Elevado ENVELOPE(-63.267,-63.267,-64.683,-64.683) |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish Portuguese |
topic |
Candidíase AIDS Terapia: polienos e imidazóis Candidiasis Therapy: polyenes and imidazoles Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Candidíase AIDS Terapia: polienos e imidazóis Candidiasis Therapy: polyenes and imidazoles Arctic medicine. Tropical medicine RC955-962 C.E.O.P. Campos R.P. Igreja E.P. Campos Candidíase em pacientes aidéticos |
topic_facet |
Candidíase AIDS Terapia: polienos e imidazóis Candidiasis Therapy: polyenes and imidazoles Arctic medicine. Tropical medicine RC955-962 |
description |
Trinta e cinco aidéticos entre 19 e 55 anos admitidos e tratados de candidíase no Hospital Emílio Ribas, SP, com ELISA positivo para HIV e confirmado pelo Western Blot. Tuberculose em 9 sendo 2 com pericardite; neurotoxoplasmose em 6; neurocriptococose em 5; herpes labial em 4; pneumocistose em 3 e sarcoma de Kaposi em 2, achavam-se associadas. A concentração inibitória mínima 50% (MIC 50%) para os azoles foi: ketoconazol= 2,2 µg/ml; itraconazol- 21,0 µg/ml; fluconazol = 19,0 µg/ml. O MIC 50% para ospolienos: nistatina- 50,0 µg/ml; anfotericina B= 0,12 µg/ml e para 5 fluorcitosina= 1,6 µg/ml nas 35 amostras de Candida isoladas. Testes não paramétricos de Siegel revelaram significante identificação (80%) das Candida albicans na candidíase, e que a dose de AMB não modificou o número de óbitos, precoce e tardio, ocorridos nesses aidéticos. O uso prévio dos azoles e da nistatina explicaria, talvez, o elevado MIC 50% observado nas amostras de Candida isoladas. A total of 35 in patients admitted at Emilio Ribas Hospital - São Paulo, Brazil, with digestive candidiasis and AIDS clinical diagnostic were evaluated 10 month later, being 29 male and 6 female; white outnumbering black with age ranged from 30 to 50 years old. Agar Sabouraud culture and tube germinative tests identified 28 (80%) Candida albicans out 35 strains. Minimum inhibitory concentration (MIC) 50% was against azoles (ketoconazole= 2.2 µg/ml; itraconazole = 21.0 µg/ml and fluconazole- 19.0 µg/ml); polyenes (ny statine - 50.0 µg/ml and amphotericin B= 0.12 µg/ml) and 5 fluorcytosine= 1.6µg/ml. Siegeltests showed significant Candida albicans proportions in strains isolated from 35 AIDS patients. There was no significant relation between AMB dosis and early or late death. Conclusions: candidiasis in AIDS patients showed high MIC 50% to azoles and nystatine and significant Candida albicans proportion in all strains isolated from AIDS patients. Previous amphotericin B therapy had no influence in early or late death in 30 patients. Previous therapy possibily ... |
format |
Article in Journal/Newspaper |
author |
C.E.O.P. Campos R.P. Igreja E.P. Campos |
author_facet |
C.E.O.P. Campos R.P. Igreja E.P. Campos |
author_sort |
C.E.O.P. Campos |
title |
Candidíase em pacientes aidéticos |
title_short |
Candidíase em pacientes aidéticos |
title_full |
Candidíase em pacientes aidéticos |
title_fullStr |
Candidíase em pacientes aidéticos |
title_full_unstemmed |
Candidíase em pacientes aidéticos |
title_sort |
candidíase em pacientes aidéticos |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
1992 |
url |
https://doaj.org/article/cde387b997ba490493c9776d583cd883 |
long_lat |
ENVELOPE(-63.267,-63.267,-64.683,-64.683) |
geographic |
Arctic Elevado |
geographic_facet |
Arctic Elevado |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 25, Iss 3, Pp 165-169 (1992) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821992000300003 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/cde387b997ba490493c9776d583cd883 |
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1766347735246569472 |